50 mg, 103628-48-4

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  • Cayman Chemical

    A serotonin 5-HT1B and 5-HT1D receptor agonist (IC50s = 9.3 and 7.3 nM, respectively) that also has affinity for the 5-HT1F receptor (IC50 = 17.8 nM); constricts human middle meningeal arteries (EC50 = 89.9 nM) and reduces vascular inflammation associated with migraines.