50 mg
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Anti-CHICKEN IgG F(ab')2 (RABBIT) Antibody, 50mg, Lyophilized
Rockland Immunochemicals IncAnti-Chicken IgG antibody is suitable for ELISA, western blot, and immunohistochemistry, as well as other assays requiring lot-to-lot consistency.
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D-AP5
Cayman ChemicalA selective NMDA receptor antagonist (Kd = 1.4 μM) that competitively inhibits the glutamate binding site of NMDA receptors; widely used to study the activity of NMDA receptors particularly in regard to researching synaptic plasticity, learning, and memory.
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CAY10512
Cayman ChemicalCAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activation of NF-κB by CAY10512 is 0.15 µM compared to 20 µM by resveratrol.
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DL-a-Difluoromethylornithine (hydrochloride hydrate)
Cayman ChemicalAn irreversible inhibitor of ornithine decarboxylase that suppresses polyamine biosynthesis; displays antiangiogenic, cytostatic, and antiparasitic effects.
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Arachidonic Acid
Cayman ChemicalKeystone essential fatty acid that is converted by COX, LO, and epoxygenase enzymes into more than 150 potent metabolites in species ranging from fungi to plants to mammals.
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Pomalidomide-PEG6-Alkyne
MilliporeSigmaSynonyms: N-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-4,7,10,13,16,19-hexaoxadocos-21-ynamide; Crosslinker-E3 Ligase ligand conjugate; Protein degrader building block for PROTAC(R) research; Template for synthesis of targeted protein degrader Molecular Formula: C29H37N3O11 …
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L-Mimosine
Cayman ChemicalA non-protein amino acid that chelates iron and copper; inhibits certain enzymes that contain iron or copper, including arginase (IC50 = 3.7 µM).
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Trametinib
Cayman ChemicalA potent inhibitor of both MEK 1 and 2 that works in an ATP-noncompetitive fashion (IC50s = 0.7 and 0.9 nM, respectively); blocks dual phosphorylation of ERK1/2 and stops cell cycling in cancer cell lines, both in vitro and in multiple tumor models in mice.
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Leflunomide
Cayman ChemicalA prodrug for A-771726 that regulates T lymphocyte progression through the cell cycle by selectively inhibiting de novo pyrimidine synthesis; used to slow the disease progression of rheumatoid arthritis and as an immunosuppressive agent to prevent rejection of transplant allografts and xenografts.
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SB-258585 (hydrochloride)
Cayman ChemicalA potent, selective antagonist of the serotonin 5-HT6 receptor (pKi = 8.53); has been used in cells and in animals.
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ADT-OH
Cayman ChemicalA synthetic H2S donor that can be readily esterified with other moieties, including therapeutics and targeting motifs; used both in cells and in animals for comparative studies with derived chimeras.
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Hydroxy Linoleins
Cayman ChemicalHydroxy linoleins are a mixture of 132 possible isomers of mono-, di-, and tri-hydroxy compounds produced by the autoxidation of trilinolein and subsequent reduction of the hydroperoxides. Autoxidation of linoleic acid containing triglycerides (i.e., trilinolein) in vivo could result in the…
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Bosutinib
Cayman ChemicalBest known as a potent dual inhibitor of c-Src and Abl (IC50 = 1.2 and 1.0 nM, respectively); can be effective in regulating tumor growth and differentiation; also inhibits other members of the Src and TEC families and certain other kinases at nanomolar concentrations.
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Fludarabine
Cayman ChemicalA nuclesoside analog that disrupts DNA synthesis in blood cells; effective in a number of animal tumor systems including LI210 leukemia, CD8F mammary adenocarcinoma, P388 leukemia, and human LX-1 lung tumor xenograft and displays anticancer activity against human hematological malignancies in vivo.
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XTT (sodium salt)
Cayman ChemicalA cell-impermeable, negatively charged tetrazolium dye that produces a water-soluble formazan when reduced at the cell surface by cellular-derived NADH and an electron mediator.
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Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards Synonyms: 10-Deacetyl-7-epipaclitaxel; 7-epi-10-Deacetyltaxol Molecular…
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Fluorescein isothiocyanate, isomer 1, 95%
Thermo Scientific ChemicalsFormula: C21H11NO5S Formula weight: 389.39 Purity: 95% CAS Number: 3326-32-7 Harmonized Tariff Code: 2932.20 Hazard Statements: H334-H317 May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction. Precautionary Statements: …
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TAK-632
Cayman ChemicalA selective slow off-rate inhibitor of Raf kinases (IC50s = 8.3, 2.4, and 1.4 nM for wild type B-Raf, mutant B-RafV600E, and c-Raf, respectively); shows significant antiproliferative activity against mutated BRAF or mutated NRAS cancer cell lines and xenograft models.
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NO-Indomethacin
Cayman ChemicalA hybrid molecule of indomethacin and an NO donor which combines the anti-inflammatory properties of an NSAID with the gastrointestinal protective effects of NO.
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ALDRICH 2-cis,4-trans-Abscisic acid, synthetic, 98%
MilliporeSigmaSynonym(s): (±)-Abscisic acid; (2 Z ,4 E )-5-(1-Hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl)-3-methyl-2,4-pentadienoic acid; ABA; Dormin Formula: C15H20O4 Formula Weight: 264.32 CAS No.: 14375-45-2 Purity: 98% Storage: 2-8°C …
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Colcemid
Cayman ChemicalA colchicine derivative that inhibits tubulin polymerization (IC50 = 2.1 μM) with low toxicity; suppresses microtubule dynamicity, inhibits cell migration, blocks microtubule assembly, and arrests cells in metaphase; used to synchronize cells and for karyotyping in cytogenetic studies.
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7-Methylxanthine, 98%
Thermo Scientific ChemicalsSynonym(s): 2,6-Dihydroxy-7-methylpurine, Heteroxanthine Formula: C6H6N4O2 Formula weight: 166.14 Purity: 98% CAS Number: 552-62-5 Harmonized Tariff Code: 2933.59
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"Quizalofop-ethyl, PESTANAL®, analytical standard"
MilliporeSigmaSynonyms: Ethyl 2-[4-(6-chloro-2-quinoxalinyloxy)phenoxy]propionate Formula: C19H17ClN2O4 Formula Weight: 372.80 CAS No.: 76578-14-8 Legal Information: PESTANAL is a registered trademark of Sigma-Aldrich Laborchemikalien GmbH
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N^a-(p-Toluenesulfonyl)-DL-lysine chloromethyl ketone hydrochloride, 98%
Thermo Scientific ChemicalsSynonym(s): TLCK, N^a-p-Tosyl-DL-lysine chloromethyl ketone hydrochloride Formula: C14H21ClN2O3S HCl Formula weight: 369.31 Purity: 98% CAS Number: 4238-41-9 Harmonized Tariff Code: 2935.00 Hazard Statements: H315-H319-H335 Causes skin irritation. Causes serious eye irritation.…
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Omeprazole sulfone
Cayman ChemicalThe major metabolite of the gastric proton pump inhibitor, omeprazole; produced by CYP3A4 sulfoxidation of esomeprazole.
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SIGMA Pepstatin A >=100,000 U/mg
MilliporeSigmaEmpirical Formula: C34H63N5O9 Linear Formula: C34H63N5O9 Formula Weight: 685.89 MDL Number: MFCD00060740 Melting Point: 233 °C (dec.)(lit.) Storage: 2-8°C Beilstein Registry…
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11-Maleimidoundecanoic acid sulfo-NHS ; 99%
AFG BioscienceSynonyms: Sulfo-KMUS Purity Limit: 99% CAS No.: 211236-68-9 Molecular Formula: C19H25N2O9SNa Molecular Weight: 485.47 MDL No.: MFCD01075057 Melting Point: 245 °C (Decomp) Storage Temperature: Store at 0-8°C
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Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards Synonyms: Pantoprazole sulfone;…
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KC7F2
Cayman ChemicalAn inhibitor of HIF-1α protein translation; suppresses phosphorylation of two key regulators of protein synthesis, eukaryotic translation initiation factor 4E binding protein 1 (4EBP1) and p70 S6 kinase; cytotoxic to a variety of cancer cell lines with an IC50 value of 15-25 µM.
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Dalcetrapib
Cayman ChemicalAn inhibitor of CETP; inhibits plasma CETP with an IC50 value of 9 µM; in rabbits given an atherogenic diet, increases HDL, decreases VLDL, and attenuates induced atherosclerosis; in humans, inhibits CETP activity and increases HDL levels but does not reduce the risk of recurrent…