Active recombinant N-terminal GST-tagged protein expressed in E. coli • G9a-like protein (GLP) is a SET domain-containing methyltransferases that specifically mono- and di-methylate histone H3 at lysine 9 (H3K9).

Source: one ampoule contains salt-free GRX from E. coli Mr: 10 kDa

An intact toxin that catalyzes the ADP-ribosylation and inactivation of EF-2, terminating protein synthesis and causing cell death.

Adenosine Receptor A_2A is a multi-pass membrane protein that is normally localized to the plasma membrane. This receptor is part of the G-protein coupled receptor family that binds adenosine and keeps it in equilibrium inside and outside the cell. Along with establishing this…

Source: recombinant N-terminal GST-tagged protein purified from E. coli Mr: ~45.2 kDa (18.9 kDa native; 26.3 kDa GST-tagged) PtdIns-(4,5)-P2 Binding Protein contains a highly specific PH domain that recognizes and binds PtdIns-(4,5)-P2. PtdIns-(4,5)-P2 can be phosphorylated by…

An inactive neurotoxin used as a vaccine to produce immunity to tetanus; functions as a carrier of conjugated polysaccharides in the development of vaccines against encapsulated bacterial pathogens.

A multimeric enterotoxin that catalyzes the ADP-ribosylation of the Gsα protein, which activates adenylate cyclase and increases the intracellular concentration of cAMP; causes the hypersecretion of chloride and bicarbonate ions, which results in increased fluid secretion and the severe…

Source: Human blood; all source material tested and found non-reactive to HTLV-III and HBsAg using FDA approved assay methods Mr: 38 kDa

Recombinant C-terminal His-tagged protein expressed in E. coli One unit is defined as the amount of enzyme required to reduce 1 µmol of NADP+ to NADPH per minute at 25°C in 50 mM Triethanolamine, pH 7.6, containing 1 mM MgCl₂.

Source: Active recombinant C-terminal His-tagged protein expressed in E. coli MW: 47.9 kDa

Source: Purified from human plasma, citrullinated with human recombinant PAD2 MW: α chain isoform 1 (95 kDa), α chain isoform 2 (69.8 kDa), β chain (55.9k Da), and,isoform γ-B chain (51.5 kDa)

Streptavidin HRP Binding Moiety: Streptavidin Enzyme: Horseradish Peroxidase Uses: Western blot detection. Recommended dilution of 1:500-1:10,000. Starting dilution: 1:2,000.

MW: 135 kDa Source: recombinant enzyme; isolated from a Baculovirus overexpression system in Sf9 cells

GPR17 is a G protein-coupled receptor that has been identified as a dualistic receptor recognizing signals from two unrelated chemical families: nucleotides and cysteinyl leukotrienes (CysLTs). The deorphanization of GPR17 supports the suggested crosstalk between nucleotides and CysLTs during…

Source: Recombinant protein expressed in E. coli Mr: 15.5 kDa Histone H3 is one of the core nucleosomal histones. It undergoes many modifications which include acetylation, methylation, and phosphorylation that are important for regulation of gene transcription.

A control peptide for tests that use Cayman’s β-Amyloid (1-8, A2V) Peptide (Item No. 10229).

Source: recombinant protein expressed in E. coli. An N-terminal His-tag and SUMOpro tag were removed by cleavage with SUMO protease 1 (Ulp1). Mr: 12.4 kDa

Recombinant protein expressed in E. coli MLL1 plays a major role in epigenetic regulation through methylation of histone 3 at lysine 4 (H3K4) to activate gene transcription.

Source: recombinant N-terminal hexahistidine-tagged protein expressed in E. coli Mr: 19.3 kDa Protein concentration: 1.0 mg/ml

Source: Recombinant GST-tagged protein expressed in E. coli Mr: 71.2 kDa The isolated individual or tandem bromodomains of BRD2 have been shown to bind acetylated histone tails, serving to couple histone acetylation marks to the transcriptional regulation of target promoters.

Source: 50 µg of full length recombinant C-terminal His- and FLAG-tagged protein expressed in baculovirus expression system Mr: 56 kDa HDAC1 is a Class I HDAC that catalyzes the deacetylation of core histones and other non-histone proteins to control complex biological events, including…

Source: Active recombinant N-terminal His-tagged protein amino acids 190-352, expressed in E. coli Mr: 21.1 kDa SET8 selectively mono-methylates histone H4 at lysine 20, an event proven to have an important role in chromatin structure and transcriptional activation. SET8 is also a novel…

Source: Recombinant protein expressed in E. coli Mr: 13.9 kDa Histone 2A is one of the four histones that comprise a nucleosome protein core.

Dieosinediglutathione is the product of glutathione disulfide and eosin isothiocyanate which has been purified and lyophilized. This glutathione disulfide derivative has low fluorescence due to self-quenching. The monomer eosinglutathione (EGSH) has high fluorescence. This product can be used for…

Source: Recombinant N-terminal His-tagged protein expressed in E. coli Mr: 16.6 kDa The isolated individual or tandem bromodomains of BRD4 have been shown to bind acetylated histone tails, serving to couple histone acetylation marks to the transcriptional regulation of target promoters.

Source: Active recombinant N-terminal His-tagged protein expressed in Sf21 cells Mr: 43.7 kDa PRMT6 is a nuclear type-1 PRMT, catalyzing the formation of ω-NG-monomethylarginine and asymmetric ω-NG,NG-dimethylarginine on both histone and non-histone targets. Non-histone targets of…

Human Mitochondrial Transcription Factor B2 (h-mtTFB2) is a 42 kDa, single-subunit protein resident in human mitochondria that is needed for in vivo mitochondrial transcription. h-mtTFB2 can stimulate promoter specific mtDNA transcription in an in vitro assay system comprising purified…

Human Mitochondrial Transcription Factor A (h-mtTFA) is a 25 kDa, single-subunit protein resident in human mitochondria. It is a HMG-box DNA-binding protein that is essential for initiation of mitochondrial transcription from both the human mitochondrial light-strand promoter (LSP) and heavy strand…

Active enzyme for drug discovery research.

Source: Recombinant human N-terminal GST-tagged protein expressed in E. coli amino acids 1,717-1,972 (N- and C-terminal truncation)

Source: Active recombinant N-terminal His-tagged protein expressed in E. coli Mr: 44.6 kDa

Source: Recombinant N-terminal His-tagged protein expressed in Sf21 cells Mr: 53.5 kDa EED is a WD40 repeat-containing protein that forms part of the Polycomb repressive complex 2 (PRC2). The EED subunit does not contain methyltransferase activity. However, transcriptional repression by…