Antigen: recombinant human Nod2 residues 28-301 Host: rabbit Application(s): WB and IP; may not detect basal levels of Nod2 in monocytes

Antigen: mouse/rat COX-2 amino acids 570-598 Host: rabbit Cross-Reactivity: (+) human, guinea pig, monkey, mouse, ovine, rabbit, and rat COX-2; (−) COX-1 (all species) Application(s): ICC, IHC, and WB

Immunogen: peptide from an internal region of ovine COX-1 Host: rabbit Cross reactivity: (-) ovine, human, and mouse COX-2 Species reactivity: (+) ovine seminal vesicle, human, bovine endothelial, and porcine COX-1 Applications: WB, ICC, IHC

Antigen: rat soluble guanylate cyclase β1 subunit (soluble) amino acids 188-207 Host: rabbit Cross Reactivity: (+) human, bovine, and rat soluble guanylate cyclase β1 subunit; (−) α1 subunit Application(s): IHC and WB Soluble guanylate cyclase is a heterodimeric…

Antigen: purified enzyme from mouse macrophages (RAW 264.7 cells) Host: rabbit Cross Reactivity: (+) iNOS from most mammalian species and nNOS (~5%); (−) eNOS Application(s): ICC, IP, and WB NOS catalyzes the biosynthesis of nitric oxide from L-arginine. iNOS is a soluble enzyme…

Immunogen: synthetic peptide from the N-terminal region of human H-PGDS Host: rabbit Species Reactivity: (+) human, baboon, mouse, and rat H-PGDS Application(s): WB

Antigen: human 11β-HSD1 amino acids 78-92 (CLELGAASAHYIAGT) Host: rabbit Cross-reactivity: (+) human, mouse, and rat 11β-HSD1 Applications: IHC (formalin-fixed paraffin-embedded tissue) and WB 11β-HSD1 catalyzes the conversion of inactive cortisone to active cortisol in…

Antigen: human COX-2 amino acids 578-596 Host: goat Cross-Reactivity: (+) human, ovine, mouse, rat COX-2; (−) COX-1 (all species) Application(s): WB, ICC, and IHC (formalin-fixed paraffin-embedded sections) Expression of COX-2, the inducible form of COX, is regulated by growth…

Antigen: purified human recombinant PCSK9 Host: mouse, clone 15A6 Isotype: IgG1 Cross Reactivity: (+) human recombinant PCSK9 Application(s): PCSK9 ligand blotting (nondenaturing conditions) and WB PCSK9 is a member of the subtilisin serine protease family with an important role in…

Antigen: human CD45 Host: mouse, clone BRA-55 Cross Reactivity: (+) human CD45 Application(s): FC, ICC, IHC (formalin-fixed paraffin-embedded tissue and frozen sections), and WB

Immunogen: peptide from the C-terminal region of human BLT2 Host: rabbit Species Reactivity: (+) human and mouse BLT2 receptor Application(s): WB

Immunogen: synthetic peptide from the N-terminal region of human protein Host: rabbit Cross Reactivity: (+) human, mouse, rat, porcine, and bovine β-catenin Application(s): IHC and WB β-Catenin is a multifunctional protein known to be part of the Wnt pathway, playing essential…

Antigen: synthetic peptide corresponding to human IRAK-1 amino acids 700-712 Host: rabbit Cross Reactivity: (+) human and mouse IRAK-1; (−) IRAK-2 Application(s): IP and WB IRAK-1 is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a…

Antigen: human COX-2 amino acids 580-599 Host: mouse, clone CX229 Cross-Reactivity: (+) human and ovine COX-2; (−) mouse, rat, and rabbit COX-2 and COX-1 (all species) Application(s): (+) FC and ICC; (−) IHC and WB Isotype: IgG1 This product is derived by labeling the…

Antigen: recombinant adenovirus expressing full-length mouse CD36 Host: CD36 null mouse, clone JC63.1 Cross Reactivity: (+) human, mouse, and rat CD36 Application(s): FC, functional blocking, and ICC Functioning as a receptor for oxidized LDL, CD36 is a type-B scavenger receptor that is…

Antigen: human DcR2 precursor amino acids 249-263 Host: rabbit Cross Reactivity: (+) human DcR2 Application(s): WB DcR2 has an extracellular TRAIL-binding domain but lacks an intracellular death domain and does not induce apoptosis. Like DR4 and DR5, DcR2 transcript is widely expressed…

Antigen: purified ovine COX-1 Host: rabbit Cross-Reactivity: reacts with both COX-1 and -2; affinity for COX-1>COX-2 Application(s): WB and IHC

Antigen: Peptide from the C-terminal region of human dopamine β-hydroxylase (DBH) Host: sheep Cross Reactivity: (+) Human, mouse, and non-human primate tissue DBH Application: WB

Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Thr34 of rat DARPP-32 Host: rabbit Cross Reactivity: (+) rat DARPP-32 Application(s): WB DARPP-32 is a dopamine and cAMP-regulated phosphoprotein that plays a critical role in the regulation of dopaminergic…

Peptide Sequence: soluble rat guanylate cyclase β1 subunit, amino acids 188-207 (EDFYEDLDRFEENGTQDSR; last D=E in human and bovine) To be used in conjunction with Cayman’s guanylate cyclase β1 subunit (soluble) polyclonal antibody (Catalog No. 160897) to block protein-antibody…

Antigen: bovine lung PGIS Host: mouse, clone isn-1 Cross Reactivity: (+) bovine, mouse, rat, ovine, guinea pig, and rabbit PGIS Isotype: IgG1 Application(s): IHC and IP; WB not recommended PGIS catalyzes the conversion of PGH2 to PGI2 (prostacyclin).

Antigen: phosphopeptide corresponding to amino acid residues surrounding phospho-Ser301 of rat Raf-1 Host: rabbit Cross Reactivity: (+) rat Raf-1; expected to react with bovine, canine, chicken, human, mouse, non-human primate, and Xenopus Raf-1 Application(s): WB Studies have shown…

Immunogen: peptide affinity-purified IgG Host: rabbit Species Reactivity: (+) human, bovine, and mouse sGC a1 subunit Application(s): WB Soluble guanylate cyclase is a heterodimeric enzyme, composed of α and β subunits, that synthesizes cGMP from GTP. The enzyme is activated…

Immunogen: Synthetic peptide from the C-terminal region of human protein COX-2 Host: Mouse, clone CX229 Isotype: IgG1 Species Reactivity: (+) Human, ovine, and monkey COX-2; (−) Mouse, rat, and rabbit COX-2 and COX-1 (all species) Cross Reactivity: (-) COX-1 (all species) …

Antigen: human endothelial lipase amino acids 19-32 Host: rabbit Cross Reactivity: (+) human, mouse, rat, porcine, and ovine endothelial lipase Application(s): IHC and WB EL is a major genetic determinant for the concentration, structure, and metabolism of HDL, which protects against atherosclerosis.

Antigen: human 11β-HSD2 amino acids 25-40 (RSDLRLGRPLLAALAL) Host: rabbit Cross Reactivity: (+) human, mouse, and rat 11β-HSD2 Application(s): WB 11β-HSD2 plays a critical role in normal physiology in the corticosteroid regulation of sodium homeostasis and the…

Antigen: phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser33,37 of human β-catenin Host: rabbit Cross-reactivity: (+) human β-catenin Application: WB β-Catenin is a central component of the cadherin cell adhesion complex and plays an…

Peptide Sequence: human 11β-HSD1 amino acids 78-92 (CLELGAASAHYLAGT) To be used in conjunction with Cayman’s 11β-HSD1 polyclonal antibody (Catalog No. 10004303) to block protein-antibody complex formation during immunochemical analysis of 11β-HSD1.

Antigen: Peptide from the N-terminal region of human dopamine β-hydroxylase (DBH) Host: sheep Cross Reactivity: (+) Human and non-human primate tissue DBH Application: WB

11-Hydroxysteroid dehydrogenase type 2 (11β-HSD2) plays a critical role in normal physiology in the corticosteroid regulation of sodium homeostasis and the pathophysiology of hypertension by converting active cortisol to inactive cortisone. Mutation in the gene encoding 11β-HSD2 results…

Antigen: human BLT1 receptor amino acids 331-352 (ALEPGPSESLTASSPLKLNELN) Host: rabbit Cross Reactivity: (+) human and bovine BLT1 receptor; (−) mouse BLT1 receptor Applications: CF, FC, IHC (formalin-fixed paraffin-embedded tissue), and WB The human BLT1 receptor is a GPCR that…

Immunogen: synthetic peptide from C-terminal region of human optineurin Host: rabbit Species-Reactivity: (+) human optineurin Application(s): WB