MP Biomedicals Antibiotics, Antimycotics & Preservatives
MP Biomedicals
MP Biomedicals is a worldwide corporation manufacturing and distributing systems, kits and reagents for the life science research, medical device, biopharma manufacturing and diagnostics markets. Our extensive portfolio and custom services deliver the dependability that research and industrial communities rely on to worry less and discover more. From small scale research to large scale manufacturing, MP Biomedicals has been advancing life science projects for over 50 years.
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Kanamycin Monosulfate from Streptomyces kanamycetikus
MP BiomedicalsKanamycin sulfate is an antimicrobial agent effective against Gram-negative and Gram-positive bacteria and mycoplasma. It binds to the 70S ribosomal subunit, inhibits translocation, and elicits miscoding. Cross-resistance occurs between kanamycin and neomycin, framycetin, and paromomycin, and…
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Blasticidin S Hydrochloride, Phytopure™, 250 mg
MP BiomedicalsBroad spectrum nucleoside antibiotic. Inhibits protein synthesis in prokaryotic and eukaryotic organisms. Suitable for selection of cells carrying plasmids conferring blasticidin resistance. Blasticidin S inhibits hydrolysis of peptidyl-tRNA induced by release factors. It enhances the binding of…
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MCC950 Na
MP BiomedicalsProduct Description Potent, selective and orally available NLRP3 inflammasome inhibitor. Blocks the release of IL-1beta in macrophages primed with LPS and activated with ATP or nigericin, but it does not inhibit NLRP1, NLRC4, AIM2, TLR2 signaling or priming of NLRP3. Prevents…
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Cefoperazone Sodium Salt
MP BiomedicalsCefoperazone sodium salt is a broad spectrum third generation cephalosporin antibiotic that has similar antimicrobial activity to ceftazidime. It is active against Pseudomonoas aeruginosa and it has enhanced activity against Enterobacteriaceae and Bacteroides sp. in the presence of the…
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G418 Sulfate
MP BiomedicalsProduct Description Antibiotic. Cytotoxic to prokaryotic and eukaryotic cells by inhibiting the protein synthesis. Apoptosis inducer. Widely employed in the selection of eukaryotic expression vectors, in combination with either aminoglycoside phosphotransferase 3' or APH II. Antiviral. …
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Chloroquine Diphosphate Salt
MP BiomedicalsChloroquine Diphosphate salt is a member of the quinolone family and a lysosomotropic agent (accumulate inside the acidic parts of the cell). This accumulation leads to inhibition of lysosomal enzymes that require an acidic pH, and prevents fusion of endosomes and lysosomes. Chloroquine…
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Staurosporine from Streptomyces species
MP BiomedicalsStaurosporin is an antibiotic which is isolated from Streptomyces species, possesses inhibitory activity against fungi and yeasts. It is potent inhibitor of phospolipid/Ca2+ dependent and cyclic nucleotide dependent protein kinases, a potent protein kinase inhibitor useful as a tool for studies on…
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Spectinomycin is an aminocyclitol antibiotic, closely related to the aminoglycosides, it inhibits protein synthesis (elongation) by interfering with peptidyl tRNA translocation. Mutation in rpsE (the gene for ribosomal protein S5) prevents binding of spectinomycin. Specinomycin is used in cell…
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Tamoxifen
MP BiomedicalsTamoxifen is a Protein Kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in…
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G418 Disulfate, Phytopure™
MP BiomedicalsG418 is an aminoglycoside related to Gentamicin and is toxic to bacteria, yeast, higher plants, mammalian cells, protozoans and helminths. It blocks polypeptide synthesis in both prokaryotic and eukaryotic cells and is useful for selection of genetically engineered eukarytoic cells in culture.
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TETRACYCLINE, 5 g
MP BiomedicalsTetracyline inhibits gram-positive, gram-negative and mycoplasma. It is used in tetracycline controlled gene expression systems (gene switches) such as the tet-on and tet-off systems. It is also used to select tetracyline resistant colonies in cell culture.
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Penicillin G Potassium Salt
MP BiomedicalsPenicillin G potassium Salt is a salt of Penicillin G. Penicillin G is a hydrophobic, β-lactam antibiotic produced by Penicillium spp. Penicillin G is also known as benzylpenicillin and contains a 6’ phenylacetyl side chain. In acid aqueous solutions, Penicillin is reported to decompose…
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Metronidazole
MP BiomedicalsMetronidazole ia an antiprotozoal (Trichomonas), a limited spectrum antibiotic that actively deters the growth of protozoa, anaerobic gram-positive, and anaerobic gram-negative bacteria. Metronidazole suppress protozoans such as Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis.…
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Rifamycin SV Sodium Salt
MP BiomedicalsRifamycin SV is a broad-spectrum semisynthetic antimicrobial agent of the rifamycin group. Rifamycin SV is used to study potential genes, such as rif15 and rif16, which may be involved in the conversion of rifamycin SV into rifamycin B. It is a potential treatment for traveler’s diarrhea…
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Dexamethasone
MP BiomedicalsDexamethasone is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S…
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Cycloheximide from Microbial
MP BiomedicalsCycloheximide is an antibiotic which is very active against many molds, yeasts, and phytopathogenic fungi. Inhibits peptide synthesis in eukaryotic organisms Used in protein synthesis in apoptosis Study of disease resistance in plant research Cycloheximide (CHX) is an antibiotic…
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Tetracycline Hydrochloride
MP BiomedicalsTetracycline is a broad spectrum polyketide antibiotic with clinical uses in treating bacterial infections such as Rocky Mountain spotted fever, typush fever, tick fevers, Q fever, and Brill-Zinsser disease and to treat upper respiratory infections and acne. It has been used in studies of multidrug…
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Fluconazole
MP BiomedicalsFluconazole is a subclass of the synthetic triazole antifungal agents. A highly selective inhibitor of fungal cytochrome P-450 sterol C-14 a-demethylation. Fluconazole is a potent inhibitor of CYP2C9. Fluconazole interferes with fungal ergosterol synthesis and downregulates the metallothionein gene.
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Actinonin
MP BiomedicalsProduct Description Antibiotic. Aminopeptidase M, N and leucine and alanine aminopeptidase inhibitor. Potent peptide deformylase (PDF) inhibitor. Inhibits MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-12 and MMP-13, but not MMP-14. Anticancer compound. Antiproliferative. Shows antitumor…
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Gentamicin Sulfate
MP BiomedicalsGentamicin is an aminoglycoside antibiotic complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is a mixture of 3 major components designated as C1, C1a, and C2. Gentamicin is used as the sulfate salt. Each component consists of five basic nitrogens and requires five…
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Valinomycin
MP BiomedicalsA metabolite with a broad antibiotic spectrum. Inhibitor of mitochonclrial action. K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes…
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Tamoxifen Citrate Salt
MP BiomedicalsProtein Kinase C inhibitor. Tamoxifen Citrate Salt is a nonsteroidal triphenylethylene derivative. Tamoxifen and its metabolite 4-hydroxytamoxifen are mixed estrogen agonists/antagonists. Tamoxifen has been shown to protect bone from estrogen-deficiency bone loss and lower plasma cholesterol in…
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Pyrimethamine
MP BiomedicalsPyrimethamine is a diamino-pyrimidine and folic acid antagonist. Pyrimethamine is a medication used for protozoal infections. It is commonly used as an antimalarial drug, and is also used (combined with sulfadiazine) in the treatment of Toxoplasma gondii infections in immunocompromised patients,…
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Chlorhexidine Digluconate Solution
MP BiomedicalsChlorhexidine digluconate, a bis(biguanide) family cationic broad spectrum antibiotic is an antiseptic and disinfectant agent. It is effective against a wide range of bacteria, some fungi and some viruses, and an agent for the prevention of gingivitis. Chlorhexidine digluconate solution inhibits…
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Amoxicillin
MP BiomedicalsAmoxicillin is an antibacterial agent against gram-positive and gram-negative bacteria. Amoxicillin is a moderate-spectrum, β-lactam antibiotic. Amoxicillin is one of the most common antibiotics prescribed for children. It is used to study the oxygen dependent antimicrobial systems of…
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Ofloxacin
MP BiomedicalsOfloxacin is a synthetic fluoroquinolone with broad-spectrum antibacterial activity. It is a nalidixic acid analog. Ofloxacin is used to study pneumococcal cell wall-degrading virulence factors. Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, which haults DNA replication and…
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Actinomycin D from Streptomyces parvalus
MP BiomedicalsActinomycin D is a polypeptide antibiotic first described by Waksman. It is bacteriostatic in nature, especially towards gram negative bacteria, and also has anti-tumor activity. Actinomycin D has a wide-ranging applications ranging from a selection agent in cell culture, use in studies of…
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Rapamycin
MP BiomedicalsRapamycin is a member of the macrolide immunosuppressant family and a FRAP inhibitor. Rapamycin is unique in its ability to inhibit lymphokine induced cell proliferation at the G1 and S phase as well as an irreversible cellular arrest at the G1 phase in S. cerevisiae cells. It also exhibits…
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Polymyxin B Sulfate
MP BiomedicalsPolymyxin B Sulfate is a mixture of Polymyxin B1 and Polymyxin B2 Sulfate, obtained from Bacillus polymyxia strains. Polymyxin B inhibits gram-negative organisms in vitro and is also reported to inhibit Ca2+ dependent protein kinase C (PKC). It binds to and interferes with the permeability of the…
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Herbimycin A
MP BiomedicalsBenzoquinone ansamycin antibiotic. Herbicidal compound. Potent, selective, irreversible and cell permeable protein tyrosine kinase inhibitor. Inhibitor of v-Src, Yes, Fps, Ros, Bcr-Abl and ErbB oncogene products. Antitumor compound. Antiangiogenic. Inhibits NF-kappaB activation and phosphorylation…
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Gentamicin Sulfate
MP BiomedicalsGentamicin sulpahte is an aminoglycoside antibiotic complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is a mixture of 3 major components designated as C1, C1a, and C2. Gentamicin is used as the sulfate salt. Each component consists of five basic nitrogens and…
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(+)-Aphidicolin
MP BiomedicalsProduct Description Phytotoxin. Antibiotic. Antiviral and antineoplastic agent. Antileishmanial agent. Reversible inhibitor of eukaryotic nuclear DNA replication. Useful for cell synchronization. Blocks the cell cycle at G1/S phase. Prolongs the half life of DNA methyltransferase. DNA…