PG-012 is a cyclic peptide that binds to FGFR2b and exhibits agonist activity toward FGFR2b.
We compared the ERK phosphorylation activity and cell proliferation activity of PG-012 and KGF using human FGFR2b-overexpressing BaF3 cells. The results demonstrated that PG-012 exhibited ERK phosphorylation and cell proliferation activity comparable to KGF on a molar concentration basis. Due to the molecular weight difference, PG-012 achieves similar activity at approximately one-third of the KGF concentration when measured in ng/mL.
Provided as lyophilized powder
Purity: greater than or equal to95% (HPLC)
MW (Da): 6018.40 (acetate)
https://peptigrowth.com/en/products/pg-012/
This content is hosted by a third party (youtube.com). To view external content you must agree to cookies.