Histamine Diphosphate Monohydrate is potent vasodilater. Endogenous H1 and H2 histamine receptor agonist; H1 activation mobilizes Ca2+; H2₂ activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.

Tamoxifen is a Protein Kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in…

Oleic acid is a mono-unsaturated omega-9 fatty acid created by dehydrogenation of stearic acid. It is then further dehydrogenated and elongated to create members of the n-9 family of fatty acids. Oleic acid is used as emollient. Small amounts of oleic acid are used as an excipient in…

n-Octyl-β-D-Glucopyranoside is a non-ionic detergent for membrane protein. n-Octyl-glucoside is a non-ionic alkyl-glucoside detergent commonly used in the solubilization of membrane proteins and phospholipids. n-Octyl-glucoside has been used at a molar dependant ratios for the…

Safranine O is a biological stain used in histology, cytology, bacteriology. It is a redox and adsorption indicator.

β-NADP is a coenzyme necessary for the alcoholic fermentation of glucose and the oxidative dehydrogenation of other substances. It occurs widely in living tissue, especially in the liver. Nicotinic acid can be converted to nicotinamide in the body and, in this form, is found as a component of…

Physiological chelating agent for heavy metals. It is used as an antirheumatic and as a chelating agent in Wilson′s disease. It is used as a copper chelator to form mixed disulfides with cysteine or other sulfide media components. It is used to inactivate protein-1 DNA binding and to…

Melatonin is a hormone of the pineal gland. Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell…

5-Bromo-2’-deoxyuridine is a thymidine analog and useful for the study of DNA synthesis where it is incorporated into DNA in place of thymidine. Measure DNA synthesis Label dividing cells Study cell signaling and processes that induce cell proliferation Used as a mutagen in…

Ampicillin is a semi-synthetic derivative of penicillin, active as a broad-spectrum antibiotic. It is inactivated by beta-lactamases and for this reason a beta-lactamase inhibitor should be considered when using ampicillin. Against gram-positive bacteria, ampicillin has a similar mode of action as…

Nalidixic acid sodium salt is an antibacterial agent (synthetic quinolone antibiotic), which is inhibitor of bacterial DNA polymerase (DNA gyrase) & avian myeloblastoma virus reverse transcriptase. Inhibits nucleic acid and protein synthesis in Saccharomyces cerevisiae. Typically used at a…

Retinoic acid (RA) is a vitamin A-derived, non-peptidic, small lipophilic molecule that mediates the functions of vitamin A required for growth and development. It affects gene transcription and modulates a wide variety of biological processes like Cell Proliferation, Differentiation, including…

(TMB Powder) This product is excellent for ELISA procedures. C₁₆H₂₀N₂ MW 240.3

D-Biotin is a growth factor present in small amounts in every living cell. Involved in carboxylation reactions Occurs mainly bound to proteins or polypeptides Abundant in the liver, kideny, pancreas, yeast, and milk Levels are higher in cancerous tumors than in normal tissues …

A vitamin/enzyme cofactor found in milk, eggs, malted barley, liver, kidney, heart, leafy vegetables. Richest natural source is yeast. Occurs in the free form only in the retina of the eye, in whey, and in urine; bioactive forms occurring in tissues and cells are riboflavin monophosphate and…

Lysozyme (muramidase) hydrolyzes preferentially the β-1,4 glucosidic linkages between N-acetylmuramic acid and N-acetylglucosamine which occur in the mucopeptide cell wall structure of certain microorganisms, such as Micrococcus lysodeikticus. Extracts group specific antigens …

D-Biotin is a growth factor present in small amounts in every living cell. It is involved in naturally occurring carboxylation reactions. It occurs mainly bound to proteins or polypeptides. It is more abundant in the liver, kidney, pancreas, yeast and milk. Biotin levels are higher in cancerous…

N-Acetyl-L-cysteine is an acetylated amino acid with antioxidant and mucolytic properties for isolation of mycobacteria from sputum. As a mucolytic agent, N-Acetyl-L-cysteine serves to dissipate disulfide bonds across mucoproteins, loosening and clearing the viscosity of sputum. …

o-Nitrophenyl-β-D-galactoside (ONPG) is a colorimetric substrate for b-galactosidase. This product is hydrolyzed to o-nitrophenol by the enzyme. o-Nitrophenol is yellow in alkaline solution and can be quantitated at 410-420 nm 2 . o-Nitrophenyl-β-D-galactoside is a cell culture…

Putrescine is a biogenic polyamine and precursor of spermidine. It is formed via decarboxylation of ornithine or by decarboxylation of arginine followed by hydrolysis. Binds to the polyamine modulatory site of the NMDA receptor and potentiates NMDA-induced currents; precursor of spermidine.

N-(1-Naphthyl)ethylenediamine, dihydrochoride is used for colorimetric determination of sulfonamide in blood. It is used for spectrophotometric determiniation of nitrite and nitrate. It is also used as a coupling agent for the spectrophotometric determination of aminophenols, phenylenediamines,…

Coomassie Blue R-250 is a triphenylmethane dye used extensively in SDS-PAGE for the analysis of proteins. Brilliant Blue R has been used for many years for staining proteins on polyacrylamide electrophoresis gels. Improvement of sensitivity and background have been accomplished using Brilliant…

β-NADH, a pyridine nucleotide and biologically active form of nicotinic acid, is a coenzyme necessary for the catalytic reaction of certain enzymes. β-NAD+ is a carrier for hydride ion, forming β-NADH. The hydride ion is enzymatically removed from a substrate molecule by the action…

p-nitrophenol is used as an indicator in 0.1% alcohol solutions. 4-Nitrophenol is used as a precursor to prepare phenetidine, acetophenetidne and pH indicator. Its carboxylate ester derivatives are involved as an active component for the construction of amide moieties in peptide synthesis. It is…

Metronidazole ia an antiprotozoal (Trichomonas), a limited spectrum antibiotic that actively deters the growth of protozoa, anaerobic gram-positive, and anaerobic gram-negative bacteria. Metronidazole suppress protozoans such as Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis.…

β-NAD is one of the biologically active forms of nicotinic acid. Occurs in living cells, primarily in the oxidized state Coenzyme for dehydrogenases NAD usually acts as a hydrogen acceptor, forming NADH Major electron acceptor molecule in biological oxidations. Acts as a…

N-Acetyl-D-galactosamine(GalNAc), an aminosugar, is a component of many O-linked and N-linked glycan structures. Intial O-linked sugar to many serine and threonine residues in protein glycosylations.

Kanamycin sulfate is an antimicrobial agent effective against Gram-negative and Gram-positive bacteria and mycoplasma. It binds to the 70S ribosomal subunit, inhibits translocation, and elicits miscoding. Cross-resistance occurs between kanamycin and neomycin, framycetin, and paromomycin, and…

Amikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections. Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth. Amikacin must be given by the…

L-Tryptophan is an amino acid precursor of serotonin and melatonin.

Evans Blue is a potent inhibitor of L-glutamate uptake into synaptic vesicles via EAAT. Evans Blue also inhibits AMPA and kainate receptor-mediated currents (IC50 values are 220 and 150 nM respectively). The compound is also a P2X-selective purinoceptor antagonist. Evans Blue used in…

Pullulan, edible plastic excellent in adhesivenss and film formability. Pullulan is a natural neutral polysaccharide produced from starch by cultivating a black yeast. Pullulan has been used in a study to assess bone tissue engineering. It has also been used in a study that investigated anti-fog applications.