A light-generating enzyme that catalyzes an oxidative reaction, using luciferin, ATP, and molecular oxygen to produce oxyluciferin, which yields visible light.

Source: Recombinant protein expressed in E. coli MW: 12.5 kDa

Source: one ampoule contains recombinant rat Trx1

Source: Active recombinant N-terminal His-tagged protein expressed in Sf21 insect cells MW: 118.3 kDa

Active recombinant N-terminal GST-tagged protein expressed in E. coli • G9a-like protein (GLP) is a SET domain-containing methyltransferases that specifically mono- and di-methylate histone H3 at lysine 9 (H3K9).

Source: Recombinant protein expressed in E. coli WDR5 has been demonstrated to bind histone H3 by recognizing the first three amino acids of the N-terminal tail. Binding of WDR5 to a conserved arginine-containing motif in MLL-1, the so-called WDR5 interaction (“Win”) motif, promotes…

Source: Recombinant N-terminal GST-tagged protein expressed in E. coli MW: 37.9 kDa

MW: 135 kDa Source: recombinant enzyme; isolated from a Baculovirus overexpression system in Sf9 cells

Source: Recombinant N-terminal GST-tagged enzyme expressed in E. coli Mr: 60.6 kDa (GST-tag); 26 kDa (native) SIRT5 is located in the mitochondrial matrix and its functions are largely still being elucidated, however a few promising substrates have been studied. SIRT5 has been shown to…

Source: Active recombinant N-terminal His-tagged enzyme amino acids 101-399 purified from E. coli Mr: 37 kDa (theoretical); 33.5 kDa (observed) SIRT3, is a mitochondrial protein that is synthesized as an enzymatically inactive protein. Human SIRT3 is activated by a matrix-processing…

Source: recombinant N-terminal hexahistidine-tagged protein expressed in E. coli Mr: 19.1 kDa

Source: recombinant C-terminal histidine-tagged protein expressed using a baculovirus overexpression system in Sf21 cells Mr: 98.8 kDa A secreted lysophospholipase D that catalyzes the hydrolysis of LPC to generate LPA; ATX-LPA signaling is involved in a range of pathologies including tumor…

Source: Recombinant human N-terminal GST-tagged protein expressed in E. coli amino acids 1,717-1,972 (N- and C-terminal truncation)

Source: Active recombinant N-terminal His-tagged protein expressed in E. coli Mr: 44.6 kDa

Source: Purified from human plasma Mr: α chain isoform 1 (95 kDa), α chain isoform 2 (69.8 kDa), β chain (55.9 kDa) and isoform γ-B chain (51.5 kDa)

A cytotoxin that inactivates host Rho family GTPases by glucosylation, altering cytoskeletal structure, cell division, and cell-cell adhesion.

Source: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 38.2 kDa

Source: Recombinant N-terminal His-tagged protein expressed in Sf21 cells Mr: 53.5 kDa EED is a WD40 repeat-containing protein that forms part of the Polycomb repressive complex 2 (PRC2). The EED subunit does not contain methyltransferase activity. However, transcriptional repression by…

Source: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 39.89 kDa

Source: Recombinant protein expressed in E. coli Mr: 15.5 kDa Histone H3 is one of the core nucleosomal histones. It undergoes many modifications which include acetylation, methylation, and phosphorylation that are important for regulation of gene transcription.

Isolated from ram seminal vesicles.

Source: Active human recombinant C-terminal His-tagged protein preceded by a linker region and V5 epitope expressed in E. coli Mr: 34 kDa

Recombinant protein expressed in E. coli DPY-30 is a component of the MLL1 methylation complex, which interacts directly with Ash2L.

Source: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 41.2 kDa BRDT shares homology with the RING3 protein. The two bromodomains of BRDT recognize acetylated histone H4. Loss of BRDT leads to defects in spermatogenesis. In addition to testis specific expression, BRDT was…

Source: Recombinant protein expressed in E. coli MW: 12.6 kDa

Protein Arginine Deiminases (PADs) are guanidino-modifying enzymes belonging to the amidinotransferase superfamily and are designated PAD1-4 and PAD6. PAD enzymes catalyze the conversion of specific arginine residues to citrulline in a calcium-dependent manner. All enzymes are cytosolic except for…

Source: Active recombinant N-terminal His-tagged protein expressed in Sf21 cells Mr: 96.3 kDa Recombinant Gcn5 preferentially acetylates lysine 14 on histone H3 in vitro; however, alone it is unable to acetylate nucleosomal core histone substrates. Acetylation of the nucleosomal histones…

Source: Recombinant N-terminal His- and SUMOpro-tagged protein expressed in E. coli Mr: 34.5 kDa

A mixture of H1, H2a, H2b, H3, and H4 histones isolated from calf thymus.

Source: Recombinant protein expressed in E. coli Mr: 45.6 kDa

Streptavidin conjugated to Alkaline Phosphatase Binding Moiety: Streptavidin Enzyme: Alkaline Phosphatase Uses: Western blot detection. Recommended dilution of 1:500-1:10,000. Starting dilution: 1:2,000.

Source: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 42.6 kDa This product contains the tudor domain of TP53BP1. Binding of TP53BP1 to dimethylated lysine 382 on p53 (p53 K382me2), as well as histone H4K20me2, through the tudor domain, has been shown to be important for…