Folic acid, also known as folate, is a B vitamin that can be found in a variety of fruits and vegetables. It can also be chemically synthesized. Folate, a watersoluble vitamin, helps the body form red blood cells and aids in the formation of genetic material within every body cell. Folic Acid is a hematopoietic vitamin present, free or combined with one or more additional molecules of L-(+)-glutamic acid, in liver, kidney, mushrooms, spinach, yeast, green leaves, and grasses.
A nutritional delivery form of folate. Folic acid and its derivatives are essential mediators of one-carbon metabolism within cells.
Grade: Cell Culture Reagent
Purity: ≥95%
Product Type: Biochemicals
Extinction Coefficient (E1%): EmM= 9.12, 25.1, 26.9 (0.1 M NaOH) (Lit.)
Optical Rotation: +23° ( 0.5 %, 0.1 M NaOH, 25°C) (Lit.)
UV/Visible Absorbance: λ max: 256 ± 3nm (0.1N NaOH)
Presentation: Orange Powder
Format: Powder
pH: A suspension of 1 g folic acid in 10 mL water has a pH of 4.0-4.8. Aqueous solutions prepared with sodium bicarbonate have a pH between 6.5 and 6.8.
pKa: 8.26 (Lit.)
Detection Method: FTIR
Loss on Drying: ≤8.5%
Residue on ignition: ≤0.3%
Solubility: Very slightly soluble in cold water (0.0016 mg/mL at 25°C), soluble to about 1% in boiling water. Slightly soluble in methanol, appreciably less soluble in ethanol and butanol. Insoluble in acetone, chloroform, ether, benzene. Relatively soluble in acetic acid, phenol, pyridine, solutions of alkali hydroxides (1 M NaOH - 50 mg/mL) and carbonates. Soluble in hot dilute HCl and H2SO4.
Storage & Handling: Store at Room Temperature (15-30°C). Protect from light.