Bottle, Glass, Amber, 100 mg
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Guanosine-5'-Triphosphate Disodium Salt
MP BiomedicalsGuanosine-5'-triphosphate, a purine nucleotide, is required as a coenzyme for protein biosynthesis in a cell-free system. Guanosine 5′-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR)…
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L-Glutamic Acid-a-4-Nitroanilide
INDOFINE Chemical CompanyMF: C11H13N3O5 MF: 267.3 CAS: 24032-35-7 Purity: >99% by TLC
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Tamoxifen
MP BiomedicalsTamoxifen is a Protein Kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in…
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ß-Nicotinamide Adenine Dinucleotide Phosphate Disodium Salt
MP Biomedicalsβ-NADP is a coenzyme necessary for the alcoholic fermentation of glucose and the oxidative dehydrogenation of other substances. It occurs widely in living tissue, especially in the liver. Nicotinic acid can be converted to nicotinamide in the body and, in this form, is found as a component of…
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Linoleic Acid, Sodium Salt
MP BiomedicalsLinoleic acid (LA) is an unsaturated n-6 fatty acid; it belongs to one of the two families of essential fatty acids. The body cannot synthesize linoleic acid from other food components. Linoleic acid can be used to show the antioxidant effect of natural phenols.
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Deoxyribonuclease I from Bovine Pancreas
MP BiomedicalsDeoxyribonuclease from beef pancreas, DNase I, was first crystallized by Kunitz. It is an endonuclease which splits phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide yielding 5'-phosphate terminated polynucleotides with a free hydroxyl group on position 3'. The…
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ß-Nicotinamide Adenine Dinucleotide
MP Biomedicalsβ-NAD is one of the biologically active forms of nicotinic acid. Occurs in living cells, primarily in the oxidized state Coenzyme for dehydrogenases NAD usually acts as a hydrogen acceptor, forming NADH Major electron acceptor molecule in biological oxidations. Acts as a…
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Poly-L-Lysine Hydrobromide
MP BiomedicalsPoly-L-lysine is a positively charged amino acid polymer. Poly-lysine binds to DNA, red cell membrane and any negatively charged protein. It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell…
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Poly-D-Lysine Hydrobromide
MP BiomedicalsPoly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding. A compromise between the easier to use lower molecular weight products…
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Elastase from Porcine Pancreas
MP BiomedicalsElastase is an enzyme from the class of proteases (peptidases) that break down proteins. It hydrolyzes peptide bonds, especially those adjacent to neutral amino acids. Hydrolyses elastin Digests hemoglobin, casein, and fibrin One unit will solublize 1 mg of elastin in 20 minutes at…
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Trypsin from Beef Pancreas
MP BiomedicalsTrypsin consists of a single chain polypeptide of 223 amino acid residues. Member of the serine protease family Dissolves blood clots in its microbial form Treats inflammation in its pancreatic form Trypsin cleaves peptides on the C-terminal side of lysine and arginine residues.…
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Albumin from Human
MP BiomedicalsAlbumins are a group of simple proteins found in the body fluids and tissues of animals and in some plant seeds. Unlike globulins, albumins have low molecular weights, are soluble in water, are easily crystallized and contain an excess of acidic amino acids. Serum and plasma albumin is…
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Melatonin
MP BiomedicalsMelatonin is a hormone of the pineal gland. Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell…
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Hyaluronidase from Ovine Testes
MP BiomedicalsHyaluronidase is a glycoprotein containing 5% mannose and 2.17% glucosamine, it catalyzes the random hydrolysis of 1,4-linkages between 2-acetamido- 2-deoxy- β-D-glucose and D-glucose residues in hyaluronate. Hyaluronidase from bovine testes is a tetramer consisting of 4 equal subunits with a…
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Collagenase Type I from Clostridium histolyticum
MP BiomedicalsCollagenase is a protease which cleaves the triple-helical protein called collagen. There are three types of tissue collagenases, and these belong to the matrix metalloproteinases (MMP) family. Collagenase from Clostridium histolyticum has extensive use in biological studies, where it is used to…
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Chorionic Gonadotropin from Human Pregnancy Urine
MP BiomedicalsHuman chorionic gonadotropin (HCG), a polypeptide hormone produced by the human placenta, is composed of an alpha and a beta sub-unit. The alpha sub-unit is essentially identical to the alpha sub-units of the human pituitary gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone…
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Papain from Papaya Latex
MP BiomedicalsPapain is a sulfhydryl protease from Carica papaya latex. Cleaves peptide bonds of basic amino acids, leucine, or glycine Hydrolyzes esters and amides One unit will hydrolyze 1.0 µmole of N-alpha-benzoyl-L-arginine ethyl ester (BAEE) per minute at 25°C and pH 6.2 Papain…
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N-Acetyl-D-Galactosamine
MP BiomedicalsN-Acetyl-D-galactosamine(GalNAc), an aminosugar, is a component of many O-linked and N-linked glycan structures. Intial O-linked sugar to many serine and threonine residues in protein glycosylations.
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ß-Nicotinamide Adenine Dinucleotide Reduced Disodium Salt
MP Biomedicalsβ-NADH, a pyridine nucleotide and biologically active form of nicotinic acid, is a coenzyme necessary for the catalytic reaction of certain enzymes. β-NAD+ is a carrier for hydride ion, forming β-NADH. The hydride ion is enzymatically removed from a substrate molecule by the action…
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2',6'-Dihydroxy-4'-Methoxyacetophenone
INDOFINE Chemical CompanyMF: 182.18 CAS: 7507-89-3 Purity: >98%
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Hyaluronidase from Bovine Testes
MP BiomedicalsHyaluronidase is a glycoprotein containing 5% mannose and 2.17% glucosamine, it catalyzes the random hydrolysis of 1,4-linkages between 2-acetamido- 2-deoxy- b-D-glucose and D-glucose residues in hyaluronate. Hyaluronidase from bovine testes is a tetramer consisting of 4 equal subunits with a…
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Cefsulodin Sodium Salt
MP BiomedicalsCefsulodin is a third generation cephalosporin antibiotic that has very specific activity against Pseudomonas aeruginosa. It has no significant activity against other Gram-negative bacteria and very limited activity against Gram-positive bacteria and anaerobic bacteria. Cefuslodin is most…
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Lectin, Wheat Germ Agglutinin from Triticum vulgaris
MP BiomedicalsLectins are proteins or glycoproteins of non-immune origin that agglutinate cells and/or precipitate complex carbohydrates. Lectins are capable of binding glycoproteins even in presence of various detergents. The agglutination activity of these highly specific carbohydrate-binding molecules is…
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Poly-L-Lysine, MW >=70,000
MP BiomedicalsPoly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein. It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When…
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D-Biotin
MP BiomedicalsD-Biotin is a growth factor present in small amounts in every living cell. Involved in carboxylation reactions Occurs mainly bound to proteins or polypeptides Abundant in the liver, kideny, pancreas, yeast, and milk Levels are higher in cancerous tumors than in normal tissues …
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Collagenase Type IV from Clostridium histolyticum
MP BiomedicalsCollagenases degrade native helical collagen fibrils. It has an important role in connective tissue metabolism and is produced by specific cells involved in repairs and remodelling processes. Collagenase is used for tissue dissociation combined with other enzymes such as elastase, trypsin,…
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Heparin Sodium Salt from Porcine
MP BiomedicalsHeparin is a polymer classified as a mucopolysaccharide or a glycosoaminoglycan. It is biosynthesized and stored in mast cells of various mammalian tissues, particularly liver, lung and mucosa. It is made up of repeated disaccharide units consisting of 1,4-linked L-iduronic acid and D-glucosamine.…
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Fetuin from Fetal Bovine Serum
MP BiomedicalsFetuin is a protein containing 12 Cys residues, all involved in disulfide bridges. The composition of bovine fetuin (weight %) is polypeptide 74%, hexose 8.3%, hexosamines 5.5%, and sialic acid 8.7%. Fetuin bovine is a protein with the ability to bind to the insulin receptor and inhibit insulin…
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Dexamethasone
MP BiomedicalsDexamethasone is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S…
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Naloxone Hydrochloride
MP BiomedicalsNaloxone is specific and competitive opiate antagonist at mu, kappa, delta and sigma receptors; it blocks the action of sigma-agonists at opioid sites. It displaces morphine and other opiate agonists from the opiate receptor. It is more potent than Nalorphine and is also an effective antagonist for…