Purity Limit: ≥ 99% (NMR) Molecular Formula: C11H17N3O6 Molecular Weight: 287.27 MDL No.: MFCD09952649 Appearance: White to off-white solid Melting Point: 145-146 °C (dec.) Storage Temperature: Store at ≤ -4 °C

Poly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein. It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When…

β-NADP is a coenzyme necessary for the alcoholic fermentation of glucose and the oxidative dehydrogenation of other substances. It occurs widely in living tissue, especially in the liver. Nicotinic acid can be converted to nicotinamide in the body and, in this form, is found as a component of…

Anti-Guinea Pig IgG F(ab')2 antibody is suitable for ELISA, western blot, and immunohistochemistry, as well as other assays requiring lot-to-lot consistency.

Anti-Goat IgG IgM antibody is suitable for ELISA, western blot, and immunohistochemistry, as well as other assays requiring lot-to-lot consistency.

Epoxyeicosatrienoic acid (EpETrE; EET) metabolites of arachidonic acid such as 11(12)-EET and 14(15)-EET have been identified as endothelium derived hyperpolarizing factors with vasodilator activity. Soluble epoxide hydrolase (sEH) catalyzes the conversion of EETs to the corresponding dihydroxy…

Synonyms: 2-(((2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl)sulfanyl)benzoic acid; FTS; Farnesylthiosalicylic acid; S-Farnesylthiosalicylic acid Molecular Formula: C22H30O2S Molecular Weight: 358.54 Linear Structural Formula: C22H30O2S MDL Number: MFCD00467723 Purity: >=98%…

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards Synonyms: 1,2-Dimethyl-1,4,5,6-tetrahydropyrimidine Molecular Formula: …

A potent, cell-permeable inhibitor of all JAK isoforms (IC50 = 6.1, 12, and 8.0 nM for JAK1, JAK2, and JAK3, respectively); useful in ameliorating inflammatory or autoimmune components of a host of diseases.

An antifungal agent that acts as an inverse agonist to disrupt Hh signaling (IC₅₀ = 0.8 μM); treatment at 100 mg/kg twice per day has been shown to suppress the growth of medulloblastomas from a Ptch+/-p53-/- mouse allograft model.

Synonym(s): 1-[2-[(Methylsulfonyl)-amino]ethyl]-4-piperidinyl]methyl 1-methyl-1H-indole-3-carboxylate Empirical Formula: C₁₉H₂₇N₃O₄S Linear Formula: C₁₉H₂₇N₃O₄S Formula Weight: 393.50 MDL Number: …

A natural alkaloid with antiviral properties, inhibiting the replication of hepatitis B alone and in combination with lamivudine; prevents fibrosis in a number of organs including liver, at least in part by interfering with TGF-β signaling.

Synonyms: o -XBDiBDTC; o -Xylylenebis( N , N -diisobutyldithiocarbamate) Formula: C₂₆H₄₄N₂S₄ Formula Weight: 512.90 CAS No.: 125769-67-7 General description: Visit our Sensor Applications portal to learn more. Other Notes: Neutral…

Synonym(s): L-Deoxyalliin; S-allyl-cysteine; S-allylcysteine; SAC Empirical Formula: C₆H₁₁NO₂S Linear Formula: C₆H₁₁NO₂S Formula Weight: 161.22 MDL Number: MFCD00151975 Purity: ≥98% (HPLC) Storage: 2-8°C

Empirical Formula: C₅H₉NO₂ Linear Formula: C₅H₉NO₂ Formula Weight: 115.13 MDL Number: MFCD00166364 Storage: −20°C

Synonyms: 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide; Crosslinker-E3 Ligase ligand conjugate; Protein degrader building block for PROTAC(R) research; Template for synthesis of targeted protein degrader Molecular Formula: C21H24N6O8 …

GSK2126458 is a potent inhibitor of phosphoinositide 3-kinase isoforms (K_is = 19, 130, 24, and 60 pM for p110α, β, δ, and γ, respectively). It also inhibits mTOR in both mTORC1 and mTORC2 (K_is = 180 and 300 nM, respectively), as well as several common…

A selective inhibitor of PFKFB3 (IC₅₀ = 207 nM); rapidly induces apoptosis in transformed cells, suppresses glucose uptake and growth of Lewis lung carcinomas in syngeneic mice, and yields antitumor effects in human xenograft models of cancer in athymic mice.

8-hydroxy Guanine is produced by oxidative damage of DNA or RNA by reactive oxygen and nitrogen species, including hydroxyl radical and peroxynitrite. It serves as a measure of oxidative stress in biological systems.

An inhibitor of HIF-1α protein translation; suppresses phosphorylation of two key regulators of protein synthesis, eukaryotic translation initiation factor 4E binding protein 1 (4EBP1) and p70 S6 kinase; cytotoxic to a variety of cancer cell lines with an IC₅₀ value of 15-25 µM.

An irreversible, noncompetitive inhibitor of PARP1 that disrupts binding between PARP1 and DNA by interacting with the DNA binding domain; produces rapid apoptosis in the various cancer cell (IC50s = 40-128 μM).

Synonym(s): H-Tyr-Gly-Gly-Phe-Met-OH Formula: C27H35N5O7S Formula weight: 573.67 CAS Number: 58569-55-4 Harmonized Tariff Code:  2930.90

Synonym(s): CNQX, 6-Cyano-7-nitroquinoxaline-2,3(1H,4H)-dione Formula: C9H4N4O4 Formula weight: 232.16 Purity: 99+% CAS Number: 115066-14-3 Harmonized Tariff Code:  2933.59 Hazard Statements: H301-H315-H319-H335 Toxic if swallowed. Causes skin irritation. Causes serious eye…

Formula: C₂₅₄H₃₇₇N₆₅O₇₅S₆ Formula Weight: 5733.49 CAS No.: 11070-73-8 Application: Insulin is used as a growth factor in many mammalian cell culture systems. Physical form: powder-0 °C; solution stable 2-8 °C, 1 year …

A cell-permeable compound that maintains long-term mouse ESC pluripotency; allows ESCs to form embryoid bodies that continue to express markers of pluripotency when used at 4 µg/ml with Wnt3a; blocks the interaction of Nkd with a subunit of PP2A.

A natural polymethoxylated flavonoid and potent antioxidant with good bioavailability; has anti-inflammatory effects that are relevant to a host of diseases, including cancer, arthritis, and neurodegeneration; inhibits P-glycoprotein and BCRP (IC₅₀ = 11.5 and 4.9 μM, respectively).

Synonym(s): Siderophilin; Siderophilin, iron-saturated MDL Number: MFCD00131337 Purity: ~98% Storage: 2-8°C

Synonyms: Sulfo-KMUS Purity Limit: 99% CAS No.: 211236-68-9 Molecular Formula: C19H25N2O9SNa Molecular Weight: 485.47 MDL No.: MFCD01075057 Melting Point: 245 °C (Decomp) Storage Temperature: Store at 0-8°C

Anti-Human IgG antibody is suitable for immunoblotting (western or dot blot), ELISA, immunoelectron microscopy and immunohistochemistry as well as other antibody based enzymatic assays requiring lot-to-lot consistency.

A metabolite of dimetridazole, the nitroimidazole-based antibacterial and anticoccidial agent suspected to be carcinogenic and mutagenic to humans.

Synonyms: N -(3-Oxohexanoyl)-DL-homoserine lactone Formula: C₁₀H₁₅NO₄ Formula Weight: 213.23 CAS No.: 76924-95-3 Storage Temperature: −20°C