Cayman Chemical

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Cayman Chemical

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  • Vitellogenin (killifish) Monoclonal Antibody (ND-5F8)

    Cayman Chemical

    Antigen: Vtg purified from plasma of 17β-estradiol treated killifish (F. heteroclitus), white perch (M. americans), bowfin (A. calva), and egg yolk from swordfish (X. gladius) Host: mouse Cross-reactivity: (+) killifish (F. heteroclitus), white perch (M. americans), common carp (C.…

  • Leukotriene B4-3-aminopropylamide

    Cayman Chemical

    An analog of LTB4 that binds to the BLT1 and BLT2 receptors with Ki values of 5.1 and 1,227 nM, respectively.

  • UltraPure Water

    Cayman Chemical

    Water used for the preparation of EIA reagents and buffers.

  • Biliverdin (hydrochloride)

    Cayman Chemical

    A green bile pigment produced from the oxidation of heme in a reaction catalyzed by heme oxygenase and further reduced to bilirubin by biliverdin reductase; possesses anti-mutagenic and antioxidant properties, scavenging free radicals.

  • Prostaglandin I2 (sodium salt)

    Cayman Chemical

    PGI2 is an unstable COX metabolite detected first in vascular endothelial cells. It elevates platelet cAMP and is a potent vasodilator and inhibitor of human platelet aggregation with an IC50 value of 5 nM. PGI2 is stable in basic buffers (pH=8), but it is rapidly hydrolyzed to 6-keto…

  • DAPI (hydrochloride)

    Cayman Chemical

    A fluorescent probe which is commonly used to stain DNA and chromosomes for fluorescent microscopy and flow cytometry applications; characterized by ultraviolet (max 358 nm) excitation and blue (max 461 nm) emission wavelengths.

  • Pentylenetetrazole

    Cayman Chemical

    A central nervous system modulator that is used to experimentally induce seizures in animals; used extensively to screen for compounds that block the production of nonconvulsive (absence or myoclonic) seizures.

  • AS-1892802

    Cayman Chemical

    Formal Name: N-[(1S)-2-hydroxy-1-phenylethyl]-N'-[4-(4-pyridinyl)phenyl]-urea CAS Number: 928320-12-1 Molecular Formula: C20H19N3O2

  • Catalase Assay Kit

    Cayman Chemical

    Catalase is an ubiquitous antioxidant enzyme that is present in most aerobic cells. It is involved in the detoxification of H2O2, a ROS that is a toxic product of both normal aerobic metabolism and pathogenic ROS production. Cayman’s Catalase Assay utilizes the peroxidatic function of…

  • Pterostilbene

    Cayman Chemical

    A naturally-occurring dimethyl ether analog of resveratrol; acts as a powerful antioxidant, suppresses the synthesis of PGE2 from LPS-stimulated human peripheral blood mononuclear cells (IC50 = 1.0 μM), and inhibits cell proliferation (IC50 = ~60 μM); evokes effects that…

  • JC-1 Mitochondrial Membrane Potential Assay Kit

    Cayman Chemical

    Mitochondrial membrane potential, Δψm, is an important parameter of mitochondrial function that is used as an indicator of cell health. JC-1 is a lipophilic, cationic dye that can selectively enter into mitochondria and reversibly change color from green to red as the membrane potential…

  • Syk Inhibitor II (hydrochloride)

    Cayman Chemical

    A cell-permeable, selective, and reversible inhibitor of Syk (IC50 = 41 nM); prevents FcεRI-mediated 5-HT release in RBL-2H3 cells in vitro (IC50 = 460 nM) and inhibits passive cutaneous anaphylaxis reactions in mice (ID50 = 13.2 mg/kg, s.c.).

  • GSK5959

    Cayman Chemical

    A potent, selective, and cell-permeable inhibitor of the BRPF1 bromodomain (IC50 = 80 nM); disrupts chromatin binding of BRPF1 in a cellular assay by blocking the interaction of BRPF1 with histone H3.3.

  • Ricinoleic Acid

    Cayman Chemical

    Ricinoleic acid is a naturally occurring 12-hydroxy fatty acid. It constitutes about 90% of the fatty acids in castor oil. Ricinoleic acid can serve as a substrate for the synthesis of conjugated linoleic acids. It is considered safe and non-toxic as a food constituent in humans, up to a daily…

  • Ibuprofen

    Cayman Chemical

    A non-selective, reversible COX inhibitor. with IC50 values for human recombinant COX-1 and -2 at 2.6 and 1.53 µM, respectively; Ki values for ovine COX-1 and -2 are both 9 µM.

  • Superoxide Dismutase Assay Kit

    Cayman Chemical

    Cayman’s SOD Assay is a fast and reliable assay for the measurement of SOD activity from plasma, serum, tissue homogenates, and cell lysates. SOD activity is assessed by measuring the dismutation of superoxide radicals generated by xanthine oxidase and hypoxanthine in a convenient 96-well…

  • REV 5901

    Cayman Chemical

    REV 5901 is an antagonist of cysteinyl-leukotriene receptors with a Ki value of 0.7 µM for guinea pig lung membranes. It is also an inhibitor of rat neutrophil 5-LO with an IC50 value of 0.12 µM.

  • Hepsin Blocking Peptide (aa 241-260)

    Cayman Chemical

    Peptide Sequence: human hepsin amino acids 241-260 (GGYLPFRDPNSEENSNDIAL) To be used in conjunction with Cayman’s hepsin polyclonal antibody - affinity-purified (Catalog No. 100022) to block protein-antibody complex formation during analysis for hepsin.

  • Aflatoxin B2

    Cayman Chemical

    The dihydro derivative of Aflatoxin B1.

  • p53 Transcription Factor Assay Kit

    Cayman Chemical

    The tumor suppressor protein p53 plays a crucial role in coordinating cellular responses to genotoxic stress and holds many important clinical implications in the treatment of cancer. Cayman’s p53 Transcription Factor Assay is a non-radioactive, sensitive method for detecting specific…

  • TBARS Assay Kit

    Cayman Chemical

    Oxidative stress in the cellular environment results in the formation of highly reactive and unstable lipid hydroperoxides. Decomposition of the unstable peroxides derived from polyunsaturated fatty acids results in the formation of malondialdehyde (MDA), which can be quantified colorimetrically…

  • Sclerotiorin

    Cayman Chemical

    A natural product that inhibits soybean LO-1 (IC50 = 4.2 µM), cholesterol ester transfer protein (IC50 = 19.4 µM), Grb2-Shc interaction (IC50 = 22 µM), and antagonizes endothelin receptors (IC50 = 114 and 152 µM for human ETA and…

  • HAMI3379

    Cayman Chemical

    A potent, selective CysLT2 receptor antagonist that inhibits radioligand binding of LTD4 to CysLT2 and CysLT1 receptor cell lines with IC50 values of 37.9 and >10, 000 nM, respectively.

  • tetranor-PGDM-d6

    Cayman Chemical

    An internal standard for the quantification of tetranor-PGDM by GC- or LC-MS.

  • DNA Methylation ELISA Kit

    Cayman Chemical

    DNA methylation is an important epigenetic process regulating gene expression. Methylation occurs on carbon 5 of 2-deoxy cytidine yielding the modified base 5-methyl-2-deoxy cytidine. The methylation pattern of cells is tightly regulated during development with the methylation profile being…

  • Echinomycin

    Cayman Chemical

    A cell-permeable inhibitor of HIF-1-mediated gene transcription which acts by intercalating into DNA in a sequence-specific manner, blocking the binding of either HIF-1α or HIF-1β to the HRE; reversibly inhibits hypoxia-induced HIF-1 transcription activity in U215 cells with an EC50…

  • 10-POHSA

    Cayman Chemical

    A FAHFA in which palmitoleic acid is esterified to 10-hydroxy stearic acid.

  • Triphenylphosphine oxide

    Cayman Chemical

    A coordinating solvent used to activate crystallization of chemical compounds; used in flame retardant applications, as an epoxy cure catalyst, and to produce nanostructures.

  • ERa (human) Reporter Assay Kit

    Cayman Chemical

    This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the full-length human estrogen receptor 1 (NR3A1), a ligand-dependent transcription factor commonly referred to as ERα. INDIGO’s reporter cells include…

  • Sulforaphane

    Cayman Chemical

    An isothiocyanate that potently induces chemopreventative enzymes via Keap1-Nrf2 signaling and ARE-driven gene expression; at 15 μM, inhibits class I and II HDAC activity and suppresses tumor growth selectively in cancerous prostate epithelial cells without affecting normal cells.

  • Auraptene

    Cayman Chemical

    A coumarin derived from citrus plants with anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities; inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis.

  • AL 8810 isopropyl ester

    Cayman Chemical

    A lipid soluble, esterified prodrug of AL 8810.

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