Cayman Chemical, 1 each, Chemicals
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Glutathione S-Transferase Polyclonal Antibody
Cayman ChemicalAntigen: purified glutathione S-transferase (S. japonicum) Host: rabbit Cross-reactivity: (+) GST and GST fusion proteins Application: WB and IP; other applications not tested (not intended for detection of mammalian GST)
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WST-1 Cell Proliferation Assay Kit
Cayman ChemicalCayman’s WST-1 Proliferation Assay is based on the reduction of tetrazolium salt WST-1 to a soluble formazan dye by electron transport across the plasma membrane of dividing cells. This kit will also allow investigators to screen drug candidates involved in cell cycle regulation.
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iNOS Polyclonal Antibody
Cayman ChemicalAntigen: purified enzyme from mouse macrophages (RAW 264.7 cells) Host: rabbit Cross Reactivity: (+) iNOS from most mammalian species and nNOS (~5%); (−) eNOS Application(s): ICC, IP, and WB NOS catalyzes the biosynthesis of nitric oxide from L-arginine. iNOS is a soluble enzyme…
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Primary COX and LOX LC-MS Mixture
Cayman ChemicalFeatures Each vial contains a mixture of standards packaged in amber ampules purged with argon >1 ml provided at the concentration specified in the insert Designed for direct snap and inject use in mass spectrometry applications Ideally suited for method development and as a…
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ß-Catenin Polyclonal Antibody
Cayman ChemicalImmunogen: synthetic peptide from the N-terminal region of human protein Host: rabbit Cross Reactivity: (+) human, mouse, rat, porcine, and bovine β-catenin Application(s): IHC and WB β-Catenin is a multifunctional protein known to be part of the Wnt pathway, playing essential…
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GSK3ß (Phospho-Ser9) Polyclonal Antibody
Cayman ChemicalAntigen: phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser9 of GSK3β Host: rabbit Cross Reactivity: (+) rat GSK3β; expected to react with human, bovine, canine, chicken, mouse, non-human primate, Xenopus, and zebrafish GSK3β Application(s): WB …
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Dopamine ß-hydroxylase (N-Term; human) Polyclonal Antibody
Cayman ChemicalAntigen: Peptide from the N-terminal region of human dopamine β-hydroxylase (DBH) Host: sheep Cross Reactivity: (+) Human and non-human primate tissue DBH Application: WB
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FFAR1 (GPR40) Reporter Assay Kit
Cayman ChemicalFFAR1/GPR40 is a G protein-coupled receptor for long-chain fatty acids such as DHA and EPA ω-3 fatty acids. It is involved in the regulation of insulin release from pancreatic β cells and mediates triglyceride-induced secretion of incretins GLP-1 and GIP from intestinal endocrine cells.…
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ß-Catenin Blocking Peptide
Cayman ChemicalPeptide Sequence: human β-catenin amino acids 43-62 (APSLSGKGNPEEEDVDTSQV) To be used in conjunction with Cayman’s β-catenin polyclonal antibody (Catalog No. 100029) to block protein-antibody complex formation during analysis for β-catenin.
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CD36 Monoclonal Antibody (Clone JC63.1) (azide free)
Cayman ChemicalAntigen: recombinant adenovirus expressing full-length mouse CD36 Host: CD36 null mouse, clone JC63.1 Cross Reactivity: (+) human, mouse, and rat CD36 Application(s): FC, functional blocking, and ICC Functioning as a receptor for oxidized LDL, CD36 is a type-B scavenger receptor that is…
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COX-2 Monoclonal Antibody (Clone CX229)
Cayman ChemicalImmunogen: Synthetic peptide from the C-terminal region of human protein COX-2 Host: Mouse, clone CX229 Isotype: IgG1 Species Reactivity: (+) Human, ovine, and monkey COX-2; (−) Mouse, rat, and rabbit COX-2 and COX-1 (all species) Cross Reactivity: (-) COX-1 (all species) …
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Endothelial Lipase Polyclonal Antibody
Cayman ChemicalAntigen: human endothelial lipase amino acids 19-32 Host: rabbit Cross Reactivity: (+) human, mouse, rat, porcine, and ovine endothelial lipase Application(s): IHC and WB EL is a major genetic determinant for the concentration, structure, and metabolism of HDL, which protects against atherosclerosis.
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11ß-Hydroxysteroid Dehydrogenase (Type 1) Blocking Peptide
Cayman ChemicalPeptide Sequence: human 11β-HSD1 amino acids 78-92 (CLELGAASAHYLAGT) To be used in conjunction with Cayman’s 11β-HSD1 polyclonal antibody (Catalog No. 10004303) to block protein-antibody complex formation during immunochemical analysis of 11β-HSD1.
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Acid Phosphatase Colorimetric Assay Kit
Cayman ChemicalCayman’s Acid Phosphatase Assay provides a convenient method for detecting AP activity in plasma, serum, urine, and semen. The assay utilizes para-nitrophenyl phosphate (pNPP) as a chromogenic substrate for the enzyme. In the first step, AP dephosphorylates pNPP. In the second step, the…
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COX-2 (mouse) Polyclonal Antibody (aa 570-598)
Cayman ChemicalAntigen: mouse/rat COX-2 amino acids 570-598 Host: rabbit Cross-Reactivity: (+) human, guinea pig, monkey, mouse, ovine, rabbit, and rat COX-2; (−) COX-1 (all species) Application(s): ICC, IHC, and WB
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11ß-Hydroxysteroid Dehydrogenase (Type 2) Polyclonal Antibody
Cayman ChemicalAntigen: human 11β-HSD2 amino acids 25-40 (RSDLRLGRPLLAALAL) Host: rabbit Cross Reactivity: (+) human, mouse, and rat 11β-HSD2 Application(s): WB 11β-HSD2 plays a critical role in normal physiology in the corticosteroid regulation of sodium homeostasis and the…
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11ß-Hydroxysteroid Dehydrogenase (Type 2) Blocking Peptide
Cayman Chemical11-Hydroxysteroid dehydrogenase type 2 (11β-HSD2) plays a critical role in normal physiology in the corticosteroid regulation of sodium homeostasis and the pathophysiology of hypertension by converting active cortisol to inactive cortisone. Mutation in the gene encoding 11β-HSD2 results…
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ß-Amyloid (1-8) Peptide
Cayman ChemicalA control peptide for tests that use Cayman’s β-Amyloid (1-8, A2V) Peptide (Item No. 10229).
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Guanylate Cyclase ß1 subunit (soluble) Blocking Peptide
Cayman ChemicalPeptide Sequence: soluble rat guanylate cyclase β1 subunit, amino acids 188-207 (EDFYEDLDRFEENGTQDSR; last D=E in human and bovine) To be used in conjunction with Cayman’s guanylate cyclase β1 subunit (soluble) polyclonal antibody (Catalog No. 160897) to block protein-antibody…
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Luteinizing Hormone ELISA Kit
Cayman ChemicalLuteinizing hormone (LH) is a glycoprotein produced by the pituitary gland and consists of two subunits with a total molecular mass of approximately 30 kDa. The α-subunit is identical to the α-subunit of other pituitary hormones, such follicle stimulating hormone (FSH), thyroid…
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BLT1 Receptor Polyclonal Antiserum
Cayman ChemicalAntigen: human BLT1 receptor amino acids 331-352 (ALEPGPSESLTASSPLKLNELN) Host: rabbit Cross Reactivity: (+) human and bovine BLT1 receptor; (−) mouse BLT1 receptor Applications: CF, FC, IHC (formalin-fixed paraffin-embedded tissue), and WB The human BLT1 receptor is a GPCR that…
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Nod2 Polyclonal Antibody
Cayman ChemicalAntigen: recombinant human Nod2 residues 28-301 Host: rabbit Application(s): WB and IP; may not detect basal levels of Nod2 in monocytes
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SPM D-series LC-MS Mixture
Cayman ChemicalFeatures Each vial contains a mixture of standards packaged in amber ampules purged with argon >1 ml provided at the concentration specified in the insert Designed for direct snap and inject use in mass spectrometry applications Ideally suited for method development and as a…
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Dopamine ß-hydroxylase (C-Term; human) Polyclonal Antibody
Cayman ChemicalAntigen: Peptide from the C-terminal region of human dopamine β-hydroxylase (DBH) Host: sheep Cross Reactivity: (+) Human, mouse, and non-human primate tissue DBH Application: WB
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Autophagy/Cytotoxicity Dual Staining Kit
Cayman ChemicalCayman’s Autophagy/Cytotoxicity Dual Staining provides a convenient tool for studying the regulation of autophagy and cytotoxicity at the cellular level. The kit employs MDC, an autofluorescent substance incorporated into multilamellar bodies by both an ion trapping mechanism and the…
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Prostaglandin I Synthase Monoclonal Antibody (Clone isn-1)
Cayman ChemicalAntigen: bovine lung PGIS Host: mouse, clone isn-1 Cross Reactivity: (+) bovine, mouse, rat, ovine, guinea pig, and rabbit PGIS Isotype: IgG1 Application(s): IHC and IP; WB not recommended PGIS catalyzes the conversion of PGH2 to PGI2 (prostacyclin).
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Propidium Iodide Solution
Cayman ChemicalPI binds to double-stranded DNA and RNA after cells have been permeabilized. Once bound to nucleic acids, the nuclei appear red in color as observed by fluorescence microscopy with a rhodamine filter. PI is useful for multi-color fluorescent staining analysis. The bright red staining of nuclei…
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Deuterated Primary COX and LOX LC-MS Mixture
Cayman ChemicalFeatures Each vial contains a mixture of standards packaged in amber ampules purged with argon >1 ml provided at the concentration specified in the insert Ideally suited for use as an internal standard in mass spectrometry applications This mixture contains deuterated versions…
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S-Nitrosylated Protein Detection Kit (Biotin Switch)
Cayman ChemicalCayman’s S-Nitrosylated Protein Detection Kit (Biotin Switch) employs a modification of the Jaffrey et al. 'Biotin-switch' method to allow for the direct visualization of S-nitrosylated proteins in whole cells or tissues, as well as by WB analysis. Using this method, free SH groups…
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Cholesterol Uptake Cell-Based Assay Kit
Cayman ChemicalMaintaining body cholesterol homeostasis is critical for normal physiological functions and is achieved by a highly regulated balance of de novo synthesis, dietary cholesterol absorption, biliary clearance, and excretion. The mechanisms controlling cholesterol absorption are important to understand…
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Guanylate Cyclase a subunit (soluble) Blocking Peptide
Cayman ChemicalPeptide sequences: human guanylate cyclase α subunit amino acids 418-436 (EQARAQDGLKKRLGKLKAT) To be used in conjunction with Cayman’s guanylate cyclase α subunit polyclonal antibody (Catalog No. 160895) to block protein-antibody complex formation during analysis for guanylate…
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COX-1 (ovine) Polyclonal Antiserum
Cayman ChemicalImmunogen: peptide from an internal region of ovine COX-1 Host: rabbit Cross reactivity: (-) ovine, human, and mouse COX-2 Species reactivity: (+) ovine seminal vesicle, human, bovine endothelial, and porcine COX-1 Applications: WB, ICC, IHC