Antibiotics, Antimycotics & Preservatives
MP Biomedicals
MP Biomedicals is a worldwide corporation manufacturing and distributing systems, kits and reagents for the life science research, medical device, biopharma manufacturing and diagnostics markets. Our extensive portfolio and custom services deliver the dependability that research and industrial communities rely on to worry less and discover more. From small scale research to large scale manufacturing, MP Biomedicals has been advancing life science projects for over 50 years.
-
Mycoplasma Removal Agent
MP BiomedicalsApplications Mycoplasma Removal Agent (MRA) eliminates mycoplasma contamination from cell cultures. The cytotoxicity of MRA is low and cell toxicity is rare when used at the recommended concentration. For specific function of any cell, however, it is recommended that the retention of desired…
-
TETRACYCLINE, 5 g
MP BiomedicalsTetracyline inhibits gram-positive, gram-negative and mycoplasma. It is used in tetracycline controlled gene expression systems (gene switches) such as the tet-on and tet-off systems. It is also used to select tetracyline resistant colonies in cell culture.
-
Dexamethasone
MP BiomedicalsDexamethasone is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S…
-
Polymyxin B Sulfate
MP BiomedicalsPolymyxin B Sulfate is a mixture of Polymyxin B1 and Polymyxin B2 Sulfate, obtained from Bacillus polymyxia strains. Inhibits gram-negative organisms in vitro Binds to and interferes with permeability of bacterial cytoplasmic membrane Inhibits Ca2+ dependent protein kinase C (PKC) …
-
Indomethacin
MP BiomedicalsIndomethacin, an anti-inflammatory agent, inhibits Cox-1 and Cox-2 (cyclooxygenases) with selectivity for Cox-1 (IC50 of 230 nM) over Cox-2 (IC50 of 630 nM). Additionally, Indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor…
-
Spectinomycin Sulfate
MP BiomedicalsSpectinomycin sulfate is an antibiotic which binds to the 30S subunit to cause misreading. Spectinomycin sulfate is a broad spectrum antibiotic that inhibits protein synthesis (elongation) by binding to the bacterial 30S ribosomal subunit and interfering with peptidyl tRNA translocation.
-
Fluconazole
MP BiomedicalsFluconazole is a subclass of the synthetic triazole antifungal agents. A highly selective inhibitor of fungal cytochrome P-450 sterol C-14 a-demethylation. Fluconazole is a potent inhibitor of CYP2C9. Fluconazole interferes with fungal ergosterol synthesis and downregulates the metallothionein gene.
-
Chlorhexidine Digluconate Solution
MP BiomedicalsChlorhexidine digluconate, a bis(biguanide) family cationic broad spectrum antibiotic is an antiseptic and disinfectant agent. It is effective against a wide range of bacteria, some fungi and some viruses, and an agent for the prevention of gingivitis. Chlorhexidine digluconate solution inhibits…
-
Penicillin G Potassium Salt
MP BiomedicalsPenicillin G is a narrow spectrum antibiotic. Active against gram-positive and gram-negative aerobic and anaerobic bacteria Inhibits cell wall synthesis Stable against hydrolysis by β-lactamases, such as penicillinases and cephalosporinases The drug of choice for Streptococcus…
-
Actinonin
MP BiomedicalsProduct Description Antibiotic. Aminopeptidase M, N and leucine and alanine aminopeptidase inhibitor. Potent peptide deformylase (PDF) inhibitor. Inhibits MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-12 and MMP-13, but not MMP-14. Anticancer compound. Antiproliferative. Shows antitumor…
-
Penicillin G Potassium Salt
MP BiomedicalsPenicillin G potassium Salt is a salt of Penicillin G. Penicillin G is a hydrophobic, β-lactam antibiotic produced by Penicillium spp. Penicillin G is also known as benzylpenicillin and contains a 6’ phenylacetyl side chain. In acid aqueous solutions, Penicillin is reported to decompose…
-
Chloroquine Diphosphate Salt
MP BiomedicalsChloroquine Diphosphate salt is a member of the quinolone family and a lysosomotropic agent (accumulate inside the acidic parts of the cell). This accumulation leads to inhibition of lysosomal enzymes that require an acidic pH, and prevents fusion of endosomes and lysosomes. Chloroquine…
-
Gentamicin Sulfate
MP BiomedicalsGentamicin is an aminoglycoside antibiotic complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is a mixture of 3 major components designated as C1, C1a, and C2. Gentamicin is used as the sulfate salt. Each component consists of five basic nitrogens and requires five…
-
Tamoxifen
MP BiomedicalsTamoxifen is a Protein Kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in…
-
Valinomycin
MP BiomedicalsA metabolite with a broad antibiotic spectrum. Inhibitor of mitochonclrial action. K+-selective ionophoric cyclodepsipeptide; potassium ionophore which uncouples oxidative phosphorylation, induces apoptosis in murine thymocytes, inhibits NGF-induced neuronal differentiation and antagonizes…
-
Puromycin Dihydrochloride
MP BiomedicalsPuromycin is an antibiotic of unique structure and biological activity. It is produced by fermentation using Streptomyces albo-niger. There are four aspects of puromycin's biological activity that are 1) antitumor effect; 2) nephrotoxic action; 3) inhibition of purine and/or protein synthesis…
-
Tamoxifen Citrate Salt
MP BiomedicalsProtein Kinase C inhibitor. Tamoxifen Citrate Salt is a nonsteroidal triphenylethylene derivative. Tamoxifen and its metabolite 4-hydroxytamoxifen are mixed estrogen agonists/antagonists. Tamoxifen has been shown to protect bone from estrogen-deficiency bone loss and lower plasma cholesterol in…
-
Pyrimethamine
MP BiomedicalsPyrimethamine is a diamino-pyrimidine and folic acid antagonist. Pyrimethamine is a medication used for protozoal infections. It is commonly used as an antimalarial drug, and is also used (combined with sulfadiazine) in the treatment of Toxoplasma gondii infections in immunocompromised patients,…
-
Nalidixic Acid Sodium Salt
MP BiomedicalsNalidixic acid sodium salt is an antibacterial agent (synthetic quinolone antibiotic), which is inhibitor of bacterial DNA polymerase (DNA gyrase) & avian myeloblastoma virus reverse transcriptase. Inhibits nucleic acid and protein synthesis in Saccharomyces cerevisiae. Typically used at a…
-
Ampicillin
MP BiomedicalsAmpicillin is a semi-synthetic derivative of penicillin, active as a broad-spectrum antibiotic. It is inactivated by beta-lactamases and for this reason a beta-lactamase inhibitor should be considered when using ampicillin. Against gram-positive bacteria, ampicillin has a similar mode of action as…
-
Gentamicin Sulfate Reagent Solution
MP BiomedicalsGentamicin Sulfate Reagent Solution is recommended for use in cell culture applications at 5 ml/L and used as a selection agent (gentamicin-resistance gene) in molecular biology applications. Gentamicin is an aminoglycoside antibiotic complex produced by fermentation of Micromonospora purpurea…
-
G418 Disulfate, Phytopure™
MP BiomedicalsG418 is an aminoglycoside related to Gentamicin and is toxic to bacteria, yeast, higher plants, mammalian cells, protozoans and helminths. It blocks polypeptide synthesis in both prokaryotic and eukaryotic cells and is useful for selection of genetically engineered eukarytoic cells in culture.
-
Penicillin-Streptomycin
MP BiomedicalsSuitability: Suitable for cell culture Key Applications: Cell culture media supplement Product Type: Biochemicals Chemical Class: Antibiotics
-
Kanamycin Monosulfate
MP BiomedicalsKanamycin sulfate is an antimicrobial agent effective against Gram-negative and Gram-positive bacteria and mycoplasma. It binds to the 70S ribosomal subunit, inhibits translocation, and elicits miscoding. Cross-resistance occurs between kanamycin and neomycin, framycetin, and paromomycin, and…
-
Amoxicillin
MP BiomedicalsAmoxicillin is an antibacterial agent against gram-positive and gram-negative bacteria. Amoxicillin is a moderate-spectrum, β-lactam antibiotic. Amoxicillin is one of the most common antibiotics prescribed for children. It is used to study the oxygen dependent antimicrobial systems of…
-
Ofloxacin
MP BiomedicalsOfloxacin is a synthetic fluoroquinolone with broad-spectrum antibacterial activity. It is a nalidixic acid analog. Ofloxacin is used to study pneumococcal cell wall-degrading virulence factors. Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, which haults DNA replication and…
-
Ampicillin Trihydrate
MP BiomedicalsAmpicillin is a semi-synthetic derivative of penicillin, active as a broad-spectrum antibiotic. It is inactivated by beta-lactamases and for this reason a beta-lactamase inhibitor should be considered when using ampicillin. Against gram-positive bacteria, ampicillin has a similar mode of action as…
-
Blasticidin S Hydrochloride, Phytopure™, 250 mg
MP BiomedicalsBroad spectrum nucleoside antibiotic. Inhibits protein synthesis in prokaryotic and eukaryotic organisms. Suitable for selection of cells carrying plasmids conferring blasticidin resistance. Blasticidin S inhibits hydrolysis of peptidyl-tRNA induced by release factors. It enhances the binding of…
-
Amikacin
MP BiomedicalsAmikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections. Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth. Amikacin must be given by the…
-
Actinomycin D from Streptomyces parvalus
MP BiomedicalsActinomycin D is a polypeptide antibiotic first described by Waksman. It is bacteriostatic in nature, especially towards gram negative bacteria, and also has anti-tumor activity. Actinomycin D has a wide-ranging applications ranging from a selection agent in cell culture, use in studies of…
-
Chlortetracycline Hydrochloride
MP BiomedicalsChlortetracycline hydrochloride has antimicrobial action similar to tetracycline hydrochloride, but it is somewhat less active against many Gram-negative organisms. It was first isolated from the culture of Streptomyces aureofacien. Cell-permeable fluorescent probe for Ca2+ for measuring calcium…
-
Rapamycin
MP BiomedicalsRapamycin is a member of the macrolide immunosuppressant family and a FRAP inhibitor. Rapamycin is unique in its ability to inhibit lymphokine induced cell proliferation at the G1 and S phase as well as an irreversible cellular arrest at the G1 phase in S. cerevisiae cells. It also exhibits…
