MP Biomedicals, 1 g
MP Biomedicals
MP Biomedicals is a worldwide corporation manufacturing and distributing systems, kits and reagents for the life science research, medical device, biopharma manufacturing and diagnostics markets. Our extensive portfolio and custom services deliver the dependability that research and industrial communities rely on to worry less and discover more. From small scale research to large scale manufacturing, MP Biomedicals has been advancing life science projects for over 50 years.
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Papain from Papaya Latex
MP BiomedicalsPapain is a sulfhydryl protease from Carica papaya latex. Cleaves peptide bonds of basic amino acids, leucine, or glycine Hydrolyzes esters and amides One unit will hydrolyze 1.0 µmole of N-alpha-benzoyl-L-arginine ethyl ester (BAEE) per minute at 25°C and pH 6.2 Papain…
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NZ Bovine Transferrin (Holo), Heat Treated, 1 g
MP BiomedicalsBovine Transferrin is chromatographically purified from New Zealand-sourced bovine plasma in an ISO quality system assuring complete traceability and consistent high quality. Transferrin (HOLO) is an iron-rich product supplied as a heat-treated, lyophilized powder.
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Pectolyase Y-23 (A. niger)
MP BiomedicalsPectolyase Y-23 is a highly purified maceration enzyme from Aspergillus niger. It contains two types of pectinase such as endopolygalacturonase and endo-pectin lyase in high activity. Included is a maceration stimulating factor which stimulates tissue maceration by both pectinases. Unit Definition:…
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Human Gamma Globulins, Fraction II
MP BiomedicalsEach donor unit used in the preparation of the product was tested and found negative for Anti-HIV 1/2, HBsAg, Anti-HCV and HIV-1 Ag by FDA approved methods or CE approved methods. Used as an immunological challenge in studies of mechanisms of immunotolerance.
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Colistin Sulphate Salt
MP BiomedicalsColistin is a polymyxin antibiotic, it is a mixture of cyclic polypeptides colistin A and B. Colistin is effective against most Gram-negative bacilli and is used as a polypeptide antibiotic. Colistin sulfate is used to permeabilize bacterial cell membranes and to study mannose-resistant…
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3,3-Diaminobenzidine Tetrahydrochloride
MP Biomedicals3,3-Diaminobenzidine Tetrahydrochloride is a reagent used in colorimetric analysis of Se and other metals. DAB is utilized in many applications for visualization of peroxidase activity. In the peroxidase reaction DAB serves as a hydrogen donor in the presence of peroxide; the oxidized DAB forms…
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G418 Sulfate
MP BiomedicalsProduct Description Antibiotic. Cytotoxic to prokaryotic and eukaryotic cells by inhibiting the protein synthesis. Apoptosis inducer. Widely employed in the selection of eukaryotic expression vectors, in combination with either aminoglycoside phosphotransferase 3' or APH II. Antiviral. …
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Guanosine-5'-Triphosphate Disodium Salt
MP BiomedicalsGuanosine-5'-triphosphate, a purine nucleotide, is required as a coenzyme for protein biosynthesis in a cell-free system. Guanosine 5′-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR)…
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Fetuin from Fetal Bovine Serum
MP BiomedicalsFetuin is a protein containing 12 Cys residues, all involved in disulfide bridges. The composition of bovine fetuin (weight %) is polypeptide 74%, hexose 8.3%, hexosamines 5.5%, and sialic acid 8.7%. Fetuin bovine is a protein with the ability to bind to the insulin receptor and inhibit insulin…
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Proteinase K, Recombinant, Reagent Grade, Lyophilized Powder
MP BiomedicalsProteinase K Lyophilized Powder, ≥ 30 U/mg, Recombinant (Yeast). Proteinase K, a broad-spectrum serine protease, is first extracted and purified from Engyodontium album. It is named Proteinase K because it can degrade Keratin. The crystallization and molecular structure of…
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Spectinomycin is an aminocyclitol antibiotic, closely related to the aminoglycosides, it inhibits protein synthesis (elongation) by interfering with peptidyl tRNA translocation. Mutation in rpsE (the gene for ribosomal protein S5) prevents binding of spectinomycin. Specinomycin is used in cell…
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Tamoxifen
MP BiomedicalsTamoxifen is a Protein Kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in…
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ß-Nicotinamide Adenine Dinucleotide
MP Biomedicalsβ-NAD is one of the biologically active forms of nicotinic acid. Occurs in living cells, primarily in the oxidized state Coenzyme for dehydrogenases NAD usually acts as a hydrogen acceptor, forming NADH Major electron acceptor molecule in biological oxidations. Acts as a…
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D-Penicillamine
MP BiomedicalsPhysiological chelating agent for heavy metals. It is used as an antirheumatic and as a chelating agent in Wilson′s disease. It is used as a copper chelator to form mixed disulfides with cysteine or other sulfide media components. It is used to inactivate protein-1 DNA binding and to…
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Chloroplatinic Acid Hexahydrate
MP BiomedicalsChloroplatinic acid hexahydrate is an analytical reagent. Chloroplatinic acid is used in potassium determination, purification of platinum and in catalysis.
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Human Albumin, Crystallized (1X Cohn Crystallized)
MP BiomedicalsPrepared using Cohn method IV. The material is non-reactive for HbsAg, Anti-HCV 3.0, Anti-HIV-1/2 and STS (RPR). This material is also negative for HIV-1 and HCV by PCR ALBUMIN, HUMAN is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research;…
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Calcein
MP BiomedicalsCalcein is used as an indicator for the determination of calcium by titration with EDTA. Suitable for fluorometric determination of calcium. Calcein does not fluoresce in strong alkaline solution, but an intense fluorescence appears in the presence of alkaline earths, especially calcium. The…
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Dextran Sulfate Sodium Salt, Colitis Grade
MP BiomedicalsDextran sulfate sodium salt, or DSS, is a synthetic sulfated branched polysaccharide derivative of dextran that has multiple uses in biomedical and clinical research. One important property of DSS is to trigger colitis in mice and rats when administered in drinking water. DSS binds to…
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Adenosine-5'-Diphosphate Monopotassium Salt Dihydrate
MP BiomedicalsAdenosine 5′-diphosphate is a P2Y receptor agonist. Adenosine 5′-diphosphate has been used to study the release, neuronal effects and removal of extracellular β-nicotinamide adenine dinucleotide (β-NAD+) in the rat brain. Adenosine 5′-diphosphate has also been used to…
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G418 Disulfate, Phytopure™
MP BiomedicalsG418 is an aminoglycoside related to Gentamicin and is toxic to bacteria, yeast, higher plants, mammalian cells, protozoans and helminths. It blocks polypeptide synthesis in both prokaryotic and eukaryotic cells and is useful for selection of genetically engineered eukarytoic cells in culture.
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Doxycycline Hydrochloride
MP BiomedicalsDoxycycline is an antibiotic against gram-positive and gram-negative bacteria. More active biologically than the corresponding 6b-epimer hydrochloride. Derivative of oxytetracycline. A broad spectrum inhibitor used to inhibit matrix metallo-proteinases (MMP) such as type 1 collagenase in…
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Pectolyase Y-23 from Aspergillus japonicus
MP BiomedicalsPectolyase Y-23 is a highly purified maceration enzyme from Aspergillus japonicus. It contains two types of pectinase such as endopolygalacturonase and endo-pectin lyase in high activity. Included is a maceration stimulating factor which stimulates tissue maceration by both pectinases. Enzyme…
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Heparin Sodium Salt from Porcine
MP BiomedicalsHeparin is a polymer classified as a mucopolysaccharide or a glycosoaminoglycan. It is biosynthesized and stored in mast cells of various mammalian tissues, particularly liver, lung and mucosa. It is made up of repeated disaccharide units consisting of 1,4-linked L-iduronic acid and D-glucosamine.…
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Triolein
MP BiomedicalsTriolein is a symmetrical triglyceride. Triolein is used as a substrate for microbial lipases.
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Melatonin
MP BiomedicalsMelatonin is a hormone of the pineal gland. Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell…
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2,3,5-Triphenyl Tetrazolium Chloride
MP Biomedicals2,3,5-Triphenyltetrazolium Chloride is a redox indicator. In the TTC assay (also known as TTC test or tetrazolium test), TTC is used to differentiate between metabolically active and inactive tissues. The white compound is enzymatically reduced to red TPF (1,3,5-triphenylformazan) in living tissues…
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Collagenase from Clostridium histolyticum
MP BiomedicalsCollagenase products are prepared from culture supernatants of C. histolyticum. It is prepared to contain lower tryptic activity to limit damage to membrane proteins and receptors but with normal to above normal collagenase activity. Suggested for pacreatic islet isolation. Crude Collagenases…
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Isopropyl-ß-D-Thiogalactopyranoside
MP BiomedicalsIPTG (isopropyl-β-thiogalactoside) is an analogue of allolactose that binds specifically to the repressor protein of the lac operon and induces expression of β-galactosidase in Escherichia coli. IPTG is a commonly used reagent in cloning procedures that require induction of…
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Amikacin
MP BiomedicalsAmikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections. Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth. Amikacin must be given by the…
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Albumin from Chicken Egg White
MP BiomedicalsChicken egg albumin is the major protein constituent of egg whites. Chicken egg albumin is a phosphorylated-glycoprotein. From the amino acid sequence, the peptide portion of the molecule consists of 385 residues and has a molecular weight of 42.7 kDa. A phosphorylated glycoprotein which is…
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Adenosine-5'-triphosphate
MP BiomedicalsAdenosine-5'-triphosphate (ATP) disodium salt, >99%. Crystalline.
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Dexamethasone
MP BiomedicalsDexamethasone is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S…