PeptiGrowth

PG-007 exhibits functionality similar to that of Vascular Endothelial Growth Factor (VEGF), promoting endothelial cell proliferation and inducing differentiation of iPSCs into vascular endothelial cells. PG-007 exhibits selective binding affinity to VEGFR2 and acts as an agonist. Its phosphorylation...

PG-006, a selective inhibitor of BMP4, is a novel functional cyclic peptide capable of selectively inhibiting the signaling of the BMP4 family (BMP2, BMP4). This selective inhibition is not possible with existing small kinase inhibitors or Noggin. This peptide can be utilized for detailed analysis...

PG-007 exhibits functionality similar to that of Vascular Endothelial Growth Factor (VEGF), promoting endothelial cell proliferation and inducing differentiation of iPSCs into vascular endothelial cells. PG-007 exhibits selective binding affinity to VEGFR2 and acts as an agonist. Its phosphorylation...

Noggin is a BMP antagonist that supports the development of organoids derived from epithelial tissues, iPSCs, and ESC differentiation. It is commonly used for developing organoids of the intestine, pancreas, lung, and tumor-derived tissues, as well as for stem cell differentiation into neural and...

PG-008, a fully chemically synthesized peptide, comprises a heterodimer of two cyclic peptides with selective binding affinity for Frizzled and LRP5/6. Unlike Wnt3a, PG-008 lacks lipid moieties, making it highly soluble and eliminating handling difficulties. It exhibits superior activity to Wnt3a in...

Brain-derived neurotrophic factor (BDNF) is a growth factor derived from the brain that binds to TrkB receptors, regulating neuronal growth, survival, and synaptic function. PG-003, an alternative peptide to BDNF, is a chemically-synthesized homodimeric cyclic peptide with specific binding ability...

PG-010 is composed of a cyclic peptide that binds to the thrombopoietin receptor (TPOR) and functions as a growth factor substitute peptide, demonstrating agonistic activity towards TPOR. Recombinant TPO and PG-010 activities were compared using ERK phosphorylation and JAK2-STAT5 reporter gene...

Brain-derived neurotrophic factor (BDNF) is a growth factor derived from the brain that binds to TrkB receptors, regulating neuronal growth, survival, and synaptic function. PG-003, an alternative peptide to BDNF, is a chemically-synthesized homodimeric cyclic peptide with specific binding ability...

PG-005, a selective inhibitor of BMP7, is a novel functional cyclic peptide capable of selectively inhibiting the signaling of the BMP7 family (BMP5, BMP6, BMP7). This selective inhbition is not possible with existing small kinase inhibitors or Noggin. This peptide can be utilized for detailed...

PG-005, a selective inhibitor of BMP7, is a novel functional cyclic peptide capable of selectively inhibiting the signaling of the BMP7 family (BMP5, BMP6, BMP7). This selective inhbition is not possible with existing small kinase inhibitors or Noggin. This peptide can be utilized for detailed...

PG-010 is composed of a cyclic peptide that binds to the thrombopoietin receptor (TPOR) and functions as a growth factor substitute peptide, demonstrating agonistic activity towards TPOR. Recombinant TPO and PG-010 activities were compared using ERK phosphorylation and JAK2-STAT5 reporter gene...

PG-011 is composed of a cyclic peptide that has binding affinity for FGFR1c and exhibits agonist activity toward FGFR1c. We conducted a comparison of the cell proliferation activity of PG-011 and FGF2 using bone marrow-derived human MSCs (mesenchymal stem cells). The results showed that PG-011...

HGF (hepatocyte growth factor) is a growth factor involved in promoting the growth, survival, and regeneration of hepatocytes (liver cells) and other cell types, such as skeletal muscle satellite cells.PG-001, HGF alternative peptides, is a chemically-synthesized cyclic peptide homodimer that...

Signal inhibition of TGFβ1 is often used for stem cell reprogramming and iPSC differentiation. Small kinase inhibitors are commonly used, but they lack specificity and may perturb other signaling pathways, causing cytotoxicity. PG-002, a chemically-synthesized cyclic peptide with specific...

Noggin is a BMP antagonist that supports the development of organoids derived from epithelial tissues, iPSCs, and ESC differentiation. It is commonly used for developing organoids of the intestine, pancreas, lung, and tumor-derived tissues, as well as for stem cell differentiation into neural and...

PG-006, a selective inhibitor of BMP4, is a novel functional cyclic peptide capable of selectively inhibiting the signaling of the BMP4 family (BMP2, BMP4). This selective inhibition is not possible with existing small kinase inhibitors or Noggin. This peptide can be utilized for detailed analysis...

PG-008, a fully chemically synthesized peptide, comprises a heterodimer of two cyclic peptides with selective binding affinity for Frizzled and LRP5/6. Unlike Wnt3a, PG-008 lacks lipid moieties, making it highly soluble and eliminating handling difficulties. It exhibits superior activity to Wnt3a in...

Signal inhibition of TGFβ1 is often used for stem cell reprogramming and iPSC differentiation. Small kinase inhibitors are commonly used, but they lack specificity and may perturb other signaling pathways, causing cytotoxicity. PG-002, a chemically-synthesized cyclic peptide with specific...

HGF (hepatocyte growth factor) is a growth factor involved in promoting the growth, survival, and regeneration of hepatocytes (liver cells) and other cell types, such as skeletal muscle satellite cells.PG-001, HGF alternative peptides, is a chemically-synthesized cyclic peptide homodimer that...

PG-012 is a cyclic peptide that binds to FGFR2b and exhibits agonist activity toward FGFR2b. We compared the ERK phosphorylation activity and cell proliferation activity of PG-012 and KGF using human FGFR2b-overexpressing BaF3 cells. The results demonstrated that PG-012 exhibited ERK phosphorylation...