Vitamin D3 is the naturally occuring form of vitamin D3. Vitamin D3 mediates intestinal calcium absorption, bone metabolism, and probably muscle activity. It acts as a hormone precursor since it requires two stages of metabolism: first to 25-hydroxycholecalciferol; then to 1 , 25-dihydroxycholecalciferol.
Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.
Product Type: Biochemicals
Chemical Class: Pharmaceuticals
Melting Point: 82 - 92°C
Extinction Coefficient (E1%): EmM(265nm) = 18.2 (Hexane or ethanol) (Lit.)
Presentation: White Powder
Solubility: Soluble in ethanol, acetone, ether, chloroform; insoluble in water. Practically insoluble in water: soluble in the usual organic solvents; slightly soluble in vegetable oils.
Storage & Handling: Store at +4°C, desiccate.