Phosphatidylserine is a phospholipid component, usually present on the cytosolic side of cell membranes by an enzyme called flippase. When a cell undergoes apoptosis, phosphatidylserine is no longer restricted to the cytosolic part of the membrane, but becomes exposed on the surface of the cell. …

Oleoyl Coenzyme A Dipotassium Salt

Coenzyme A is an essential cofactor in enzymatic acetyl transfer reactions. Facilitates removal of lipid peroxides by increasing mobilization of fatty acids Promote repair of plasma membranes by activating phospholipid synthesis The principal biologically active forms of pantothenic…

Poly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding. A compromise between the easier to use lower molecular weight products…

AEBSF hydrochloride is a covalent binding serine protease inhibitor, belongs to the family of irreversible sulfonyl fluoride inhibitors that block trypsin and chymotrypsin-type enzymes. Similar in structure to the commonly used inhibitor PMSF, AEBSF offers better solubility in water, lower…

Retinoic acid (RA) is a vitamin A-derived, non-peptidic, small lipophilic molecule that mediates the functions of vitamin A required for growth and development. It affects gene transcription and modulates a wide variety of biological processes like Cell Proliferation, Differentiation, including…

Pure Canavalia ensiformis lectin (Con A) from Jackbean. Isolated by affinity chromatography on cross-linked dextran. Con A exists as a dimer below pH 5.0 and and at pH >7 it exists as a tetramer. Con-A is not a glycoprotein. The monomeric molecular weight of Con-A is 25,500. Con-A does not…

Papain is a sulfhydryl protease from Carica papaya latex. Cleaves peptide bonds of basic amino acids, leucine, or glycine Hydrolyzes esters and amides One unit will hydrolyze 1.0 µmole of N-alpha-benzoyl-L-arginine ethyl ester (BAEE) per minute at 25°C and pH 6.2 Papain…

Poly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein. It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When…

The total protein is determined using the Biuret procedure, with bovine albumin as the standard. Each vial is overfilled by approximately 10 percent so that a minimum of 50 mg of mouse albumin Fraction V is obtained upon reconstitution. Mouse albumin Fraction V is purified from pooled mouse…

Poly-L-lysine is a positively charged amino acid polymer. Poly-lysine binds to DNA, red cell membrane and any negatively charged protein. It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell…

β-NADP is a coenzyme necessary for the alcoholic fermentation of glucose and the oxidative dehydrogenation of other substances. It occurs widely in living tissue, especially in the liver. Nicotinic acid can be converted to nicotinamide in the body and, in this form, is found as a component of…

Heparin is a polymer classified as a mucopolysaccharide or a glycosoaminoglycan. It is biosynthesized and stored in mast cells of various mammalian tissues, particularly liver, lung and mucosa. It is made up of repeated disaccharide units consisting of 1,4-linked L-iduronic acid and D-glucosamine.…

Potent phenolic antioxidant found in grapes and red wine. Eicosanoid synthesis and platelet aggregation inhibitor. Estrogen receptor agonist. Chemopreventive. Specific inhibitor of cyclooxygenase-1 (COX-1). Anti-inflammatory. Ribonucleotide reductase and DNA synthesis. Arrests cell cycle at S/G2…

Fluconazole is a subclass of the synthetic triazole antifungal agents. A highly selective inhibitor of fungal cytochrome P-450 sterol C-14 a-demethylation. Fluconazole is a potent inhibitor of CYP2C9. Fluconazole interferes with fungal ergosterol synthesis and downregulates the metallothionein gene.

Poly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein. Molecular weight has been determined by Viscosity as well as by HPLC. It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction…

Elastase is an enzyme from the class of proteases (peptidases) that break down proteins. It hydrolyzes peptide bonds, especially those adjacent to neutral amino acids. Hydrolyses elastin Digests hemoglobin, casein, and fibrin One unit will solublize 1 mg of elastin in 20 minutes at…

Ribonuclease belongs to pancreatic ribonuclease family. RNase A is an endoribonuclease that attacks at the 3¢ phosphate of a pyrimidine nucleotide. The sequence of pG-pG-pC-pA-pG will be cleaved to give pG-pG-pCp and A-pG. Ribonuclease A is used to remove RNA from DNA plasmid preparations…

α-Amylase isolated from porcine pancreas is a glycoprotein. It is a single polypeptide chain of ~475 residues containing two SH groups and four disulfide bridges and a tightly bound Ca2+ necessary for stability. Chloride ions are necessary for activity and stability. α-Amylase is…

All blood products should be treated as potentially infectious. Source material from which this product was derived was found negative when tested in accordance with current FDA required tests. No known test methods can offer assurance that products derived from human blood will not transmit…

Gentamicin is an aminoglycoside antibiotic complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is a mixture of 3 major components designated as C1, C1a, and C2. Gentamicin is used as the sulfate salt. Each component consists of five basic nitrogens and requires five…

Glyceryl Monooleate is a surfactant that releases free glycerol and oleic acid upon hydrolysis. Glyceryl Monooleate has been used in liquid crystal studies and research shows that in the presence of monoolein, the penetration of the drug cisplatin is doubled. Monoolein (1-Oleoyl-rac-glycerol) is…

Erlose is used in studies on dietary preference and utilization of trisose sugars from aphid honeydew by various insects, such as honey bees and ants. Erlose may be used as a reference compound in assays that analyze the sugars of foods such as royal jelly and honey.

Cell-permeable, reversible, substrate competitive tyrosine kinase inhibitor (including EGFR phosphorylation), implicated in almost all cell growth and proliferation signal cascades. Inhibitor of mammalian DNA topoisomerase II. Anticancer agent, inducing cell cycle arrest and apoptosis.…

Potent phenolic antioxidant found in grapes and red wine. Eicosanoid synthesis and platelet aggregation inhibitor. Estrogen receptor agonist. Chemopreventive. Specific inhibitor of cyclooxygenase-1 (COX-1). Anti-inflammatory. Ribonucleotide reductase and DNA synthesis. Arrests cell cycle at S/G2…

An antineoplastic of Rhodomycin group; Antibiotic; Inhibitor of enzymes and metabolic pathways. A potent anticancer agent that has been shown to be a strong inhibitor of DNA and RNA synthesis. Daunorubicin hydrochloride is used in photostability , antileukemic, and drug metabolism studies. …

The total protein is determined using the Biuret procedure, with bovine albumin as the standard. Each vial is overfilled by approximately 10 percent so that a minimum of 50 mg of rabbit IgG is obtained upon reconstitution. Rabbit IgG is purified from pooled rabbit serum using multi-step…

Hypolipemic cell permeable and irreversible pancreatic, gastric and carboxylester lipase inhibitor. Anti-obesity and antihypercholesterolemic compound. Antitumor compound by inhibition of the thioesterase domain of fatty acid synthase (FASN). Anti-proliferative. Causes cell cycle arrest at G1…

Actinomycin D is a polypeptide antibiotic first described by Waksman. It is bacteriostatic in nature, especially towards gram negative bacteria, and also has anti-tumor activity. Actinomycin D has a wide-ranging applications ranging from a selection agent in cell culture, use in studies of…

Important Notice: This product belongs to MP Biomedicals Rare Chemical library. Most Rare Chemical products are available for immediate delivery and sold "As Is". MP Biomedicals does not collect analytical data for those products. All sales are final. However, analytical test may be…

Intrinsic factor is a glucoprotein extracted from the pylorus part of the gastric mucous membrane. Its presence is considered necessary for the absorption of Vitamin B-12. Intrinsic Factor is used in the treatment not only of classical pernicious anaemia, but also in the treatment of other…

Arginine-rich subgroup. Commonly used for chromosome-reconstitution studies. Suitable substrate for protein kinase C.