Antigen: purified human recombinant PCSK9 Host: mouse, clone 15A6 Isotype: IgG1 Cross Reactivity: (+) human recombinant PCSK9 Application(s): PCSK9 ligand blotting (nondenaturing conditions) and WB PCSK9 is a member of the subtilisin serine protease family with an important role in…

Antigen: recombinant adenovirus expressing full-length mouse CD36 Host: CD36 null mouse, clone JC63.1 Cross Reactivity: (+) human, mouse, and rat CD36 Application(s): FC, functional blocking, and ICC Functioning as a receptor for oxidized LDL, CD36 is a type-B scavenger receptor that is…

Immunogen: Synthetic peptide from the C-terminal region of human protein COX-2 Host: Mouse, clone CX229 Isotype: IgG1 Species Reactivity: (+) Human, ovine, and monkey COX-2; (−) Mouse, rat, and rabbit COX-2 and COX-1 (all species) Cross Reactivity: (-) COX-1 (all species) …

Antigen: human COX-2 amino acids 580-599 Host: mouse, clone CX229 Cross-Reactivity: (+) human and ovine COX-2; (−) mouse, rat, and rabbit COX-2 and COX-1 (all species) Application(s): (+) FC and ICC; (−) IHC and WB Isotype: IgG1 This product is derived by labeling the…

Antigen: human CD45 Host: mouse, clone BRA-55 Cross Reactivity: (+) human CD45 Application(s): FC, ICC, IHC (formalin-fixed paraffin-embedded tissue and frozen sections), and WB

Antigen: bovine lung PGIS Host: mouse, clone isn-1 Cross Reactivity: (+) bovine, mouse, rat, ovine, guinea pig, and rabbit PGIS Isotype: IgG1 Application(s): IHC and IP; WB not recommended PGIS catalyzes the conversion of PGH2 to PGI2 (prostacyclin).

Antigen: recombinant full-length human caspase-3 Host: mouse, clone 31A1067 Isotype: IgG1κ Cross Reactivity: (+) human, mouse, and rat caspase-3 Application(s): IHC (frozen and paraffin-embedded sections) and WB Caspase-3 cleaves the death substrate PARP to a specific 85 kDa…

Antigen: synthetic peptide containing phosphorylated serine residues corresponding to human IκBα amino acids 32 and 36 Host: mouse, clone 39A1413 Isotype: IgG1κ Cross Reactivity: (+) bovine, canine, human, mouse, porcine, and rat IκBα …

Antigen: hamster brain SAF Host: mouse, clone SAF 61 Isotype: IgG Application(s): EIA and FC

Antigen: recombinant full-length human caspase-3 Host: mouse, clone 31A893 Cross Reactivity: (+) human caspase-3 Application(s): WB Caspase-3 cleaves the death substrate PARP to a specific 85 kDa form observed during apoptosis and is inhibitable by the CrmA protein. Other caspase-3…

Antigen: human caspase-8 amino acids PVETDSEEQP Host: mouse, clone 90A992 Isotype: IgG1 Cross Reactivity: (+) human, chimpanzee, and Rhesus monkey caspase-8 Application(s): FC, IHC (paraffin-embedded tissue), and WB Caspase-8 forms a direct link between the activation of CD95 and the…

Antigen: synthetic peptide corresponding to amino acids 637-650 of human DNMT1 Host: mouse, clone 60B1220.1 Isotype: IgG1κ Cross Reactivity: (+) human, mouse, and zebrafish DNMT1 Application(s): ChIP, IHC (paraffin-embedded sections), IP, and WB DNMT1 is constitutively…

Antigen: recombinant human H-PGD synthase Host: mouse, clone 2A5 Cross-reactivity: (+) human and mouse H-PGD synthase Applications: IHC and WB Isotype: IgG2bκ

Epitope: Binds to N-terminal amino acids 16-25 of wild-type and mutant p53 Host: Mouse, clone BP53-12 Isotype: IgG2a Species Reactivity: (+) Human p53 Application(s): FC, ICC, IHC (paraffin-embedded sections), and WB Cellular p53, often called the 'guardian of the genome,' is…

Antigen: recombinant human PrP Host: mouse, clone 12F10 Isotype: IgG Application(s): IHC and WB

Host: mouse, clone RIV7 Cross Reactivity: (+) human CD4 Application(s): (+) FC, ICC, and IHC (frozen sections); (−) IHC (paraffin-embedded tissue) and WB Isotype: IgG2a

Antigen: human recombinant prion protein Host: mouse, clone 11C6 Isotype: IgG Application(s): EIA, FC, and WB

Antigen: synthetic peptide containing amino acids near the 214/215 cleavage site of human PARP Isotype: IgG2bκ Host: mouse Cross Reactivity: (+) human PARP Application(s): FC (intracellular) and WB PARP is a 116 kDa nuclear chromatin-associated enzyme that is cleaved during…

Antigen: human recombinant sPLA2 (type IIA) Host: mouse Cross-Reactivity: (+) human sPLA2 (type IIA); (−) bee venom sPLA2 (type III) and human sPLA2 (type V) Application(s): WB, IHC and IP; other applications not tested Isotype: IgG1 Clone designation: SCACC353

Host: mouse, clone CRIS1 Cross-Reactivity: (+) human CD5 Application(s): (+) FC, IF, and IHC (frozen sections); (−) IHC (paraffin-embedded tissue) and WB

Antigen: hamster brain SAF Host: mouse Isotype: IgG2b Cross Reactivity (PrPc): (+) hamster, mouse, bovine, ovine, and human PrP Application(s): WB

Host: rat Cross Reactivity: (+) mouse podoplanin Application(s): FC and WB

Antigen: full-length recombinant human HMGB1 Host: mouse, clone IMG19N12A1 Isotype: IgG1k Cross Reactivity: (+) human and mouse HMGB1 Application: WB HMGB1 is a necessary and sufficient mediator of inflammation during sterile and infection-associated responses. HMGB1 also act as DNA…

Antigen: human Akt1 containing phospho-serine473 Host: mouse, clone 104A282 Isotype: IgG2κ Cross Reactivity: (+) human and mouse Akt1 Application(s): IP and WB Akt/PKB is a serine/threonine kinase that mediates cell survival and is thought to be a critical factor in the genesis…

Antigen: a portion of amino acids 150-200 of human NF-κB (p50) Host: mouse, clone 2J10D7 Isotype: IgG1κ Cross-Reactivity: (+) human NF-κB (p50) Application(s): IHC and WB NF-κB1 (p50) is a 50 kDa functional sub-unit of NF-κB that forms…

Antigen: synthetic peptide corresponding to human NF-κB (p65) amino acids 526-539 Host: mouse, clone 112A1021 Isotype: IgG1κ Cross-Reactivity: (+) human, mouse, and rat NF-κB (p65) Application(s): ELISA The active nuclear form of the NF-κB…

Immunogen: recombinant adenovirus expressing full-length mouse CD364 Host: CD36 null mouse, clone JC63.1 Species Reactivity: (+) human, mouse, and rat CD36 Application(s): FC and IF Functioning as a receptor for oxidized LDL, CD36 is a type-B scavenger receptor that is necessary for the…

Antigen: human full length p38 MAPK Host: mouse, clone 9F12 Cross Reactivity: (+) human, mouse, and rat p38 MAPK Application(s): FC, ICC, and WB p38 MAPK is a member of the serine-threonine MAPK family that triggers many cellular processes including cell cycle, development, and apoptosis.

Immunoge: Peptide from the N-terminal region of mouse PEPCK Host: Rabbit Species Reactivity: (+) mouse and rat PEPCK protein Application(s): WB PEPCK catalyzes the conversion of oxaloacetate to phosphoenolpyruvate, the first committed step in gluconeogenesis. Both non-insulin-dependent…

Antigen: N-terminal 80 amino acids of human Trx1 Host: mouse, clone 7D11 Isotype: IgG1 Application(s): ELISA, IF, IP, and WB

Antigen: mouse Trx1 Host: rabbit Application(s): WB Cross Reactivity: (+) rat and mouse cytosolic Trx1

Antigen: human NF-κB (p65) amino acids 526-539 Host: mouse, clone 112A1021 Isotype: IgG1κ Cross-Reactivity: (+) human, mouse, and rat NF-κB (p65); expected to react with bovine, gorilla, monkey, and porcine NF-kB (p65) Application(s): FC, IHC, and WB The…