MP Biomedicals Antibiotics, Antimycotics & Preservatives
MP Biomedicals
MP Biomedicals is a worldwide corporation manufacturing and distributing systems, kits and reagents for the life science research, medical device, biopharma manufacturing and diagnostics markets. Our extensive portfolio and custom services deliver the dependability that research and industrial communities rely on to worry less and discover more. From small scale research to large scale manufacturing, MP Biomedicals has been advancing life science projects for over 50 years.
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Dexamethasone
MP BiomedicalsDexamethasone is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S…
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Tetracycline Hydrochloride
MP BiomedicalsTetracycline is a broad spectrum polyketide antibiotic with clinical uses in treating bacterial infections such as Rocky Mountain spotted fever, typush fever, tick fevers, Q fever, and Brill-Zinsser disease and to treat upper respiratory infections and acne. It has been used in studies of multidrug…
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Tunicamycin from Streptomyces sp.
MP BiomedicalsTunicamycin is a mixture of Tunicamycins A, B, C and D. It is a nucleoside antibiotic active in vitro against Gram-positive bacteria, yeasts, fungi, and viruses. Tunicamycin has been used to study the effect of N-linked glycosylation of human proton-coupled folate transporter (HsPCFT) in HeLa…
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Kanamycin Solution
MP BiomedicalsKanamycin is an aminoglycoside antibiotic effective against mycoplasma, gram-positive and gram-negative bacteria. It is used in biotechnology applications to inhibit protein synthesis. Mode of Action: Binds to 70S ribosomal subunit; inhibits translocation; elicits miscoding. Antimicrobial…
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Cycloheximide
MP BiomedicalsCycloheximide is a glutarimide antibiotic derived from a microbial source. Cycloheximide is an antibiotic which is very active against many molds, yeasts, and phytopathogenic fungi. It exhibits somewhat lower activity against bacteria and certain fungi. Control of various molds and fungi in…
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Amphotericin B
MP BiomedicalsAmphotericin B is a polyene antifungal antibiotic from Streptomyces sp. It has a high affinity for sterols, primarily ergosterols, of fungal and bacterial cell membranes. It is an antibiotic solution effective against yeast and other fungi. Amphotericin B may be toxic to some insect cell types.…
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G418 Sulfate Solution
MP BiomedicalsG418 Sulfate is used as a selective antibiotic in the concentration range of 100 - 200 µg/mL for bacteria, or 200 – 500 µg/mL for most mammalian cells. It is also used for the selection of transfected mammalian cells, yeast, dictyostelium, plant and bacteria. G418 Sulfate is an…
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Indomethacin
MP BiomedicalsIndomethacin, an anti-inflammatory agent, inhibits Cox-1 and Cox-2 (cyclooxygenases) with selectivity for Cox-1 (IC50 of 230 nM) over Cox-2 (IC50 of 630 nM). Additionally, Indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor…
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Nocodazole
MP BiomedicalsApplications Methyl(5-(2-thienylcarbonyl)-1H-benzimidazole-2-yl)carbamate is an anticancer drug that has been shown to interfere with the structure and function of microtubules in interphase and mitotic cells. Malignant cells may be more susceptible to the antimicrotubular effect of nocodazole…
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Nalidixic Acid Sodium Salt
MP BiomedicalsNalidixic acid sodium salt is an antibacterial agent (synthetic quinolone antibiotic), which is inhibitor of bacterial DNA polymerase (DNA gyrase) & avian myeloblastoma virus reverse transcriptase. Inhibits nucleic acid and protein synthesis in Saccharomyces cerevisiae. Typically used at a…
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Penicillin G Potassium Salt
MP BiomedicalsPenicillin G is a narrow spectrum antibiotic. Active against gram-positive and gram-negative aerobic and anaerobic bacteria Inhibits cell wall synthesis Stable against hydrolysis by β-lactamases, such as penicillinases and cephalosporinases The drug of choice for Streptococcus…
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Metronidazole
MP BiomedicalsMetronidazole ia an antiprotozoal (Trichomonas), a limited spectrum antibiotic that actively deters the growth of protozoa, anaerobic gram-positive, and anaerobic gram-negative bacteria. Metronidazole suppress protozoans such as Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis.…
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Penicillin G Potassium Salt
MP BiomedicalsPenicillin G potassium Salt is a salt of Penicillin G. Penicillin G is a hydrophobic, β-lactam antibiotic produced by Penicillium spp. Penicillin G is also known as benzylpenicillin and contains a 6’ phenylacetyl side chain. In acid aqueous solutions, Penicillin is reported to decompose…
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Ampicillin Trihydrate
MP BiomedicalsAmpicillin is a semi-synthetic derivative of penicillin, active as a broad-spectrum antibiotic. It is inactivated by beta-lactamases and for this reason a beta-lactamase inhibitor should be considered when using ampicillin. Against gram-positive bacteria, ampicillin has a similar mode of action as…
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Chlortetracycline Hydrochloride
MP BiomedicalsChlortetracycline hydrochloride has antimicrobial action similar to tetracycline hydrochloride, but it is somewhat less active against many Gram-negative organisms. It was first isolated from the culture of Streptomyces aureofacien. Cell-permeable fluorescent probe for Ca2+ for measuring calcium…
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Sulfanilamide
MP BiomedicalsSulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline. As a sulfonamide antibiotic, it functions by competitively inhibiting (i.e., by acting as a substrate analogue) enzymatic reactions involving para-aminobenzoic acid (PABA). PABA is needed in enzymatic…
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Mycoplasma Removal Agent
MP BiomedicalsApplications Mycoplasma Removal Agent (MRA) eliminates mycoplasma contamination from cell cultures. The cytotoxicity of MRA is low and cell toxicity is rare when used at the recommended concentration. For specific function of any cell, however, it is recommended that the retention of desired…
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TETRACYCLINE, 5 g
MP BiomedicalsTetracyline inhibits gram-positive, gram-negative and mycoplasma. It is used in tetracycline controlled gene expression systems (gene switches) such as the tet-on and tet-off systems. It is also used to select tetracyline resistant colonies in cell culture.
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Actinonin
MP BiomedicalsProduct Description Antibiotic. Aminopeptidase M, N and leucine and alanine aminopeptidase inhibitor. Potent peptide deformylase (PDF) inhibitor. Inhibits MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-12 and MMP-13, but not MMP-14. Anticancer compound. Antiproliferative. Shows antitumor…
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Gentamicin Sulfate
MP BiomedicalsGentamicin is an aminoglycoside antibiotic complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is a mixture of 3 major components designated as C1, C1a, and C2. Gentamicin is used as the sulfate salt. Each component consists of five basic nitrogens and requires five…
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Valinomycin
MP BiomedicalsA metabolite with a broad antibiotic spectrum. Inhibitor of mitochonclrial action. K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes…
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Tamoxifen Citrate Salt
MP BiomedicalsProtein Kinase C inhibitor. Tamoxifen Citrate Salt is a nonsteroidal triphenylethylene derivative. Tamoxifen and its metabolite 4-hydroxytamoxifen are mixed estrogen agonists/antagonists. Tamoxifen has been shown to protect bone from estrogen-deficiency bone loss and lower plasma cholesterol in…
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Pyrimethamine
MP BiomedicalsPyrimethamine is a diamino-pyrimidine and folic acid antagonist. Pyrimethamine is a medication used for protozoal infections. It is commonly used as an antimalarial drug, and is also used (combined with sulfadiazine) in the treatment of Toxoplasma gondii infections in immunocompromised patients,…
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Chlorhexidine Digluconate Solution
MP BiomedicalsChlorhexidine digluconate, a bis(biguanide) family cationic broad spectrum antibiotic is an antiseptic and disinfectant agent. It is effective against a wide range of bacteria, some fungi and some viruses, and an agent for the prevention of gingivitis. Chlorhexidine digluconate solution inhibits…
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Amoxicillin
MP BiomedicalsAmoxicillin is an antibacterial agent against gram-positive and gram-negative bacteria. Amoxicillin is a moderate-spectrum, β-lactam antibiotic. Amoxicillin is one of the most common antibiotics prescribed for children. It is used to study the oxygen dependent antimicrobial systems of…
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Ofloxacin
MP BiomedicalsOfloxacin is a synthetic fluoroquinolone with broad-spectrum antibacterial activity. It is a nalidixic acid analog. Ofloxacin is used to study pneumococcal cell wall-degrading virulence factors. Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, which haults DNA replication and…
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Actinomycin D from Streptomyces parvalus
MP BiomedicalsActinomycin D is a polypeptide antibiotic first described by Waksman. It is bacteriostatic in nature, especially towards gram negative bacteria, and also has anti-tumor activity. Actinomycin D has a wide-ranging applications ranging from a selection agent in cell culture, use in studies of…
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Rapamycin
MP BiomedicalsRapamycin is a member of the macrolide immunosuppressant family and a FRAP inhibitor. Rapamycin is unique in its ability to inhibit lymphokine induced cell proliferation at the G1 and S phase as well as an irreversible cellular arrest at the G1 phase in S. cerevisiae cells. It also exhibits…
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Polymyxin B Sulfate
MP BiomedicalsPolymyxin B Sulfate is a mixture of Polymyxin B1 and Polymyxin B2 Sulfate, obtained from Bacillus polymyxia strains. Polymyxin B inhibits gram-negative organisms in vitro and is also reported to inhibit Ca2+ dependent protein kinase C (PKC). It binds to and interferes with the permeability of the…
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Herbimycin A
MP BiomedicalsBenzoquinone ansamycin antibiotic. Herbicidal compound. Potent, selective, irreversible and cell permeable protein tyrosine kinase inhibitor. Inhibitor of v-Src, Yes, Fps, Ros, Bcr-Abl and ErbB oncogene products. Antitumor compound. Antiangiogenic. Inhibits NF-kappaB activation and phosphorylation…
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Gentamicin Sulfate
MP BiomedicalsGentamicin sulpahte is an aminoglycoside antibiotic complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is a mixture of 3 major components designated as C1, C1a, and C2. Gentamicin is used as the sulfate salt. Each component consists of five basic nitrogens and…
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(+)-Aphidicolin
MP BiomedicalsProduct Description Phytotoxin. Antibiotic. Antiviral and antineoplastic agent. Antileishmanial agent. Reversible inhibitor of eukaryotic nuclear DNA replication. Useful for cell synchronization. Blocks the cell cycle at G1/S phase. Prolongs the half life of DNA methyltransferase. DNA…