Enzymes & Inhibitors

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G-Biosciences Enzymes & Inhibitors

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  • PhosphataseArrest™

    G-Biosciences

    The PhosphataseArrest™ phosphatase inhibitor cocktails are 100X concentrated, ready-to-use solutions that are simply added to your extraction buffers or samples. PhosphataseArrest™ is ideal for inhibition in tissue extractions and cell lysis experiments and is compatible with most…

  • LongLife™ Lysozyme

    G-Biosciences

    Enzymes regularly used in laboratory applications often require preparation of fresh solution before each use. Making fresh enzyme solution for each application is time consuming and wasteful. A wide variety of enzyme preparations in a ready-to-use format are offered. LongLife™ enzyme…

  • Doxorubicin [2mM]

    G-Biosciences

    ((8S,10S)-10-(4-amino-5-hydroxy-6-methyl-tetrahydro-2H-pyran-2-yloxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione) Doxorubicin (or hydroxyldaunorubicin) is an anthracycline antibiotic that intercalates DNA, inhibiting the unwinding of DNA by…

  • Antipain-dihydrochloride

    G-Biosciences

    [(S)-1-Carboxy-2-Phenyl]-carbamoyl-Arg-Val-arginal Specificity: Inhibits Ca 2+ -dependent endopeptidases, including papain, trypsin-like serine proteases, some cysteine proteases and to a lesser extent plasmin. Higher specificity for trypsin and papain compared to leupeptin. Solubility: …

  • Immobilized Papain

    G-Biosciences

    Papain is a cysteine protease enzyme (EC 3.4.22.2) that has the endopeptidase activity to cleave immunoglobulin G molecules in the hinge region. This cleavage results in the generation of three ~50kDa fragments; two Fab domains and a Fc domain. The papain-digested antibody is unable to promote…

  • Trypsin is a serine protease that cleaves peptides on C-terminal end of lysine and arginine amino acid residues. The pH optimum of trypsin is pH 7.0-8.0. Trypsin is inhibited by serine protease inhibitors including TLCK (N-p-tosyl-L-lysine chloromethyl ketone), PMSF (phenylmethanesulfonyl…

  • ProteaseArrest™

    G-Biosciences

    ProteaseArrest™ is a general protease inhibitor cocktail solution that is provided as a 100X concentrated, ready-to-use solution. The ProteaseArrest™ 100X solution format is suitable for small, analytical sample applications, as >95% inhibition is achieved by adding 10µl…

  • Staurosporine

    G-Biosciences

    Staurosporine is a strong inhibitor of phosphalipid/Ca2+ dependent protein kinase and platelet aggregation. It is most commonly used as an inducer of apoptosis in several mammalian cell types. It is also used to study role of protein kinases in signal transduction as it inhibits other protein…

  • A broad range, 100X concentrated, ready-to-use protease inhibitor cocktail. Plant ProteaseArrest™ inhibits plant serine, cysteine and other plant specific proteases including aminopeptidases, aspartic and metalloproteases. ProteaseArrest Family Our ProteaseArrest™ is a…

  • Bestatin

    G-Biosciences

    N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine hydrochloride Specificity: Competitive inhibitor of surface aminopeptidases, including aminopeptidase B (Ki=2nM), leucine aminopeptidase (Ki=20nM). Also inhibits aminopeptidases N; does not inhibit endoproteases. …

  • Adenine Deaminase (EC 3.5.4.2) converts Adenine to Hypoxanthine. A highly purified recombinant enzyme protein supplied at a 2µM concentration.

  • A Chemically Modified, TPCK treated, Affinity Purified Trypsin Trypsin is a serine endopeptidase that specifically cleaves peptide bonds on the carboxy side of s-aminoethyl cysteine, arginine and lysine residues, and typically, there is little to no cleavage at arginyl-proline and lysyl-proline…

  • Features Synonyms: α-Toluenesulfonyl fluoride, Benzylsulfonyl fluoride, Phenylmethylsulfonyl fluoride CAS Number: 329-98-6 Molecular Formula: C₇H₇FOâ‚‚S Molecular Weight: 174.19 g/mol Activity: >99.9% …

  • Aprotinin

    G-Biosciences

    Also known as bovine pancreatic trypsin inhibitor. Activity: Approx 6,000 KIU/mg Specificity: A broad range, competitive and reversible inhibitor of chymotrypsin, plasmin, trypsin, kallikrein and other serine proteases Solubility: Soluble in water (Stock solution: 10mM) A…

  • SG-Carboxypeptidase B (Recombinant)™is the rat carboxypeptidase B expressed in E. coli. Carboxypeptidase B specifically hydrolyses basic amino acids including lysine, arginine and histidine from the C-terminal end of polypeptides. It is used in sequencing protein and peptides. Other…

  • LongLife™ Zymolyase®

    G-Biosciences

    Enzymes regularly used in laboratory applications often require preparation of fresh solution before each use. Making fresh enzyme solution for each application is time consuming and wasteful. G-Biosciences offersa wide variety of fresh, ready-to-use enzyme preparations. Our high performance…

  • LongLife™ DNase

    G-Biosciences

    Enzymes regularly used in laboratory applications often require preparation of fresh solution before each use. Making fresh enzyme solution for each application is time consuming and wasteful. A wide variety of enzyme preparations in a ready-to-use format are offered. LongLife™ enzyme…

  • Pfu Polymerase

    G-Biosciences

    Pfu DNA polymerase, derived from the hyperthermophilic archae Pyrococcus furiosus, has superior thermostability and proofreading properties compared to other thermostable polymerase. Its molecular weight is 90 kD. It can amplify DNA target up to 2kb. The elongation velocity is 0.2~0.4kb/min…

  • SG-Glutamic-C™

    G-Biosciences

    SG -Glutamic-C ™ is a serine endopeptidase, from S. aureus V8 , that is highly specific for the cleavage of peptide bonds at the carboxy side of either aspartic or glutamic acid, depending on the buffer used. In Tris-HCl buffer, in particular in the absence of phosphate ions, the enzyme is…

  • Enzymes regularly used in laboratory applications often require preparation of fresh solution before each use. Making fresh enzyme solution for each application is time consuming and wasteful. A wide variety of enzyme preparations in a ready-to-use format are offered. LongLife™ enzyme…

  • Firefly luciferase is a unique photoprotein used in bioluminescence for high sensitive detection and quantification of ATP and as a reporter for studying gene function and regulation.Luciferase (Firefly, Recombinant) is recombinant 62 kDa protein expressed in E. Coli. Click here to request…

  • A broad range, 100X concentrated, ready-to-use protease inhibitor cocktail. Mammalian ProteaseArrest™ inhibits mammalian serine, cysteine and other mammalian specific proteases including aminopeptidases, trypsin-like and aspartic proteases. An optional EDTA solution is provided for…

  • 4-(2-Aminoethyl) benzenesulfonyl fluoride hydrochloride Specificity: Specific irreversible inhibitor of serine proteases, including chymotrypsin, kallikrein, plasmin, thrombin and trypsin. A stable non-toxic alternative to PMSF. Solubility: Soluble in water Features …

  • SG-Arginine-C™

    G-Biosciences

    SG -Arginine-C ™ endopeptidase (Clostripain, from C. histolyticum ) specifically hydrolyzes the carboxy peptide bond of Arginine. SG -Arginine-C ™ has been modified chemically by a propriety process to render the enzyme resistant to autolysis and stabilize enzymatic activity. In…

  • Calpain inhibitor I; N-[N-(N-Acetyl-L-leucyl)-L-leucyl]-L-norleucine Specificity: Cell permeable peptide aldehyde inhibitor of calpain I and to a lesser extent calpain II. Also inhibits other neutral cysteine proteases, cathepsin B and L and the proteasome. Solubility: Soluble in DMSO or…

  • SG-Lysine-C™

    G-Biosciences

    SG -Lysine-C ™ endopeptidase, from Lysobacter enzymogenes , is a serine protease highly specific in cleaving peptide bonds at the carboxy side of lysine. Highly purified preparations of SG -Lysine-C ™ are chemically modified making the enzyme resistant to autolysis and stabilizing…

  • Etoposide [100mM]

    G-Biosciences

    (4’-demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside], 4’ -(dihydrogen phosphate)) An inhibitor of topoisomerase II. Supplied as 50μl 100mM solution.

  • FOCUS™ ProteaseArrest™ is a ready-to-use, 100X concentrated, broad range protease inhibitor cocktail that is fully compatible with 2D electrophoresis and subsequent mass spectrometry. The protease inhibitor cocktail contains reversible and irreversible inhibitors of serine, cysteine,…

  • SG-Chymotrypsin™

    G-Biosciences

    SG -Chymotrypsin ™ is a serine endopeptidase, which predominantly cleaves peptide bonds on the carboxy side of tyrosine, phenylalanine and tryptophan. In addition, chymotrypsin has a low catalytic activity against the carboxy side of leucine, methionine, alanine, aspartic and glutamic acids.…

  • ProteCEASE™

    G-Biosciences

    ProteCEASE™ is a dry format version of our ProteaseARREST™ for large scale preparative applications and for those who prefer reconstitution prior to use. ProteCEASE™ is a superior general protease inhibitor cocktail that is suitable for purification from mammalian, plant,…

  • Trypsin

    G-Biosciences

    Trypsin is a serine endopeptidase that specifically cleaves peptide bonds on the carboxy side of s-aminoethyl cysteine, arginine and lysine residues. Typically there is little or no cleavage at arginyl-proline and lysyl-proline bonds. This trypsin is purified from bovine pancreas, 1X…

  • Enterokinase (Recombinant) is highly purified recombinant bovine enterokinase obtained from E. Coli. Enterokinase is highly specific serine protease that hydrolysis peptide bond at the carboxyl side of lysine residue preceded by four aspartic acids (FLAG-tag). Enterokinase is used for removal…

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