D-Biotin is a growth factor present in small amounts in every living cell.
- Involved in carboxylation reactions
- Occurs mainly bound to proteins or polypeptides
- Abundant in the liver, kideny, pancreas, yeast, and milk
- Levels are higher in cancerous tumors than in normal tissues
- Inactivated by binding to avidin
D-Biotin may be used to elute proteins from avidin/streptavidin resins. It is widely used for dietary supplements and fortified foods. It is also used for tablets and hard-shell capsule preparation due to its pharmaceutical properties.
Essential vitamin that is important for amino acid and energy metabolism, and fatty acid synthesis. It is a prosthetic group in four mammalian carboxylase families and facilitates the binding and transfer of carbon dioxide.
Purity: ≥97.5%
Key Applications: Elute proteins, Dietary supplements, Preparation of tablets and capsules
Application Areas: Molecular biology
Product Type: Biochemicals
Biochemical Category: Pharmaceuticals
Density: 1.267 g/cm3(Lit.)
Boiling Point: 573.6°C at 760 mmHg(Lit.)
Melting Point: 223 - 233°C
Optical Rotation: +89 to +93° (c=2, 0.1 N NaOH)
Refractive Index: 90.5° (C=2, 0.1mol/L NaOH)(Lit.)
Presentation: White Crystalline Powder
Format: White Crystalline Powder
Isoelectric point (pI): 3.5(lit.)
Detection Method: FTIR
NOTES: Reaction (0.02% aq soln)- Very Slightly Acidic to Litmus
Solubility: Soluble in water (22 mg/100 mL), ethanol (80 mg/100 mL), more soluble in hot water and in dilute alkalies; insoluble in other common organic solvents. Soluble in 2 M Ammonium hydroxide (50 mg/mL - clear, colorless solution), dimethylformamide (1.7 mg/mL).
Storage & Handling: Store at +4°C.