Inhibitor of bacterial cell wall synthesis. Active against gram positive and some gram negative bacteria. B-Lactamase sensitive.

Staurosporin is an antibiotic which is isolated from Streptomyces species, possesses inhibitory activity against fungi and yeasts. It is potent inhibitor of phospolipid/Ca2+ dependent and cyclic nucleotide dependent protein kinases, a potent protein kinase inhibitor useful as a tool for studies on…

Amphotericin B is used to prevent the contamination of cell cultures by yeast and multicellular fungi. 100X concentration. Just dilute 1:100 to get the final working concentration of 2.50 µg/mL Antifungal agent Amphotericin B prevents the growth of fungi by causing an increase in fungal…

Fluconazole is a subclass of the synthetic triazole antifungal agents. A highly selective inhibitor of fungal cytochrome P-450 sterol C-14 a-demethylation. Fluconazole is a potent inhibitor of CYP2C9. Fluconazole interferes with fungal ergosterol synthesis and downregulates the metallothionein gene.

MOLECULAR BIOLOGY GRADE   Gentamicin efficiently inhibits growth of many Gram-positive and Gram-negative microorganisms. It does so by inhibiting protein synthesis by binding to the L6 protein of the 30S ribosomal subunit. It is also effective against mycoplasma. Recommended for use in…

Indomethacin, an anti-inflammatory agent, inhibits Cox-1 and Cox-2 (cyclooxygenases) with selectivity for Cox-1 (IC50 of 230 nM) over Cox-2 (IC50 of 630 nM). Additionally, Indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor…

Cell culture tested. Aminoglycoside antibiotic with bactericidal activity against most gram negative bacteria.

Applications Mycoplasma Removal Agent (MRA) eliminates mycoplasma contamination from cell cultures. The cytotoxicity of MRA is low and cell toxicity is rare when used at the recommended concentration. For specific function of any cell, however, it is recommended that the retention of desired…

Active against gram negative bacteria. Potency approximately 20,000 units per milligram.

Plant cell culture tested. Polyene antifungal antibiotic produced by Streptomyces nodosus . Interferes with the permeability of cell wall membrane of sensitive fungi and yeasts by binding to sterols.

Used as an antiprotozoal, antibacteria, or antifungal agent. Monensin is an ionophore which disrupts the structure of the Golgi apparatus and inhibits vesicular transport in eukaryotic cells.

Anisomycin, also known as flagecidin, is an antibiotic produced by Streptomyces griseolus which inhibits protein synthesis.

Aminoglycoside antibiotic used as a selective agent in transformation experiments. Alternative for Kanamycin in monocots eg: rice, lollum and graminea which are highly resistant to the latter. Optical rotation +121.2°. Cell culture tested on Bacillus subtilus .

Inhibitor of bacterial cell wall synthesis resulting in lysis or deformation of the bacterium. Inhibits crosslinking of peptidoglycan by binding and inactivating transpeptidases. Highly active against gram negative bacteria. B-Lactamase sensitive. Plant cell culture tested. Widely used as a…

Interferes with bacterial cell wall synthesis by competing with D-Alanine for incorporation into the cell wall. Active against most mycobacteria with some activity against gram negative bacteria.

Polyene antifungal antibiotic produced by Streptomyces noursei.

Gentamicin is an aminoglycoside complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is used as the sulfate salt. Ready-to-use solution Applications Gentamicin acts by binding to the 30S subunit of the bacterial ribosome leading to inhibition protein synthesis and…

Synonyms: Pen-Strep Storage: -20C UNSPSC Code: 51101500 General description: Penicillin Streptomycin solution, also known as Pen Strep, is the most commonly used antibiotic solution for the culture of mammalian cells. Penicillin Streptomycin solution is used to maintain sterile conditions…

Gentamicin sulpahte is an aminoglycoside antibiotic complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is a mixture of 3 major components designated as C1, C1a, and C2. Gentamicin is used as the sulfate salt. Each component consists of five basic nitrogens and…

Glycopeptide antibiotic that inhibits formation of peptidoglycan polymers of the bacterial cell wall. Differs from penicillins that act primarily to prevent the crosslinking of peptidoglycans. Vancomycin prevents the transfer and addition of the muramylpentapeptide building blocks that form the…

Amphotericin B, Penicilllin, Stretomycin Mix is useful for reducing the chance of microbial contamination. Convenient mixture of the antibiotics and antifungal agent in one bottle. 100X concentration, just dilute 1:100 in the culture medium Recommended for use in cell culture applications at…

Dexamethasone is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S…