Source: Active recombinant N-terminal His-tagged protein expressed in Sf21 cells Mr: 43.7 kDa PRMT6 is a nuclear type-1 PRMT, catalyzing the formation of ω-NG-monomethylarginine and asymmetric ω-NG,NG-dimethylarginine on both histone and non-histone targets. Non-histone targets of…

Active recombinant N-terminal GST-tagged protein expressed in E. coli • G9a-like protein (GLP) is a SET domain-containing methyltransferases that specifically mono- and di-methylate histone H3 at lysine 9 (H3K9).

A cytotoxin that inactivates host Rho family GTPases by glucosylation, altering cytoskeletal structure, cell division, and cell-cell adhesion.

Source: Recombinant human N-terminal GST-tagged protein expressed in E. coli amino acids 1,717-1,972 (N- and C-terminal truncation)

Source: recombinant protein expressed in Sf21 cells Mr: 54 kDa PPARs are members of the nuclear receptor family of ligand activated transcription factors that heterodimerize with retinoic acid like receptors, regulating gene expression and differentiation. PPARδ is a mediator of diverse…

Source: Recombinant protein expressed in E. coli MW: 12.5 kDa

Source: Recombinant N-terminal His-tagged protein expressed in Sf21 cells Mr: 53.5 kDa EED is a WD40 repeat-containing protein that forms part of the Polycomb repressive complex 2 (PRC2). The EED subunit does not contain methyltransferase activity. However, transcriptional repression by…

Source: Active human recombinant C-terminal His-tagged protein preceded by a linker region and V5 epitope expressed in E. coli Mr: 34 kDa

Recombinant protein expressed in E. coli DPY-30 is a component of the MLL1 methylation complex, which interacts directly with Ash2L.

Protein Arginine Deiminases (PADs) are guanidino-modifying enzymes belonging to the amidinotransferase superfamily and are designated PAD1-4 and PAD6. PAD enzymes catalyze the conversion of specific arginine residues to citrulline in a calcium-dependent manner. All enzymes are cytosolic except for…

Source: Recombinant N-terminal His- and SUMOpro-tagged protein expressed in E. coli Mr: 34.5 kDa

Source: Active recombinant C-terminal His-tag expressed in E. coli MW: 45.3 kDa HDAC8 is a Class I HDAC that catalyzes the deacetylation of core histones, resulting in tightening of nucleosomal integrity, restricting access to transcription factors, and suppression of transcription. It can…

Source: Recombinant protein expressed in E. coli RbBP5 is a ubiquitously expressed nuclear protein that contains WD40 repeat-like domains. RbBP5 binds directly to tumor suppressor retinoblastoma protein (RB) and regulates cell proliferation. RbBP5 is also an important component of the…

Source: human recombinant N-terminal His-tagged protein expressed in E. coli Mr: ~60 kDa PPARs are members of the nuclear receptor family of ligand activated transcription factors that heterodimerize with retinoic acid like receptors, regulating gene expression and differentiation.…

Source: recombinant N-terminal GST-tagged protein purified from E. coli Mr: ~45.2 kDa (18.9 kDa native; 26.3 kDa GST-tagged) PtdIns-(4,5)-P2 Binding Protein contains a highly specific PH domain that recognizes and binds PtdIns-(4,5)-P2. PtdIns-(4,5)-P2 can be phosphorylated by…

Source: Recombinant N-terminal His-tagged protein expressed in E. coli MW: 40.48 kDa Annexin A1 is an endogenous mediator of inflammation, promoting resolution in a number of ways. Normally expressed in intracellular compartments, it is drawn to the cell membrane and both induced and…

A toxin that activates GPVI on platelets and initiates blood clotting.

Source: Active mouse recombinant N-terminal His-tagged protein purified from Sf21 cells Mr: 64 kDa sEH catalyzes the hydrolysis of exogenous and endogenous epoxides to vicinal diols. Endogenous substrates for sEH include epoxyeicosatrienoic acids (EETs) which are known for their vasodialatory…

Source: Active human recombinant N-terminal His-tagged protein purified from Sf21 cells Mr: 50.8 kDa PTEN functions as a key regulatory enzyme in many signal transduction pathways by dephosphorylating proteins and lipids such as Akt and PIP3. Mutation of PTEN results in many human cancers…

Source: Active human recombinant N-term His-tagged protein expressed in E. coli Mr: 24.3 kDa One unit of enzyme produces one µmole of PGD2/min at 25°C in 100 mM Tris-HCl buffer, pH 8.0, containing 1 mM GSH, 1 mg/ml magnesium chloride, and 40 µM PGH2

Source: 50 µg of recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 39 kDa NcoR2 is a transcriptional corepressor that plays an essential role in the regulation of development and metabolism. HDACs can mediate nuclear receptor functions by forming co-repressor complexes…

Source: Active human recombinant N-terminal His-tagged protein purified from Sf21 cells Mr: 64 kDa sEH catalyzes the hydrolysis of exogenous and endogenous epoxides to vicinal diols. Endogenous substrates for sEH include epoxyeicosatrienoic acids (EETs) which are known for their vasodialatory…

Source: Active recombinant N-terminal His-tagged enzyme isolated from a HEK293 overexpression system MW: 71 kDa (~16 & 63 kDa purified) PCSK9 is a member of the subtilisin serine protease family with an important role in lipoprotein metabolism. Mutation in the PCSK9 gene is associated…

Recombinant protein expressed in E. coli with a SUMO tag ASH2L is a component of various multisubunit protein complexes, including the large complex of proteins associated with the SET1 (MLL) family of lysine methyltransferases.

Source: recombinant N-terminal GST-tagged protein purified from E. coli Mr: ~41.7 kDa (15.4 kDa native; 26.3 kDa GST-tagged) PtdIns-(3,4,5)-P3 Binding Protein contains a highly specific PH domain that recognizes and binds PtdIns-(3,4,5)-P3. PtdIns phosphates play a critical role in the…