Chlortetracycline hydrochloride has antimicrobial action similar to tetracycline hydrochloride, but it is somewhat less active against many Gram-negative organisms. It was first isolated from the culture of Streptomyces aureofacien. Cell-permeable fluorescent probe for Ca2+ for measuring calcium…

Kanamycin sulfate is an antimicrobial agent effective against Gram-negative and Gram-positive bacteria and mycoplasma. It binds to the 70S ribosomal subunit, inhibits translocation, and elicits miscoding. Cross-resistance occurs between kanamycin and neomycin, framycetin, and paromomycin, and…

Spectinomycin sulfate is an antibiotic which binds to the 30S subunit to cause misreading. Spectinomycin sulfate is a broad spectrum antibiotic that inhibits protein synthesis (elongation) by binding to the bacterial 30S ribosomal subunit and interfering with peptidyl tRNA translocation.

Hygromycin B is an antibiotic substance isolated from Streptomyces hygroscopicus. Its mode of action is the inhibition of protein synthesis, by inducing the misreading of the m-RNA template in the prokaryote, (E. coli, at 100 mg/mL), lower eukaryotes (e.g., yeast, at 200 mg/mL) and higher…

Ivermectin is a macrolide antiobiotic, & semisynthetic derivative of avermectin B1a and B1b. Ivermectin is a broad-spectrum antiparasitic agent. Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptor; also modulates glutamate-GABA-activated chloride channels.

Polymyxin B Sulfate is a mixture of Polymyxin B1 and Polymyxin B2 Sulfate, obtained from Bacillus polymyxia strains. Polymyxin B inhibits gram-negative organisms in vitro and is also reported to inhibit Ca2+ dependent protein kinase C (PKC). It binds to and interferes with the permeability of the…

Protein Kinase C inhibitor. Tamoxifen Citrate Salt is a nonsteroidal triphenylethylene derivative. Tamoxifen and its metabolite 4-hydroxytamoxifen are mixed estrogen agonists/antagonists. Tamoxifen has been shown to protect bone from estrogen-deficiency bone loss and lower plasma cholesterol in…

Chloroquine Diphosphate salt is a member of the quinolone family and a lysosomotropic agent (accumulate inside the acidic parts of the cell). This accumulation leads to inhibition of lysosomal enzymes that require an acidic pH, and prevents fusion of endosomes and lysosomes. Chloroquine…

Applications Mycoplasma Removal Agent (MRA) eliminates mycoplasma contamination from cell cultures. The cytotoxicity of MRA is low and cell toxicity is rare when used at the recommended concentration. For specific function of any cell, however, it is recommended that the retention of desired…

Tetracycline is a broad spectrum polyketide antibiotic with clinical uses in treating bacterial infections such as Rocky Mountain spotted fever, typush fever, tick fevers, Q fever, and Brill-Zinsser disease and to treat upper respiratory infections and acne. It has been used in studies of multidrug…

Amphotericin B is used as antifungal in cell culture media. Amphotericin B is a polyene antifungal antibiotic from Streptomyces sp. It has a high affinity for sterols, primarily ergosterols, of fungal and bacterial cell membranes. It is an antibiotic solution effective against yeast and other…

Chlorhexidine digluconate, a bis(biguanide) family cationic broad spectrum antibiotic is an antiseptic and disinfectant agent. It is effective against a wide range of bacteria, some fungi and some viruses, and an agent for the prevention of gingivitis. Chlorhexidine digluconate solution inhibits…

An antiseptic and disinfectant agent. It is effective against a wide range of bacteria, some fungi and some viruses, and an agent for the prevention of gingivitis. Commercial ophthalmic products have used this agent to replace thimerosal as a preservative; however, it can cause skin irritation. …

Streptomycin Sulfate is an aminoglucoside antibiotic in which streptidine is linked glycosidically to the disaccharide streptobiosamine. Inhibit bacterial protein synthesis Gram positive bacteria Gram negative bacteria Mode of Action: Inhibits prokaryote protein synthesis. Binds to…

Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline. As a sulfonamide antibiotic, it functions by competitively inhibiting (i.e., by acting as a substrate analogue) enzymatic reactions involving para-aminobenzoic acid (PABA). PABA is needed in enzymatic…

Gentamicin is an aminoglycoside antibiotic complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is a mixture of 3 major components designated as C1, C1a, and C2. Gentamicin is used as the sulfate salt. Each component consists of five basic nitrogens and requires five…

Erythromycin is a macrolide antibiotic that bind to the 50S ribosomal subunit and inhibit protein synthesis. This is an antimicrobial substance produced by the growth of certain strains of Streptomyces erythreus. It is a mixture consisting largely of erythromycin A with lesser amounts of…

Amphotericin B is an antimicrobial/antifungal agent effective against yeast and other fungi. It is a mixture of polyenes. It interrupts cell membrane permeability by binding sterols resulting in the loss of low molecular weight compounds from the cell. Amphotericin B may be toxic to some insect…

Gentamicin sulpahte is an aminoglycoside antibiotic complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is a mixture of 3 major components designated as C1, C1a, and C2. Gentamicin is used as the sulfate salt. Each component consists of five basic nitrogens and…

Penicillin G is a narrow spectrum antibiotic. Active against gram-positive and gram-negative aerobic and anaerobic bacteria Inhibits cell wall synthesis Stable against hydrolysis by β-lactamases, such as penicillinases and cephalosporinases The drug of choice for Streptococcus…

Penicillin G potassium Salt is a salt of Penicillin G. Penicillin G is a hydrophobic, β-lactam antibiotic produced by Penicillium spp. Penicillin G is also known as benzylpenicillin and contains a 6’ phenylacetyl side chain. In acid aqueous solutions, Penicillin is reported to decompose…

Cycloheximide is a glutarimide antibiotic derived from a microbial source. Cycloheximide is an antibiotic which is very active against many molds, yeasts, and phytopathogenic fungi. It exhibits somewhat lower activity against bacteria and certain fungi. Control of various molds and fungi in…

Aztreonam is the first totally synthetic monocyclic β-lactam antibiotic that displays a high degree of resistance to β-lactamase degradation. It has high specificity for gram-negative aerobic rods. Aztreonam specifically targets the penicillin binding protein 3 (PBP-3) of Gram-negative…

Cycloheximide is an antibiotic which is very active against many molds, yeasts, and phytopathogenic fungi. Inhibits peptide synthesis in eukaryotic organisms Used in protein synthesis in apoptosis Study of disease resistance in plant research Cycloheximide (CHX) is an antibiotic…

Gentamicin Sulfate is a bactericidal antibiotic of the aminoglycoside group produced by fermentation of Micromonospora purpurea or M. echinospora. It is a mixture of 3 major components designated as C1, C1a, and C2. Gentamicin is used as the sulfate salt. Each component consists of five basic…

Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation. Protein kinase C inhibitor (IC50 = 50-200 µM depending on assay conditions in MCF-7 cells or…

Amoxicillin is an antibacterial agent against gram-positive and gram-negative bacteria. Amoxicillin is a moderate-spectrum, β-lactam antibiotic. Amoxicillin is one of the most common antibiotics prescribed for children. It is used to study the oxygen dependent antimicrobial systems of…

Ofloxacin is a synthetic fluoroquinolone with broad-spectrum antibacterial activity. It is a nalidixic acid analog. Ofloxacin is used to study pneumococcal cell wall-degrading virulence factors. Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, which haults DNA replication and…

Kanamycin is an aminoglycoside antibiotic effective against mycoplasma, gram-positive and gram-negative bacteria. It is used in biotechnology applications to inhibit protein synthesis. Mode of Action: Binds to 70S ribosomal subunit; inhibits translocation; elicits miscoding. Antimicrobial…

G418 Sulfate is used as a selective antibiotic in the concentration range of 100 - 200 µg/mL for bacteria, or 200 – 500 µg/mL for most mammalian cells. It is also used for the selection of transfected mammalian cells, yeast, dictyostelium, plant and bacteria. G418 Sulfate is an…

This triple antibiotic solution contains penicillin (10,000 IU/mL), streptomycin (10 mg/mL), and amphotericin B (25 μg/mL). Applications Penicllin-Streptomycin-Amphotericin B is used to supplement cell culture media. It is effective against yeast, fungi, gram-positive and gram-negative…

Product Description Antibiotic. Aminopeptidase M, N and leucine and alanine aminopeptidase inhibitor. Potent peptide deformylase (PDF) inhibitor. Inhibits MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-12 and MMP-13, but not MMP-14. Anticancer compound. Antiproliferative. Shows antitumor…