IL-6 is an important pro-inflammatory and anti-inflammatory cytokine expressed by T cells, macrophages, and muscle cells. • Signals through a receptor complex containing two receptors, IL-6Ra and gp130 • Plays an important function in promoting fever and can serve to stimulate an immune response to trauma. IL-6 is often used for growth of hybridoma cell lines The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.
Bioactivity Assay:Proliferation of B9 cell ; ED50 =0.025 ng/mL; Bioactivity =1.2 x10^6 IU/µg