Etoposide is an important chemotherapeutic agent that is used to treat a wide spectrum of human cancers. It also belongs to the drug type plant alkaloid. The primary cytotoxic target for etoposide is topoisomerase II. This ubiquitous enzyme regulates DNA under- and overwinding, and removes knots…

β-Sitosterol is a common plant steroid that possesses anticholesteremic properties. β-Sitosterol has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways.

Natural tomato lycopene is a mixture of isomers, primarily (all-E), but also some (5-Z) and two lesser and unidentified cis isomers, all of which are difficult to resolve by LC. Lycopene is an open chain unsaturated carotenoid that gives tomatoes, guava, rose hip, watermelon and pink grapefruit its…

Mineral oil is used as an overlay covering microdrops of culture medium in petri dishes, during the culture of oocytes and embryos in IVF and related procedures. It also has its applications in food processing, cosmetics and pharmaceuticals. A mineral oil is any of various colorless, odorless,…

Vitamin D3 is the naturally occuring form of vitamin D3. Vitamin D3 mediates intestinal calcium absorption, bone metabolism, and probably muscle activity. It acts as a hormone precursor since it requires two stages of metabolism: first to 25-hydroxycholecalciferol; then to 1 ,…

Zeolite, a microporous, aluminosilicate mineral, is used as a molecular sieve and as an adsorbent of a wide variety of cations, such as Na+, K+, Ca2+, Mg2+ and others. Hydrated alkali-aluminum silicate. Zeolites occur naturally in sedimentary and volcanic rocks, altered basalts, ores, clay…

Trichloroacetic acid is an acetic acid analogue commonly used to precipitate proteins, DNA and RNA. In the presence of SDS Trichloroacetic acid will precipitate proteins which can then be quantified by the Lowry method. The compound has also found uses as a decalcifier and fixative in microscopy,…

Acetic anhydride is a reagent that is used in the manufacturing of acetyl compounds and cellulose acetates. It is also utilized as a solvent in the examination of wool fat, glycerol, fatty and volatile oils, and resins. In the synthesis of organic compounds, acetic anhydride is used in various…

Chloroplatinic acid hexahydrate is an analytical reagent. Chloroplatinic acid is used in potassium determination, purification of platinum and in catalysis.

2-Hydroxypropyl-beta-Cyclodextrin are non-toxic solubilizers. The solubility of drugs increases linearly with the concentration of 2-Hydroxypropyl-b-cyclodextrin in aqueous buffer. The formation of drug/cyclodextrin complexes is a rapidly reversible reaction and complexes exist both in solution and…

Heparin is a polymer classified as a mucopolysaccharide or a glycosoaminoglycan. It is biosynthesized and stored in mast cells of various mammalian tissues, particularly liver, lung and mucosa. It is made up of repeated disaccharide units consisting of 1,4-linked L-iduronic acid and D-glucosamine.…

The product contains vitamin A acetate (approximately 21%) finely dispersed in a starch-coated matrix of gelatin (approximately 60%), sucrose (approximately 14%) and corn starch (approximately 5%). BHT and BHA are added as antioxidants. Vitamin A Acetate induces cell differentiation and inhibits…

Retinoic acid (RA) is a vitamin A-derived, non-peptidic, small lipophilic molecule that mediates the functions of vitamin A required for growth and development. It affects gene transcription and modulates a wide variety of biological processes like Cell Proliferation, Differentiation, including…

The molecule is a dialdehyde, consisting of two formyl (CHO) groups attached to adjacent carbon centres on a benzene ring. o-Phthalaldehyde is used for precolumn derivatization of amino acids for HPLC separation and for flow cytometric measurements of protein thiol groups. Used for fluorometric…

Glutaraldehyde is a bifunctional protein cross-linking reagent, reacting with NH2 groups to form Schiff's bases. Sporicidal agent. Glutaraldehyde reacts through cross-linking to impart water resistance to protein and polyhydroxy compounds. It is also a reducing agent for photochemicals. In…

Cetylpyridinium chloride is used is in some types of mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. It is an antiseptic that kills bacteria and other microorganisms. It has been shown to be effective in preventing dental plaque and reducing gingivitis.

Paraformaldehyde (PFA) is the smallest polyoxymethylene. It is polymerization product of formaldehyde. Paraformaldehyde has been used in the past for disinfecting sickrooms, clothing, linen and sickroom utensils. It has been used as a fumigant and in manufacturing synthetic resins & as a…

Dexamethasone is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S…

Beta-glucuronidases are members of the glycosidase family of enzymes that catalyze the breakdown of complex carbohydrates. Human β-glucuronidase is a type of glucuronidase that catalyzes hydrolysis of β-D-glucuronic acid residues from the non-reducing end of mucopolysaccharides, such as…

Hydrochloric acid is used as a laboratory reagent, for pickling of steel, in production of organic and inorganic compounds, for pH control and neutralization, used in the regeneration of ion exchange resins, in the production of food, food ingredients, and food additives. Chlorine source for safer,…

Diatomaceous Earth, Acid-washed is an inert material. Diatomaceous earth acid-washed is used as a filtration aid. It is suitable for most routine filtrations.

Hexamethylenetetramine is a tetraamine compound with a structure analogous to adamantane. Hexamethylenetetramine is used for amino acid preparation. It is also used in synthesis as a formylation agent and is employed in preparing specialized materials. It is also used as a precipitating agent. …

Lidocaine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Lidocaine is also an anasthetic and class Ib antiarrhythmic agent. This compund is known to block voltage-gated sodium channels in the inactivated state. Lidocaine is a second-generation…

p-Dimethylaminobenzaldehyde is used as a reagent for the determination of amino acids and peptides, amines, indoles, hydrazines and hydrogen peroxides as it forms colored condensation products (Schiff bases) with pyrroles and primary amines; spray reagent for tryptophan; For the determination of…

Ferric chloride is a moderately strong Lewis acid. Ferric Chloride is used in photoengraving, photography, the manufacture of pigments and ink, the chlorination of silver and copper ores, and as a mordant in dyeing and printing textiles. It is also utilized in the synthesis of organic compounds.…

N,N,N',N'-Tetramethylethylenediamin is a tertiary amine base. N,N,N',N'-Tetramethylethylenediamine is used to catalyze the formation of free radicals from ammonium persulfate or riboflavin. The free radicals will cause acrylamide and bis-acrylamide to polymerize to form a gel…

4-Aminoantipyrine is a reagent for determination of chlorinated phenols, phenylglycosidase, and glucose in the presence of phenol and peroxidase.

Vitamin B12 (cobalamin) refers to a group of chemically-related cobalt containing molecules involved in cell processes such as DNA synthesis, fatty acid synthesis, energy production and regulation. The physiologically active forms of vitamin B12 include methylcobalamin and adenosylcobalamin,…

Chrome Azurol S is used as a reagent for determination of fluoride.

Tween 80 is a polyethylene sorbitol ester, non ionic surfactant and an emulsifier derived from polyethoxylated sorbitan and oleic acid. Tween 80 has been widely used in biochemical applications including: solubilizing proteins, isolating nuclei from cells in culture, growing of tubercule…

Folic acid, also known as folate, is a B vitamin that can be found in a variety of fruits and vegetables. It can also be chemically synthesized. Folate, a watersoluble vitamin, helps the body form red blood cells and aids in the formation of genetic material within every body cell. Folic Acid is a…