MP Biomedicals, Bottle, Glass, Amber, 1 g
MP Biomedicals
MP Biomedicals is a worldwide corporation manufacturing and distributing systems, kits and reagents for the life science research, medical device, biopharma manufacturing and diagnostics markets. Our extensive portfolio and custom services deliver the dependability that research and industrial communities rely on to worry less and discover more. From small scale research to large scale manufacturing, MP Biomedicals has been advancing life science projects for over 50 years.
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Retinoic Acid, All Trans Isomer
MP BiomedicalsRetinoic acid (RA) is a vitamin A-derived, non-peptidic, small lipophilic molecule that mediates the functions of vitamin A required for growth and development. It affects gene transcription and modulates a wide variety of biological processes like Cell Proliferation, Differentiation, including…
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ß-Nicotinamide Adenine Dinucleotide
MP Biomedicalsβ-NAD is one of the biologically active forms of nicotinic acid. Occurs in living cells, primarily in the oxidized state Coenzyme for dehydrogenases NAD usually acts as a hydrogen acceptor, forming NADH Major electron acceptor molecule in biological oxidations. Acts as a…
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Fluorescent Brightener 28
MP BiomedicalsFluorescent Brightner 28 is a colorless organic compound that fluoresces (clear bluish) under ultraviolet radiation. It is related structurally to Fluorescent Brightner 9 (Calcofluor White MR) which was used by Jefferies and Belcher and Maeda and Ischida in plant tissue studies. Fluorescent…
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Dexamethasone
MP BiomedicalsDexamethasone is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S…
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Trypsin from Beef Pancreas
MP BiomedicalsTrypsin consists of a single chain polypeptide of 223 amino acid residues. Member of the serine protease family Dissolves blood clots in its microbial form Treats inflammation in its pancreatic form Trypsin cleaves peptides on the C-terminal side of lysine and arginine residues.…
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Oleic Acid
MP BiomedicalsOleic acid is a mono-unsaturated omega-9 fatty acid created by dehydrogenation of stearic acid. It is then further dehydrogenated and elongated to create members of the n-9 family of fatty acids. Oleic acid is used as emollient. Small amounts of oleic acid are used as an excipient in…
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Collagenase Type II from Clostridium histolyticum
MP BiomedicalsCollagenases degrade native helical collagen fibrils. Plays an important role in connective tissue metabolism Produced by specific cells involved in repairs and remodeling processes Type II enzyme that contains greater clostripain activity Collagenase is used for collagen…
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Spectinomycin is an aminocyclitol antibiotic, closely related to the aminoglycosides, it inhibits protein synthesis (elongation) by interfering with peptidyl tRNA translocation. Mutation in rpsE (the gene for ribosomal protein S5) prevents binding of spectinomycin. Specinomycin is used in cell…
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Putrescine Dihydrochloride
MP BiomedicalsPutrescine is a biogenic polyamine and precursor of spermidine. It is formed via decarboxylation of ornithine or by decarboxylation of arginine followed by hydrolysis. Binds to the polyamine modulatory site of the NMDA receptor and potentiates NMDA-induced currents; precursor of spermidine.
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Guanosine-5'-Triphosphate Disodium Salt
MP BiomedicalsGuanosine-5'-triphosphate, a purine nucleotide, is required as a coenzyme for protein biosynthesis in a cell-free system. Guanosine 5′-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR)…
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Papain from Papaya Latex
MP BiomedicalsPapain is a sulfhydryl protease from Carica papaya latex. Cleaves peptide bonds of basic amino acids, leucine, or glycine Hydrolyzes esters and amides One unit will hydrolyze 1.0 µmole of N-alpha-benzoyl-L-arginine ethyl ester (BAEE) per minute at 25°C and pH 6.2 Papain…
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Kanamycin Monosulfate
MP BiomedicalsKanamycin sulfate is an antimicrobial agent effective against Gram-negative and Gram-positive bacteria and mycoplasma. It binds to the 70S ribosomal subunit, inhibits translocation, and elicits miscoding. Cross-resistance occurs between kanamycin and neomycin, framycetin, and paromomycin, and…
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Fetuin from Fetal Bovine Serum
MP BiomedicalsFetuin is a protein containing 12 Cys residues, all involved in disulfide bridges. The composition of bovine fetuin (weight %) is polypeptide 74%, hexose 8.3%, hexosamines 5.5%, and sialic acid 8.7%. Fetuin bovine is a protein with the ability to bind to the insulin receptor and inhibit insulin…
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Concanavalin A from Canavalia ensiformis seeds (jack beans)
MP BiomedicalsPure Canavalia ensiformis lectin (Con A) from Jackbean. Isolated by affinity chromatography on cross-linked dextran. Con A exists as a dimer below pH 5.0 and and at pH >7 it exists as a tetramer. Con-A is not a glycoprotein. The monomeric molecular weight of Con-A is 25,500. Con-A does not…
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Tricaprin
MP BiomedicalsSynonyms: 1,2,3-Tricaprinoylglycerol, 1,2,3-Tridecanoylglycerol, Glycerol tricaprate, Glycerol tris(decanoate), Tridecanoin, Glyceryl tridecanoate, 1,2,3-Tridecanoyl-rac-glycerol, Glyceryl tridecanoate, Tri-N-Caprin Molecular Formula: C33H62O6
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Spermidine
MP BiomedicalsSpermidine is biogenic polyamine formed from putrescine, a precursor of spermine. Spermidine has a role in cell growth processes and the formation and interconversion of spermidine in mammalian cells has been reported. Spermidine binds to and activates NMDA(N-Methyl-D-Aspartate receptor) and has…
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p-Nitophenol
MP Biomedicalsp-nitrophenol is used as an indicator in 0.1% alcohol solutions. 4-Nitrophenol is used as a precursor to prepare phenetidine, acetophenetidne and pH indicator. Its carboxylate ester derivatives are involved as an active component for the construction of amide moieties in peptide synthesis. It is…
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Hydroxypropyl ß-Cyclodextrin
MP Biomedicals2-Hydroxypropyl-beta-Cyclodextrin are non-toxic solubilizers. The solubility of drugs increases linearly with the concentration of 2-Hydroxypropyl-b-cyclodextrin in aqueous buffer. The formation of drug/cyclodextrin complexes is a rapidly reversible reaction and complexes exist both in solution and…
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o-Nitrophenyl-ß-D-Galactopyranoside
MP Biomedicalso-Nitrophenyl-β-D-galactoside (ONPG) is a colorimetric substrate for b-galactosidase. This product is hydrolyzed to o-nitrophenol by the enzyme. o-Nitrophenol is yellow in alkaline solution and can be quantitated at 410-420 nm 2 . o-Nitrophenyl-β-D-galactoside is a cell culture…
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5-Bromo-2'-Deoxyuridine
MP Biomedicals5-Bromo-2’-deoxyuridine is a thymidine analog and useful for the study of DNA synthesis where it is incorporated into DNA in place of thymidine. Measure DNA synthesis Label dividing cells Study cell signaling and processes that induce cell proliferation Used as a mutagen in…
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D-Biotin
MP BiomedicalsD-Biotin is a growth factor present in small amounts in every living cell. It is involved in naturally occurring carboxylation reactions. It occurs mainly bound to proteins or polypeptides. It is more abundant in the liver, kidney, pancreas, yeast and milk. Biotin levels are higher in cancerous…
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Rifamycin SV Sodium Salt
MP BiomedicalsRifamycin SV is a broad-spectrum semisynthetic antimicrobial agent of the rifamycin group. Rifamycin SV is used to study potential genes, such as rif15 and rif16, which may be involved in the conversion of rifamycin SV into rifamycin B. It is a potential treatment for traveler’s diarrhea…
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Phenazine Ethosulfate
MP BiomedicalsPhenazine ethosulfate is an intermediate which is used to detect nitric oxide reducatase activity in concert with ascorbic acid.
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Albumin from Human
MP BiomedicalsAlbumins are a group of simple proteins found in the body fluids and tissues of animals and in some plant seeds. Unlike globulins, albumins have low molecular weights, are soluble in water, are easily crystallized and contain an excess of acidic amino acids. Serum and plasma albumin is…
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ß-Nicotinamide Adenine Dinucleotide Phosphate Disodium Salt
MP Biomedicalsβ-NADP is a coenzyme necessary for the alcoholic fermentation of glucose and the oxidative dehydrogenation of other substances. It occurs widely in living tissue, especially in the liver. Nicotinic acid can be converted to nicotinamide in the body and, in this form, is found as a component of…
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Erythromycin
MP BiomedicalsErythromycin is a macrolide antibiotic that bind to the 50S ribosomal subunit and inhibit protein synthesis. This is an antimicrobial substance produced by the growth of certain strains of Streptomyces erythreus. It is a mixture consisting largely of erythromycin A with lesser amounts of…
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Nicotine Bitartrate Dihydrate
MP BiomedicalsNicotinic acetylcholine receptor agonist isolated from Nicotiana tabacum and Nicotiana rustica. Nicotine Tartrate finds an application as the nicotine active in a wide range of smoking cessation products such as nicotine lozenges and nicotine sub-lingual tablets. (-)-Nicotine ditartrate is a…
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N-Acetyl-D-Galactosamine
MP BiomedicalsN-Acetyl-D-galactosamine(GalNAc), an aminosugar, is a component of many O-linked and N-linked glycan structures. Intial O-linked sugar to many serine and threonine residues in protein glycosylations.
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2,3,5-Triphenyl Tetrazolium Chloride
MP Biomedicals2,3,5-Triphenyltetrazolium Chloride is a redox indicator. In the TTC assay (also known as TTC test or tetrazolium test), TTC is used to differentiate between metabolically active and inactive tissues. The white compound is enzymatically reduced to red TPF (1,3,5-triphenylformazan) in living tissues…
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Glutathione, Reduced
MP BiomedicalsGlutathione is the major low molecular weight thiol compound of the living plant or animal cell. It is a tripeptide with a gamma peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain. It is…
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Histamine Diphosphate Monohydrate
MP BiomedicalsHistamine Diphosphate Monohydrate is potent vasodilater. Endogenous H1 and H2 histamine receptor agonist; H1 activation mobilizes Ca2+; H22 activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.
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2,3,5-Triphenyltetrazolium Chloride
MP Biomedicals2,3,5-Triphenyltetrazolium Chloride is a redox indicator. In the TTC assay (also known as TTC test or tetrazolium test), TTC is used to differentiate between metabolically active and inactive tissues. The white compound is enzymatically reduced to red TPF (1,3,5-triphenylformazan) in living tissues…