Spermidine is biogenic polyamine formed from putrescine, a precursor of spermine. Spermidine has a role in cell growth processes and the formation and interconversion of spermidine in mammalian cells has been reported. Spermidine binds to and activates NMDA(N-Methyl-D-Aspartate receptor) and has been shown to potentiate NMDA-induced currents in a concentration-dependent manner.
Spermidine binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity. It has a role in cell growth processes. It can be used in electroporation while transferring the DNA into the cell under the electrical impulse. It is also plant growth regulator, promoting somatic embryogenesis.
Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.
Key Applications: Purification of DNA-binding proteins, Plant growth regulator, Electroporation
Application Areas: Cell Biology & Analysis
Product Type: Biochemicals
Density: 0.925 g/mL
Boiling Point: 128-130°C
Refractive Index: 1.479 (20°C)(Lit.)
Presentation: Colorless to White Waxy Solid
Solubility: Soluble in water, ethanol, ether.
Sterilization of Solutions: Solutions should be sterile-filtered, not autoclaved.
Storage & Handling: Store at +4°C, desiccate.