Source: recombinant C-terminal histidine-tagged protein expressed using a baculovirus overexpression system in Sf21 cells
Mr: 98.8 kDa
A secreted lysophospholipase D that catalyzes the hydrolysis of LPC to generate LPA; ATX-LPA signaling is involved in a range of pathologies including tumor progession and inflammation; it is proteolytically processed by cleavage of a 35 amino acid signal peptide and then secreted as a mature protein.