Lidocaine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Lidocaine is also an anasthetic and class Ib antiarrhythmic agent. This compund is known to block voltage-gated sodium channels in the inactivated state. Lidocaine is a second-generation…

Glycerol is a simple polyol compound. Glycerol is used both in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol (5-10%) increases the density of a sample so that the sample will layer at the bottom of a gel’s sample well. Glycerol is also used to aid…

Xylenes are aromatic hydrocarbons. Xylene is used as a solvent. It is used in the laboratory to make baths with dry ice to cool reaction vessels, and as a solvent to remove synthetic immersion oil from the microscope objective in light microscopy.

A mineral oil is any of various colorless, odorless, light mixtures of alkanes in the C15 to C40 range from a non-vegetable (mineral) source, particularly a distillate of petroleum.Most often, mineral oil is a liquid by-product of the distillation of petroleum to produce gasoline and other…

Sodium phosphate is a reagent with very high buffering capacity that is widely used in molecular biology, biochemistry, and chromatography. Sodium phosphate occurs in several forms: monobasic (NaH₂PO₄), dibasic (Na₂HPO₄), and tribasic…

Potassium phosphate is a reagent with high buffering capacity. It occurs in several forms: monobasic, dibasic and tribasic. Most pH neutral potassium phosphate buffer solutions consist of mixtures of the monobasic and dibasic forms to varying degrees, depending on the desired pH. Potassium…

Bromelain is a cysteine endopeptidase with broad specificity for cleavage of proteins. Bromelain may be from a stem or piece of fruit. Glycoprotein which is a highly active thiol proteinase Non-specific cysteine protease Splits glycine esters but not lysine esters Protein digesting…

p-Toluenesulfonic acid monohydrate is an organic-soluble acid catalyst in organic synthesis. The catalyst has been incorporated in the esterification of carboxylic acids or transesterification of esters. p-Toluenesulfonic acid monohydrate has been used as a reducing agent for the reductive…

Salicin is a substrate for β-glucosidase.

Hexamethylenetetramine is a tetraamine compound with a structure analogous to adamantane. Hexamethylenetetramine is used for amino acid preparation. It is also used in synthesis as a formylation agent and is employed in preparing specialized materials. It is also used as a precipitating agent. …

Anhydrous, ACS reagent grade, White Crystalline Powder

5-Bromo-2’-deoxyuridine is a thymidine analog and useful for the study of DNA synthesis where it is incorporated into DNA in place of thymidine. Measure DNA synthesis Label dividing cells Study cell signaling and processes that induce cell proliferation Used as a mutagen in…

Dexamethasone is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S…

p-Iodonitrotetazolium Violet is used as a electron acceptor for the colorimetric assay of various dehydrogenases.

Methionine is one of the common sulfur-containing amino acids. Methionine is a common methyl-group donor to various substrates, such as creatine, epinephrine, ergosterol, and choline. L-Methionine is used as an essential amino acid for human development and therapeutically acts as an antidote…

Propylene glycol is a clear, colorless and hygroscopic liquid. Propylene glycol contains an asymmetrical carbon atom, so it exists in two stereoisomers. The freezing point of water is depressed when mixed with propylene glycol due to increased opportunity for hydrogen bonding. Propylene glycol…

Cycloheximide is a glutarimide antibiotic derived from a microbial source. Cycloheximide is an antibiotic which is very active against many molds, yeasts, and phytopathogenic fungi. It exhibits somewhat lower activity against bacteria and certain fungi. Control of various molds and fungi in…

Polyvinyl alcohol (PVOH, PVA, or PVAl) is a water-soluble synthetic polymer. Polyvinyl alcohol is the raw material to make polymers. Polyvinyl alcohol is used as an emulsion polymerization aid, as protective colloid, to make polyvinyl acetate dispersions.

Ampicillin is a semi-synthetic derivative of penicillin, active as a broad-spectrum antibiotic. It is inactivated by beta-lactamases and for this reason a beta-lactamase inhibitor should be considered when using ampicillin. Against gram-positive bacteria, ampicillin has a similar mode of action as…

Erythromycin is a macrolide antibiotic that bind to the 50S ribosomal subunit and inhibit protein synthesis. This is an antimicrobial substance produced by the growth of certain strains of Streptomyces erythreus. It is a mixture consisting largely of erythromycin A with lesser amounts of…

Metronidazole ia an antiprotozoal (Trichomonas), a limited spectrum antibiotic that actively deters the growth of protozoa, anaerobic gram-positive, and anaerobic gram-negative bacteria. Metronidazole suppress protozoans such as Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis.…

Tween 80 is a polyethylene sorbitol ester, non ionic surfactant and an emulsifier derived from polyethoxylated sorbitan and oleic acid. Tween 80 has been widely used in biochemical applications including: solubilizing proteins, isolating nuclei from cells in culture, growing of tubercule…

Pullulan, edible plastic excellent in adhesivenss and film formability. Pullulan is a natural neutral polysaccharide produced from starch by cultivating a black yeast. Pullulan has been used in a study to assess bone tissue engineering. It has also been used in a study that investigated anti-fog applications.

Polysorbate-20 is a nonionic surfactants derived from sorbitan esters. Polysorbate 20 is used as an emulsifying agent for the preparation of stable oil-inwater emulsions in pharmaceuticals, cosmetics, and cleaning compounds. Polysorbate 20 has been used in preextraction of membranes to remove…

Spermidine is biogenic polyamine formed from putrescine, a precursor of spermine. Spermidine has a role in cell growth processes and the formation and interconversion of spermidine in mammalian cells has been reported. Spermidine binds to and activates NMDA(N-Methyl-D-Aspartate receptor) and has…

Pepsin, an acid protease, contains a proteolytic enzyme. Pepsin contains the "cathepsin" component which has milk curdling activity. It has a broad range of substrate activity and demonstrates an esterase acitivity. It generally attacks peptide bonds. Pepsin is a peptidase used to…

Mitomycin C is the most widely used of the Mitomycin antibiotics because it is the least toxic and with the most potent antitumor activity. Inhibitor of DNA synthesis, nuclear division, and cancer cells. Antibacterial to gram positive, gram negative, acid-fast bacilli. Mitomycin C…

Oleic acid is a mono-unsaturated omega-9 fatty acid created by dehydrogenation of stearic acid. It is then further dehydrogenated and elongated to create members of the n-9 family of fatty acids. Oleic acid is used as emollient. Small amounts of oleic acid are used as an excipient in…

Sodium Orthovanadate is a potent alkaline phosphate inhibitor. Sodium Orthovanadate is used in the diabetes study. Sodium orthovandate was used to prepare the stop solution in dephosphorylation assay of insulin receptor kinase. It was one of the reagents used in the development of Matrix ChIP…

Vitamin K is a group of structurally similar, fat-soluble vitamins. Vitamin K1 is used as a cofactor in the formation of coagulation factors II (prothrombin), VII, IX and X; anticoagulant factors protein C and S and as a cell signaling factor.

Sodium metabisulfite is an antioxidant reducing agent, with antimicrobial and antifungal properties. Gastric tissue studies report that sodium metabisulfite can augment lipid peroxidation and apoptosis in a dose-dependent manner. Sodium metabisulfite is used as an active ingredient in campden…

Dimethyl Sulfoxide is a dipolar, aprotic solvent. It has been shown to accelerate strand renaturation (1-10% concentration) and is believed to give the nucleic acid thermal stability against depurination. Dimethyl Sulfoxide is used to enhance dermal absorption of many chemicals, as a solvent for…