Geneticin

Mode of Action: G-418 inhibits protein elongation by blocking polypeptide synthesis. Eukaryotic cells that are stably transfected with neomycin resistance genes can be selected and maintained using this product. Similar in structure to Gentamicin, Neomycin, and Kanamycin. Store dessicated at…

Synonyms: Antibiotic G418G 418 disulfate saltAminoglycoside antibiotic Purity Limit: Potency ≥ 700 ug/mg (anhydrous basis) CAS No.: 108321-42-2 Molecular Formula: C20H40N4O10·2H2SO4 Molecular Weight: 692.7 MDL No.: MFCD00058314 Appearance: White to off-white powder Comments: …

Synonym(s): Geneticin Formula: C20H40N4O10 2H2SO4 Formula weight: 692.71 CAS Number: 108321-42-2 Harmonized Tariff Code:  2941.90

Synonym(s): Geneticin disulfate Formula: C20H40N4O10 2H2SO4 Formula weight: 692.71 CAS Number: 108321-42-2 Harmonized Tariff Code:  2941.90

…isolated from Micromonospora rhodorangea and is closely related to the gentamicins; most notably, genatmicin B1. G418 is a generic name of Geneticin®. G418 blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. G418 is commonly used in…

G418 Sulfate is used as a selective antibiotic in the concentration range of 100 - 200 µg/mL for bacteria, or 200 – 500 µg/mL for most mammalian cells. It is also used for the selection of transfected mammalian cells, yeast, dictyostelium, plant and bacteria. G418 Sulfate is an…

…lines: L. Qian, et al.; Histochem. Cell Biol. 126, 593 (2006) Antiviral activity of geneticin against bovine viral diarrhoea virus: A.V. Birk, et al.; Antivir. Chem. Chemother. 19, 33 (2008) Antiviral activity of geneticin against dengue virus: X.G. Zhang, et al.; Antiviral Res. 83, 21 (2009)

…rat1. The INS-1 832/3 cell line is a subclone of INS-1 that was stably transfected with a CMV promoter-human insulin expression plasmid carrying a geneticin (G418)-resistance marker for selection . Synonyms: INS1 832/3, INS-1 (832/3), 832/3 Application: This product is intended for sale and…

Polypeptide synthesis inhibitor G418 blocks the elongation step in prokaryotic and eukaryotic cells. Selects eukaryotic cells stably transfected with neomycin-resistant genes Useful as a selective agent in gene transfer experiments Supplied as a crystalline solid or aqueous solution G418…