Enzymes & Inhibitors

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MP Biomedicals Enzymes & Inhibitors

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  • Lysozyme from Chicken Eggwhite

    MP Biomedicals

    Lysozyme (muramidase) hydrolyzes preferentially the β-1,4 glucosidic linkages between N-acetylmuramic acid and N-acetylglucosamine which occur in the mucopeptide cell wall structure of certain microorganisms, such as Micrococcus lysodeikticus. Extracts group specific antigens …

  • Deoxyribonuclease I from Bovine Pancreas

    MP Biomedicals

    Deoxyribonuclease from beef pancreas, DNase I, was first crystallized by Kunitz. It is an endonuclease which splits phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide yielding 5'-phosphate terminated polynucleotides with a free hydroxyl group on position 3'. The…

  • Aldehyde Dehydrogenase from Yeast

    MP Biomedicals

    Aldehyde dehydrogenase belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. Aldehyde dehydrogenase oxidizes a number of aliphatic and aromatic aldehydes. Acetyl-GSH is not hydrolyzed. Aldehyde dehydrogenase…

  • Glucose Oxidase from Aspergillus niger

    MP Biomedicals

    Glucose oxidase is an FAD-containing glycoprotein. The enzyme is specific for β-D-glucose. O can be replaced by hydrogen acceptors such as 2,6-dichlorophenol indophenol. Glucose oxidase from Aspergillus niger is a dimer consisting of 2 equal subunits with a molecular mass of 80 kDa each. Each…

  • Diastase from Malt

    MP Biomedicals

    1X N.F. Stable, 60 mesh powder. 1 gram will digest 50 gram starch in 30 minutes.

  • Yeast Lytic Enzyme from Arthrobacter luteus

    MP Biomedicals

    Yeast lytic enzyme is used to digest the cell wall of active yeast cells. Yeast lytic enzyme is an enzyme preparation from a submerged culture of Arthrobacter luteus which effectively lyses cell walls of viable yeast cell. It is a lyophilized enzyme partially purified by affinity chromatography.…

  • Lactase from Aspergillus oryzae

    MP Biomedicals

    Lactase is an enzyme preparation produced by Aspergillus oryzae fermentation. Hydrolyzes Lactose Produces β-D-Galactose and a-D-Glucose One unit will hydrolyze 1.0 µmole of o-nitrophenyl-beta-D-galactoside to o-nitrophenol per minute at pH 4.5 and 30°C …

  • Peroxidase from Horseradish (Amoracia rusticana)

    MP Biomedicals

    HRP is a plant glycohemoprotein that belongs to the ferroprotoporphyrin group of peroxidases. HRP is composed of seven isozymes. All isozymes contain photohemin IX as prosthetic group. Neutral and amino sugars account for approximately 18% of the enzyme. The iron-containing hemin group is…

  • Kifunensine

    MP Biomedicals

    Kifunensine is an alkaloid compound, originally isolated from the actinomycete Kitasporia kifunensis, that exhibits potent and selective inhibition of class I α-mannosidases. Kifunensine is used to suppress Endoplasmic Reticulum-Associated Degradation (ERAD) via the inhibition of endoplasmic…

  • Bilirubin Oxidase from Myrothecium species

    MP Biomedicals

    Bilirubin oxidase is used to degrade bilirubin. Bilirubin oxidase, from Myrothecium verrucaria, may be used to determine free hemoglobin in icteric specimens. It also has potential application in dye effluent decolorization and is a potential treatment for neonatal jaundice. It is used in…

  • BOC-ASP(OMe)-FMK

    MP Biomedicals

    The FMK peptides are potent, cell permeable, irreversible inhibitors. It is useful for in vitro and in vivo applications. BOC-ASP(OMe)-FMK is an inhibitor for general Caspases. The novel Boc-D(OMe)-FMK inhibitor synthesized using proprietary technology is cell permeable and irreversibly binds to…

  • Acetyl Coenzyme A Trilithium Salt Trihydrate

    MP Biomedicals

    Acetyl-CoA is produced via beta-oxidation of fatty acids, via the metabolism of carbohydrates - glucose 6-phosphate to pyruvate to acetyl-CoA and via the catabolism of amino acids. Acetyl-CoA has a number of metabolic opportunities. It is metabolized in the tricarboxylic acid cycle to produce…

  • Lysozyme from Chicken Eggwhite

    MP Biomedicals

    Lysozyme (muramidase) hydrolyzes preferentially the β-1,4 glucosidic linkages between N-acetylmuramic acid and N-acetylglucosamine which occur in the mucopeptide cell wall structure of certain microorganisms, such as Micrococcus lysodeikticus. Extracts group specific antigens …

  • Creatinine Deiminase from Microbial

    MP Biomedicals

    Creatinine deiminase has been used in a study to assess the application of a creatinine-sensitive biosensor for hemodialysis control. Creatinine deiminase has also been used in a study to investigate the bioelectronic tongue for the simultaneous determination of urea, creatinine and alkaline ions…

  • Probenecid

    MP Biomedicals

    Probenecid is a uricosuric agent, which increases uric acid removal in the urine. It also reduces the renal tubular excretion of many other drugs and increases their plasma concentration. Probenecid is useful as an inhibitor of the organic anion transporter. Probenecid is an inhibitor of…

  • Pancreatin 8X from Porcine Pancreas

    MP Biomedicals

    Pancreatin is a mixture of several digestive enzymes produced by the exocrine cells of the porcine pancreas and delivered to the small intestine for the hydrolysis of complex nutrients. It is a broad-spectrum protease composed of amylase, trypsin, lipase, ribonuclease and protease. Pancreatin…

  • Cholesterol Esterase

    MP Biomedicals

    Cholesterol Esterase is useful for enzymatic determination of total cholesterol when coupled with cholesterol oxidase in clinical analysis. Stored intracellularly as cholesterol esters Reversible enzyme Hydrolyzes and synthesizes fatty acid esters of cholesterol and other sterols …

  • Pepsin from Porcine

    MP Biomedicals

    Pepsin, an acid protease, contains a proteolytic enzyme. Pepsin contains the "cathepsin" component which has milk curdling activity. It has a broad range of substrate activity and demonstrates an esterase acitivity. It generally attacks peptide bonds. Pepsin is a peptidase used to…

  • Cathepsin G from Human Neutrophils

    MP Biomedicals

    Cathepsin G is a serine protease that degrades collagen and proteoglycans. It has been implicated in connective tissue-related disorders. Cathepsin G from human leukocytes is a glycoprotein containing approximately 1% carbohydrate. It is considered to be a major constituent of human neutophil…

  • Lipase from Porcine

    MP Biomedicals

    Lipases are a subclass of the esterases. It catalyzes the hydrolysis of emulsified esters of glycerol and long chain fatty acids. Lipases are used industrially for the resolution of chiral compounds and the transesterification production of biodiesel. Lipases catalyze the hydrolysis of esters…

  • Trypsin from Porcine

    MP Biomedicals

    The typical use for this product is in removing adherent cells from a culture surface. The concentration of trypsin necessary to dislodge cells from their substrate is dependent primarily on the cell type and the age of the culture. Trypsins have also been used for the re-suspension of cells during…

  • Collagenase Type 3 from Clostridium histolyticum

    MP Biomedicals

    Collagenases degrade native helical collagen fibrils. The substrate, collagen, is the major fibrous component of animal extracellular connective tissue: skin, tendon, blood vessels, bone, etc. True collagenase may cleave simultaneously across all three chains or attack a single strand. The enzyme…

  • Collagenase Type IV from Clostridium histolyticum

    MP Biomedicals

    Collagenases degrade native helical collagen fibrils. It has an important role in connective tissue metabolism and is produced by specific cells involved in repairs and remodelling processes. Collagenase is used for tissue dissociation combined with other enzymes such as elastase, trypsin,…

  • Hydroxylamine Hydrochloride

    MP Biomedicals

    MAO inhibitor; inhibits platelet aggregation.

  • Iodoacetamide

    MP Biomedicals

    Iodoacetamide is a thiol reagent; alkylating reagent for cysteine and histidine residues in proteins. In the alkylation reaction, it reacts with histidine (such as in RNase), methionine and sulfhydryl groups of many proteins. Iodoacetamide can react with low molecular weight thiol compounds such as…

  • Protease Inhibitor Cocktail Kit

    MP Biomedicals

    Protease Inhibitor Cocktail Kit is a broad spectrum protease inhibitor cocktail which covers both endopeptidases and exopeptidases, non-specific and specific. The cocktail consists of four major protease inhibitors: AEBSF, Sodium EDTA, Leupeptin and Pepstatin A. Protease Inhibitor Cocktail Kit…

  • p-Nitrophenyl Phopshate Disodium Salt Hexahydrate

    MP Biomedicals

    p-nitrophenol is suitable for use as a substrate for alkaline and acid phosphatase. p nitrophenol is the substrate of choice for use with alkaline phosphatase in ELISA procedures. This substrate produces a soluble end product that is yellow in color and can be read spectrophotometrically at 405…

  • a-Amylase from Porcine Pancreas

    MP Biomedicals

    α-Amylase isolated from porcine pancreas is a glycoprotein. It is a single polypeptide chain of ~475 residues containing two SH groups and four disulfide bridges and a tightly bound Ca2+ necessary for stability. Chloride ions are necessary for activity and stability. α-Amylase is…

  • ß-Glucuronidase from Helix pomatia

    MP Biomedicals

    Beta-glucuronidases are members of the glycosidase family of enzymes that catalyze breakdown of complex carbohydrates. Human β-glucuronidase is a type of glucuronidase that catalyzes hydrolysis of β-D-glucuronic acid residues from the non-reducing end of mucopolysaccharides such as…

  • Conduritol B Epoxide

    MP Biomedicals

    Conduritol B Epoxide (CBE) is a potent, irreversible inhibitor of various plant β-glucosidases and mammalian glucocerebrosidase, specific covalent inhibitor of β-glucosidase which results in the accumulation of glucocerebroside. In vitro exposure of cells to CBE has been reported to…

  • Hemin Chloride from Porcine

    MP Biomedicals

    Hemin is an iron-containing porphyrin. It is a Protoporphyrin IX containing a ferric iron ion (Heme B) with a chloride ligand. Hemin is used in the management of porphyria attacks, particularly in acute intermittent porphyria. It may be used to study the expression and repression of heme…

  • a-Amylase from Bacillus subtilis

    MP Biomedicals

    This α-amylase product is a liquefying diastase supplied as a dry, free-flowing powder having high uniformity and excellent storage stability. The general procedure for the enzymatic liquefaction of starch is the same, regardless of the nature of the end product. The degree of conversion…

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