FUJIFILM

FUJIFILM

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  • Recombinant Human HB-EGF

    Heparin-binding EGF-like growth factor (HB-EGF) is a member of the epidermal growth factor (EGF) family and is expressed by monocytes and macrophages. HB-EGF is the predominant growth factor involved in epithelialization during wound healing. HB-EGF signals through the receptor tyrosine kinase ErbB2...

  • Recombinant Human FRACTALKINE / CX3CL1

    Fractalkine, also known as CX3CL1, is a cytokine protein containing a CX3C chemokine motif atop a mucin stalk. Fractalkine is produced by non-hemopoietic cells, including neurons and astrocytes. Soluble fractalkine functions as a chemoattractant for T cells and monocytes. Cell-membrane-bound...

  • Recombinant Human BCA-1 / CXCL13

    B cell-attracting chemokine 1 (BCA-1), also known as CXCL13, is expressed at high levels in lymphoid tissues, such as the spleen, lymph nodes, and Peyer’s patches. BCA-1 activates signaling through the receptor Burkitt lymphoma receptor 1 (BLR1) to chemoattract B cells.

  • Recombinant Mouse RANK Ligand

    Receptor activator of nuclear factor kappa-B Ligand (RANK Ligand) is a cell-bound marker related to the tumor necrosis factor (TNF) family of proteins. RANK Ligand plays a critical role in bone metabolism and osteoclast differentiation. T cell expression of RANK Ligand promotes dendritic cell...

  • PRIME-XV FreezIS DMSO-Free

    DMSO-free, protein-free, animal component-free, chemically defined cryopreservation solution Eliminate the risk of DMSO toxicity and maintain potency of human mesenchymal stem cells (MSCs), T cells, and hematopoietic stem cells (HSCs) throughout cryopreservation Comparable post-thaw cell viability...

  • Recombinant Human IL-1RA

    Interleukin-1 receptor antagonist (IL-1RA) binds the interleukin 1 receptor (IL-1R) to antagonize interleukin 1 alpha and beta signaling. IL-1RA is secreted by immune cells, epithelial cells, hepatocytes, and adipocytes to inhibit IL-1-induced inflammation. IL-1RA therapy is used to treat...

  • CTGrade GMP rh SCF

    SCF is a multipotent factor which affects cells of the myeloid, erythroid, mast, and lymphoid lineages. • Exists both as a membrane-bound and soluble form • Expressed by fibroblasts and endothelial cells promoting proliferation, migration, survival, and differentiation in hematopoietic progenitors,...

  • Recombinant Mouse IL-2

    Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes. IL-2 signals through the IL-2R receptor to induce activated T cell proliferation and promote T cell differentiation. IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells,...

  • Recombinant Mouse / Rat FGF-ACIDIC / FGF-1

    Acidic fibroblast growth factor (FGF-acidic), also known as FGF-1, is a potent inducer of DNA synthesis, cell proliferation, and has chemotactic activities. FGF-acidic regulates cardiogenesis through protein kinase C signaling. FGF-acidic also functions as an insulin sensitizer and mediates adipose...

  • Recombinant Mouse IL-17F

    Interleukin 17F (IL-17F), a member of the IL-17 cytokine family, is secreted by activated CD4+ T cells and monocytes. IL-17F binds the IL-17 receptor related molecule, IL17RC, to promote the production of the interleukin 6 (IL-6), interleukin 8 (IL-8), and granulocyte macrophage colony-stimulating...

  • Recombinant Mouse MCP-1 / CCL2

    Monocyte chemotactic protein 1 (MCP-1), also known as CCL2, is produced by injured or infected tissues. MCP-1 signals through the CCR2 and CCR4 G protein-coupled receptors to recruit memory T cells, monocytes, and dendritic cells to sites of inflammation.

  • CTGrade GMP rh IL-6

    IL-6 is an important pro-inflammatory and anti-inflammatory cytokine expressed by T cells, macrophages, and muscle cells. • Signals through a receptor complex containing two receptors, IL-6Ra and gp130 • Plays an important function in promoting fever and can serve to stimulate an immune response to...

  • Recombinant Mouse Follistatin

    Follistatin is an autocrine, activin-binding protein that is ubiquitously expressed with highest expression levels being in the ovary and skin. Follistatin negatively regulates the signaling of transforming growth factor beta (TGF-ß) family members, such as activin, bone morphogenetic proteins...

  • Recombinant Human / Mouse / Rat ACTIVIN-A

    Activin A is a member of the transforming growth factor beta (TGF-ß) family of proteins and functions to stimulate follicle-stimulating hormone (FSH) secretion. Activins are produced in many tissue types including the skin, gonads, lungs, and pituitary gland. Activins interact with receptor type I...

  • Recombinant Human CD40-Ligand

    CD40-Ligand, or CD154, is a membrane glycoprotein and differentiation antigen that is expressed on the surface of T cells, monocytes, basophils, eosinophils, platelets, dendritic cells, and endothelial cells. CD40-Ligand binds and activates the CD40 receptor on antigen-presenting cells. CD40-Ligand...

  • Recombinant Human / Mouse NT-3

    Neurotrophin-3 (NT-3) is an important member of the nerve growth factor (NGF) family of proteins. NT-3 promotes the growth, survival, and differentiation of neurons and synapses in the peripheral and central nervous systems. The receptor tyrosine kinase TrkC exclusively binds in high-affinity to...

  • Recombinant Mouse IL-33

    Interleukin 33 (IL-33) is a member of the IL-1 cytokine family and is constitutively expressed in smooth muscle and airway epithelial cells. IL-33 signals through the interleukin 1 receptor-like 1 (IL-1R1) and interleukin-1 receptor accessory protein (IL1RAP) receptors to ativate NF-?B and MAPK...

  • Recombinant Human R-SPONDIN-1

    R-Spondin-1 (RSPO-1) is a secreted growth factor that stabilizes ß-catenin and enhances WNT signaling. RSPO-1 is expressed in many tissues and regulates female sex determination, XX gonad development, oocyte differentiation, and hematopoietic stem cell specification. The RSPO-1 stabilization of...

  • Recombinant Mouse IL-31

    Interleukin 31 (IL-31) is an immunoregulatory cytokine that is expressed by activated type 2 T helper (Th2) cells. IL-31 signals through a heterodimer receptor consisting of the IL-31 Receptor A (IL-31RA) and the oncostatin M receptor (OSMR), which are expressed on monocytes, epithelial cells, and...

  • Recombinant Human IGF-II

    Insulin-like growth factor II (IGF-II) is an important fetal growth hormone made by theca cells during gestation. IGF-II engages the IGF-I receptor (IGF1R) to mediate embryonic growth. IGF-II also binds the sink IGF-II receptor (IGF2R) leading to IGF-II degradation.

  • Recombinant Human GALECTIN-3

    Galectin-3 belongs to the lectin family of carbohydrate binding proteins. Galectin-3 is expressed by a wide range of cell types including activated T cells, tumor cells, macrophages, osteoclasts, fibroblasts, and epithelial cells. Galectin-3 has specific binding affinity for beta-galactoside sugar...

  • Recombinant Human TGF-a

    Tumor growth factor alpha (TGF-a) is a member of the epidermal growth factor (EGF) family. TGF-a function is mediated through binding the EGF receptor (EGFR) to activate receptor tyrosine kinase signaling. TGF-a functions as a mitogen to activate epithelial cell proliferation, growth, and...

  • Recombinant Human SDF-1 a

    Stromal cell-derived factor-1 alpha (SDF-1 a), also called CXCL12a, is one of two SDF-1 splice variants made by a wide variety of cells upon stimulation by inflammatory cytokines such as TNF, IL-1, and LPS. SDF-1a signals through the G protein-coupled receptor CXCR4 to recruit activated leukocytes....

  • Mouse Th9 Cell Polarizing Recombinant Protein Bundle

    Cytokines for polarizing mouse T cells into Th9 cells. Th9 cells are a unique subset of T helper cells that produce IL-9. Although the exact function of IL-9 producing T cells is yet to be completely clear it is proposed that these cells could be important in inflammation and helminth infections....

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