Protein

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  • HDAC1 (human recombinant)

    Cayman Chemical

    Source: 50 µg of full length recombinant C-terminal His- and FLAG-tagged protein expressed in baculovirus expression system Mr: 56 kDa HDAC1 is a Class I HDAC that catalyzes the deacetylation of core histones and other non-histone proteins to control complex biological events, including…

  • Streptavidin:HRP

    Cayman Chemical

    Streptavidin HRP Binding Moiety: Streptavidin Enzyme: Horseradish Peroxidase Uses: Western blot detection. Recommended dilution of 1:500-1:10,000. Starting dilution: 1:2,000.

  • SET8 (human recombinant)

    Cayman Chemical

    Source: Active recombinant N-terminal His-tagged protein amino acids 190-352, expressed in E. coli Mr: 21.1 kDa SET8 selectively mono-methylates histone H4 at lysine 20, an event proven to have an important role in chromatin structure and transcriptional activation. SET8 is also a novel…

  • Source: Active recombinant C-terminal His-tagged protein expressed in E. coli Mr: ~37 kDa Protein concentration: 0.8 mg/ml Human PGFS catalyzes the isomerization of PGH2 to PGF2a (PGH2 9,11-endoperoxide reductase activity), as well as the formation of 11b-PGF2a from PGD2 (PGD2…

  • Source: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 53.3 kDa

  • JMJD2D (human recombinant)

    Cayman Chemical

    Active recombinant N-terminal His-tagged protein expressed in E. coli JMJD2D catalyzes the demethylation of di- and tri-methylated forms of histone H3 at lysine residue 9 (me2/3), leading to transcriptional repression and activation, respectively.

  • COX-2 (ovine recombinant)

    Cayman Chemical

    Recombinant protein expressed in Sf21 cells using the Baculovirus system One unit is defined as the amount of enzyme required to consume 1 nmol of oxygen per minute 37°C in 100 mM Tris, pH 8.0, containing 100 µM arachidonate, 5 mM EDTA, 2 mM phenol, and 1 µM hematin.

  • Source: Fibrinogen purified from human plasma citrullinated with human recombinant PAD4 plasma Uncitrullinated Fibrinogen Mr: α chain isoform 1 (95 kDa), α chain isoform 2 (69.8 kDa), β chain (55.9kDa) and isoform γ-B chain (51.5 kDa)

  • FABP7 (human recombinant)

    Cayman Chemical

    Source: recombinant N-terminal hexahistidine-tagged protein expressed in E. coli Mr: 19.1 kDa

  • Source: Active recombinant enzyme expressed in E. coli MW: 46 kDa Lipocalin-type prostaglandin D synthase (L-PGDS) catalyzes the isomerization of PGH2 to produce PGD2 and acts as a carrier protein for lipid-like molecules (i.e., retinoids and thyroid hormones).

  • Source: Active human recombinant N-terminal GST-tagged protein expressed in E. coli MW: 55 kDa NAD+-dependent 15-PGDH catalyzes the oxidation of PGs to 15-keto metabolites that have greatly reduced biological activity. Three different studies have shown an inverse correlation between 15-PGDH…

  • Source: recombinant N-terminal GST-tagged protein purified from E. coli Mr: ~41.7 kDa (15.4 kDa native; 26.3 kDa GST-tagged) PtdIns-(3,4,5)-P3 Binding Protein contains a highly specific PH domain that recognizes and binds PtdIns-(3,4,5)-P3. PtdIns phosphates play a critical role in the…

  • An enterotoxin that inactivates host Rho family GTPases by glucosylation, altering cytoskeletal structure, cell division, and cell-cell adhesion.

  • HDAC4 (human recombinant)

    Cayman Chemical

    Source: 10 µg of recombinant N-terminal GST-tagged protein expressed in baculovirus expression system Mr: 75.2 kDa HDAC4 is a Class IIa HDAC that can shuttle between the nucleus and cytoplasm, suggesting potential extranuclear functions by regulating the acetylation status of nonhistone substrates.

  • Streptavidin conjugated to Alkaline Phosphatase Binding Moiety: Streptavidin Enzyme: Alkaline Phosphatase Uses: Western blot detection. Recommended dilution of 1:500-1:10,000. Starting dilution: 1:2,000.

  • HDAC8 (human recombinant)

    Cayman Chemical

    Source: Active recombinant C-terminal His-tag expressed in E. coli MW: 45.3 kDa HDAC8 is a Class I HDAC that catalyzes the deacetylation of core histones, resulting in tightening of nucleosomal integrity, restricting access to transcription factors, and suppression of transcription. It can…

  • Active recombinant N-terminal GST-tagged protein expressed in E. coli • G9a-like protein (GLP) is a SET domain-containing methyltransferases that specifically mono- and di-methylate histone H3 at lysine 9 (H3K9).

  • eIF4E (human recombinant)

    Cayman Chemical

    Source: Recombinant protein expressed in E. coli Mr: 25.2 kDa

  • An intact toxin that catalyzes the ADP-ribosylation and inactivation of EF-2, terminating protein synthesis and causing cell death.

  • Adenosine Receptor A2A is a multi-pass membrane protein that is normally localized to the plasma membrane. This receptor is part of the G-protein coupled receptor family that binds adenosine and keeps it in equilibrium inside and outside the cell. Along with establishing this…

  • Renin (human recombinant)

    Cayman Chemical

    Active enzyme for drug discovery research.

  • CBX3 (human recombinant)

    Cayman Chemical

    Source: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 48.4 kDa

  • Source: Recombinant protein expressed in E. coli Mr: 15.5 kDa Histone H3 is one of the core nucleosomal histones. It undergoes many modifications which include acetylation, methylation, and phosphorylation that are important for regulation of gene transcription.

  • MIF (human recombinant)

    Cayman Chemical

    Source: Recombinant protein expressed in E. coli MW: 12.6 kDa

  • Source: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 42.2 kDa

  • JMJD2A (human recombinant)

    Cayman Chemical

    Source: Active recombinant N-terminal His-tag protein expressed in E. coli Mr: 43 kDa JMJD2A catalyzes the demethylation of trimethylated histone at lysine residues 9 and 36.

  • HDAC2 (human recombinant)

    Cayman Chemical

    Source: 50 µg of full length recombinant C-terminal His-tagged protein expressed in baculovirus expression system Mr: 56 kDa HDAC2 is a Class I HDAC that catalyzes the deacetylation of core histones, resulting in tightening of nucleosomal integrity, restricting access to transcription…

  • eNOS (bovine recombinant)

    Cayman Chemical

    MW: 135 kDa Source: recombinant enzyme; isolated from a Baculovirus overexpression system in Sf9 cells

  • CBX5 (human recombinant)

    Cayman Chemical

    Source: Recombinant N-terminal His-tagged protein expressed in E. coli

  • Source: 250 µg of human recombinant Grx1

  • Source: Purified from human plasma, citrullinated with human recombinant PAD2 MW: α chain isoform 1 (95 kDa), α chain isoform 2 (69.8 kDa), β chain (55.9k Da), and,isoform γ-B chain (51.5 kDa)

  • SIRT6 (human recombinant)

    Cayman Chemical

    Source: Active recombinant N-terminal His-tagged enzyme amino acids 1-355 expressed in E. coli Mr: 43.7 kDa SIRT6 associates specifically with telomeres and functions at chromatin to decrease NF-κB signaling. Mammalian cells depleted of SIRT6 display abnormal telomere structures similar…

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