Cell Culture Reagent, White Powder CAS Number: 69-52-3 Molecular Formula: C₁₆H₁₈N₃O₄SNa Molecular Weight: 371.4 Ampicillin sodium salt is a semi-synthetic derivative of penicillin, active as a broad-spectrum antibiotic. It is inactivated by…

Kanamycin is an aminoglycoside antibiotic effective against mycoplasma, gram-positive and gram-negative bacteria. It is used in biotechnology applications to inhibit protein synthesis. Mode of Action: Binds to 70S ribosomal subunit; inhibits translocation; elicits miscoding. Antimicrobial…

Mitomycin C is the most widely used of the Mitomycin antibiotics because it is the least toxic and with the most potent antitumor activity. Inhibitor of DNA synthesis, nuclear division, and cancer cells. Antibacterial to gram positive, gram negative, acid-fast bacilli. Mitomycin C…

Gentamicin Sulfate Solution is effective against gram-positive and gram-negative bacteria, as well as mycoplasma.

Ampicillin is a semi-synthetic derivative of penicillin, active as a broad-spectrum antibiotic. It is inactivated by beta-lactamases and for this reason a beta-lactamase inhibitor should be considered when using ampicillin. Against gram-positive bacteria, ampicillin has a similar mode of action as…

Kanamycin sulfate is an antimicrobial agent effective against Gram-negative and Gram-positive bacteria and mycoplasma. It binds to the 70S ribosomal subunit, inhibits translocation, and elicits miscoding. Cross-resistance occurs between kanamycin and neomycin, framycetin, and paromomycin, and…

Puromycin is an antibiotic of unique structure and biological activity. It is produced by fermentation using Streptomyces albo-niger. There are four aspects of puromycin's biological activity that are 1) antitumor effect; 2) nephrotoxic action; 3) inhibition of purine and/or protein synthesis…

This triple antibiotic solution contains penicillin (10,000 IU/mL), streptomycin (10 mg/mL), and amphotericin B (25 μg/mL). Applications Penicllin-Streptomycin-Amphotericin B is used to supplement cell culture media. It is effective against yeast, fungi, gram-positive and gram-negative…

Suitability: Suitable for cell culture Key Applications: Cell culture media supplement Product Type: Biochemicals Chemical Class: Antibiotics

Cytochalasin D is a cell permeable fungal toxin that binds to the barbed end of actin filaments inhibiting both the association and dissociation of subunits. This compound causes the disruption of actin filaments and inhibition of actin polymerization. Synonyms: Zygosporin A,…

Chlortetracycline hydrochloride has antimicrobial action similar to tetracycline hydrochloride, but it is somewhat less active against many Gram-negative organisms. It was first isolated from the culture of Streptomyces aureofacien. Cell-permeable fluorescent probe for Ca2+ for measuring calcium…

Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline. As a sulfonamide antibiotic, it functions by competitively inhibiting (i.e., by acting as a substrate analogue) enzymatic reactions involving para-aminobenzoic acid (PABA). PABA is needed in enzymatic…

G418 Sulfate is used as a selective antibiotic in the concentration range of 100 - 200 µg/mL for bacteria, or 200 – 500 µg/mL for most mammalian cells. It is also used for the selection of transfected mammalian cells, yeast, dictyostelium, plant and bacteria. G418 Sulfate is an…

Penicillin G also known as benzylpenicillin. It exert a bacteriocidal as well as a bacteriostatic effect on susceptible bacteria by interfering with the final stages of the synthesis of peptidoglycan, a substance in the bacterial cell wall. Penicillin G is a narrow spectrum antibiotic derived…

Indomethacin, an anti-inflammatory agent, inhibits Cox-1 and Cox-2 (cyclooxygenases) with selectivity for Cox-1 (IC50 of 230 nM) over Cox-2 (IC50 of 630 nM). Additionally, Indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor…

Bleomycin Sulfate is an atineoplastic antibiotic. A mixture of cytotonic glycopeptide antibiotics which reacts with DNA and causes strand scission; they have also been shown to have a type of oxygen transferase activity. Bleomycin A2 is the main component of the bleomycin employed clinically.…

Streptomycin Sulfate is an aminoglucoside antibiotic in which streptidine is linked glycosidically to the disaccharide streptobiosamine. Inhibit bacterial protein synthesis Gram positive bacteria Gram negative bacteria Mode of Action: Inhibits prokaryote protein synthesis. Binds to…

Tunicamycin is a mixture of Tunicamycins A, B, C and D. It is a nucleoside antibiotic active in vitro against Gram-positive bacteria, yeasts, fungi, and viruses. Tunicamycin has been used to study the effect of N-linked glycosylation of human proton-coupled folate transporter (HsPCFT) in HeLa…

Nalidixic acid sodium salt is an antibacterial agent (synthetic quinolone antibiotic), which is inhibitor of bacterial DNA polymerase (DNA gyrase) & avian myeloblastoma virus reverse transcriptase. Inhibits nucleic acid and protein synthesis in Saccharomyces cerevisiae. Typically used at a…

Applications Methyl(5-(2-thienylcarbonyl)-1H-benzimidazole-2-yl)carbamate is an anticancer drug that has been shown to interfere with the structure and function of microtubules in interphase and mitotic cells. Malignant cells may be more susceptible to the antimicrotubular effect of nocodazole…

Polymyxin B Sulfate is a mixture of Polymyxin B1 and Polymyxin B2 Sulfate, obtained from Bacillus polymyxia strains. Inhibits gram-negative organisms in vitro Binds to and interferes with permeability of bacterial cytoplasmic membrane Inhibits Ca2+ dependent protein kinase C (PKC) …

Cycloheximide is a glutarimide antibiotic derived from a microbial source. Cycloheximide is an antibiotic which is very active against many molds, yeasts, and phytopathogenic fungi. It exhibits somewhat lower activity against bacteria and certain fungi. Control of various molds and fungi in…

Amphotericin B is a polyene antifungal antibiotic from Streptomyces sp. It has a high affinity for sterols, primarily ergosterols, of fungal and bacterial cell membranes. It is an antibiotic solution effective against yeast and other fungi. Amphotericin B may be toxic to some insect cell types.…

Ampicillin is a semi-synthetic derivative of penicillin, active as a broad-spectrum antibiotic. It is inactivated by beta-lactamases and for this reason a beta-lactamase inhibitor should be considered when using ampicillin. Against gram-positive bacteria, ampicillin has a similar mode of action as…

Applications Mycoplasma Removal Agent (MRA) eliminates mycoplasma contamination from cell cultures. The cytotoxicity of MRA is low and cell toxicity is rare when used at the recommended concentration. For specific function of any cell, however, it is recommended that the retention of desired…

Amikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections. Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth. Amikacin must be given by the…

Gentamicin Sulfate Reagent Solution is recommended for use in cell culture applications at 5 ml/L and used as a selection agent (gentamicin-resistance gene) in molecular biology applications. Gentamicin is an aminoglycoside antibiotic complex produced by fermentation of Micromonospora purpurea…

Sorbic acid (2,4-hexadienoic acid) is a straight chain unsaturated fatty acid. It is an antimicrobial agent. The antimicrobial action of sorbic acid is due to its inhibitory influence on various enzymes in the microbial cell such as enzymes involved in carbohydrate metabolism such as enolase and…

Cefsulodin is a third generation cephalosporin antibiotic that has very specific activity against Pseudomonas aeruginosa. It has no significant activity against other Gram-negative bacteria and very limited activity against Gram-positive bacteria and anaerobic bacteria. Cefuslodin is most…

An antiseptic and disinfectant agent. It is effective against a wide range of bacteria, some fungi and some viruses, and an agent for the prevention of gingivitis. Commercial ophthalmic products have used this agent to replace thimerosal as a preservative; however, it can cause skin irritation. …

Penicillin G is a narrow spectrum antibiotic. Active against gram-positive and gram-negative aerobic and anaerobic bacteria Inhibits cell wall synthesis Stable against hydrolysis by β-lactamases, such as penicillinases and cephalosporinases The drug of choice for Streptococcus…

Spectinomycin sulfate is an antibiotic which binds to the 30S subunit to cause misreading. Spectinomycin sulfate is a broad spectrum antibiotic that inhibits protein synthesis (elongation) by binding to the bacterial 30S ribosomal subunit and interfering with peptidyl tRNA translocation.