Ofloxacin is a synthetic fluoroquinolone with broad-spectrum antibacterial activity. It is a nalidixic acid analog.
Ofloxacin is used to study pneumococcal cell wall-degrading virulence factors.
Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, which haults DNA replication and cell division. Ofloxacin has been shown to convert LytA from the inactive E-form to the active C-form. It is a chiral molecule that inhibits pneumococcal cell wall-degrading virulence factors.
Key Applications: Anti-bacterial Agent
Product Type: Biochemicals
Biochemical Category: Antibiotics
Chemical Class: Antibiotics
Optical Rotation: +1 to -1°(Lit.)
Presentation: White Powder
Format: Powder
Solubility: Soluble in 1 N NaOH(50 mg/mL).
Storage & Handling: Store at Room Temperature (15-30°C).