Source: recombinant protein N-terminal His-tag expressed in E. coli Mr: 19 kDa Protein concentration: 0.5 mg/ml

Source: Active recombinant N-terminal His-tagged protein amino acids 190-352, expressed in E. coli Mr: 21.1 kDa SET8 selectively mono-methylates histone H4 at lysine 20, an event proven to have an important role in chromatin structure and transcriptional activation. SET8 is also a novel…

Source: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 35.5 kDa

Active recombinant N-terminal GST-tagged protein expressed in E. coli • G9a-like protein (GLP) is a SET domain-containing methyltransferases that specifically mono- and di-methylate histone H3 at lysine 9 (H3K9).

Source: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 48.4 kDa

Active, pure recombinant enzyme.

A multimeric enterotoxin that catalyzes the ADP-ribosylation of the Gsα protein, which activates adenylate cyclase and increases the intracellular concentration of cAMP; causes the hypersecretion of chloride and bicarbonate ions, which results in increased fluid secretion and the severe…

Source: one ampoule contains salt-free GRX from E. coli Mr: 10 kDa

Source: Recombinant protein expressed in E. coli MW: 12.5 kDa

An intact toxin that catalyzes the ADP-ribosylation and inactivation of EF-2, terminating protein synthesis and causing cell death.

Source: recombinant protein expressed in Sf21 cells Mr: 54 kDa PPARs are members of the nuclear receptor family of ligand activated transcription factors that heterodimerize with retinoic acid like receptors, regulating gene expression and differentiation. PPARδ is a mediator of diverse…

Streptavidin HRP Binding Moiety: Streptavidin Enzyme: Horseradish Peroxidase Uses: Western blot detection. Recommended dilution of 1:500-1:10,000. Starting dilution: 1:2,000.

Nitrotyrosine BSA is a positive control for detection of protein tyrosine nitration by WB using nitrotyrosine antibodies.

Source: 50 µg of a complex of full length recombinant C-terminal His-tagged HDAC3 and recombinant N-terminal GST-tagged NCOR2 amino acids 395-489, co-expressed in baculovirus expression system Mr: 49.7 kDa (HDAC3); 37.6 kDa (NCOR2) HDAC3 is a Class I HDAC that is inactive alone and…

Source: Human blood; all source material tested and found non-reactive to HTLV-III and HBsAg using FDA approved assay methods Mr: 38 kDa

Recombinant enzyme isolated from a Baculovirus overexpression system in Sf21 cells.

Source: Active recombinant N-terminal His-tagged enzyme isolated from a HEK293 overexpression system MW: 71 kDa (~16 & 63 kDa purified) PCSK9 is a member of the subtilisin serine protease family with an important role in lipoprotein metabolism. Mutation in the PCSK9 gene is associated…

EC 3.1.1.4 Active enzyme isolated from bee venom One unit of enzyme hydrolyzes one µmol of Diheptanoyl Thio-PC per minute at 25°C PLA2 catalyzes the hydrolysis of fatty acids at the sn-2 position of glycerophospholipids, yielding a free fatty acid and a lysophospholipid. PLA2…

Source: Recombinant N-terminal His- and SUMOpro-tagged protein expressed in E. coli Mr: 34.5 kDa

Source: Recombinant human N-terminal GST-tagged protein expressed in E. coli amino acids 1,717-1,972 (N- and C-terminal truncation)

Each vial contains nNOS (rat) to be used as a standard for WB and electrophoresis. The enzyme has been carefully purified to exclude all unrelated proteins; may not be catalytically active.

Source: Active recombinant N-terminal Strep II-tagged protein expressed in E. coli Mr: 40.8 kDa JMJD2E catalyzes the demethylation of histone H3 at lysince residue 9. JMJD2E is an α-ketoglutarate-dependent Fe (II) oxygenase. Purification of Fe-dependent JmjC family members by IMAC can…

Source: Human recombinant PP2A catalytic subunit expressed in insect cells with an N-terminal octahistidine-tag followed by a streptactin-tag. The C-terminal leucine 309 was deleted. MW: 38.6 kDa PP2A is a divalent cation-independent protein serine/threonine phosphatase involved in regulating…

Source: Active human recombinant N-terminal His-tagged protein purified from Sf21 cells Mr: 50.8 kDa PTEN functions as a key regulatory enzyme in many signal transduction pathways by dephosphorylating proteins and lipids such as Akt and PIP3. Mutation of PTEN results in many human cancers…

Spectral Characteristics: Visible absorption maximum = 483 nm, Emission maximum = 673 nm; Peridinin Chlorophyll (PerCP), crosslinked with SMCC for stability.

Source: Recombinant N-terminal His-tagged protein expressed in E. coli MW: 40.48 kDa Annexin A1 is an endogenous mediator of inflammation, promoting resolution in a number of ways. Normally expressed in intracellular compartments, it is drawn to the cell membrane and both induced and…

Source: one ampoule contains 100 µg of salt-free recombinant mouse cytosolic thioredoxin Activity: fully active with mammalian thioredoxin reductase

Adenosine Receptor A_2A is a multi-pass membrane protein that is normally localized to the plasma membrane. This receptor is part of the G-protein coupled receptor family that binds adenosine and keeps it in equilibrium inside and outside the cell. Along with establishing this…

The principal cytotoxic component of bee venom; assembles as tetramers on membrane surfaces to form pores, resulting in cell death.

Source: recombinant N-terminal GST-tagged protein purified from E. coli Mr: ~41.7 kDa (15.4 kDa native; 26.3 kDa GST-tagged) PtdIns-(3,4,5)-P3 Binding Protein contains a highly specific PH domain that recognizes and binds PtdIns-(3,4,5)-P3. PtdIns phosphates play a critical role in the…

Source: recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 41.4 kDa The isolated individual or tandem bromodomains of BRD4 have been shown to bind acetylated histone tails, serving to couple histone acetylation marks to the transcriptional regulation of target promoters.

Source: Recombinant N-terminal His-tagged protein expressed in Sf21 cells Mr: 53.5 kDa EED is a WD40 repeat-containing protein that forms part of the Polycomb repressive complex 2 (PRC2). The EED subunit does not contain methyltransferase activity. However, transcriptional repression by…