2-Hydroxypropyl-beta-Cyclodextrin are non-toxic solubilizers. The solubility of drugs increases linearly with the concentration of 2-Hydroxypropyl-b-cyclodextrin in aqueous buffer. The formation of drug/cyclodextrin complexes is a rapidly reversible reaction and complexes exist both in solution and…

Mineral Oil is a colorless, odorless mixture of alkanes from a mineral source. It is often used as an inert overlay to minimize evaporation in molecular biology applications, including PCR, but has many other applications in other research fields.

Ammonium persulfate is a strong oxidizing agent. It is a radical initiator. Ammonium persulfate is a polymerization catalyst used with TEMED for polyacrylamide gel formation. APS has also been utilized to study protein-protein interactions via photoinitiated crosslinking chemistry. Other…

Etoposide is an important chemotherapeutic agent that is used to treat a wide spectrum of human cancers. It also belongs to the drug type plant alkaloid. The primary cytotoxic target for etoposide is topoisomerase II. This ubiquitous enzyme regulates DNA under- and overwinding, and removes knots…

p-Dimethylaminobenzaldehyde is used as a reagent for the determination of amino acids and peptides, amines, indoles, hydrazines and hydrogen peroxides as it forms colored condensation products (Schiff bases) with pyrroles and primary amines; spray reagent for tryptophan; For the determination of…

Cetylpyridinium chloride is used is in some types of mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. It is an antiseptic that kills bacteria and other microorganisms. It has been shown to be effective in preventing dental plaque and reducing gingivitis.

Dimethyl sulfoxide is a dipolar, aprotic solvent. Has been shown to accelerate strand renaturation (1-10% concentration) and is believed to give the nucleic acid thermal stability against depurination. Dimethyl sulfoxide is used to enhance dermal absorption of many chemicals. A solvent for many…

Trichloroacetic acid is an acetic acid analogue commonly used to precipitate proteins, DNA and RNA. In the presence of SDS Trichloroacetic acid will precipitate proteins which can then be quantified by the Lowry method. The compound has also found uses as a decalcifier and fixative in microscopy,…

Dimethyl sulfoxide is a dipolar, aprotic solvent. Has been shown to accelerate strand renaturation (1-10% concentration) and is believed to give the nucleic acid thermal stability against depurination. By heating the solid form to approximately 30°C, the product can be melted without harming…

β-Sitosterol is a common plant steroid that possesses anticholesteremic properties. β-Sitosterol has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways.

N,N,N',N'-Tetramethylethylenediamin is a tertiary amine base. N,N,N',N'-Tetramethylethylenediamine is used to catalyze the formation of free radicals from ammonium persulfate or riboflavin. The free radicals will cause acrylamide and bis-acrylamide to polymerize to form a gel…

Protein purification reagent Triethanolamine acts as an organic additive in the grinding of cement clinker and as a complexing agent for aluminum ions in aqueous solutions. It is used as an emulsifier and a surfactant. It finds application in common products like dishwashing liquids, general…

The molecule is a dialdehyde, consisting of two formyl (CHO) groups attached to adjacent carbon centres on a benzene ring. o-Phthalaldehyde is used for precolumn derivatization of amino acids for HPLC separation and for flow cytometric measurements of protein thiol groups. Used for fluorometric…

p-Toluenesulfonic acid monohydrate is an organic-soluble acid catalyst in organic synthesis. The catalyst has been incorporated in the esterification of carboxylic acids or transesterification of esters. p-Toluenesulfonic acid monohydrate has been used as a reducing agent for the reductive…

2-Mercaptoethanol is a hybrid of ethylene glycol and 1,2-ethanedithiol. It is used to reduce disulfide bonds and can act as a biological antioxidant by scavenging hydroxyl radicals. It is widely used because the hydroxyl group confers solubility in water and lowers the volatility. Due to its…

Paraformaldehyde (PFA) is the smallest polyoxymethylene. It is polymerization product of formaldehyde. Paraformaldehyde has been used in the past for disinfecting sickrooms, clothing, linen and sickroom utensils. It has been used as a fumigant and in manufacturing synthetic resins & as a…

A mineral oil is any of various colorless, odorless, light mixtures of alkanes in the C15 to C40 range from a non-vegetable (mineral) source, particularly a distillate of petroleum.Most often, mineral oil is a liquid by-product of the distillation of petroleum to produce gasoline and other…

Stearic acid is a long-chain saturated fatty acid that can be derived from either animal fats or vegetable oils. Compared to other long-chain saturated fatty acids that are hypercholesterolemic, experimental diets high in stearic acid (9.3-11.8% of energy) do not raise plasma total cholesterol or…

Heparin is a polymer classified as a mucopolysaccharide or a glycosoaminoglycan. It is biosynthesized and stored in mast cells of various mammalian tissues, particularly liver, lung and mucosa. It is made up of repeated disaccharide units consisting of 1,4-linked L-iduronic acid and D-glucosamine.…

Citrinin is a fungal metabolite found in moldy rice. Citrinin was used to evaluate toxicity of the mycotoxin citrinin using yeast ORF DNA microarray and Oligo DNA microarray.

Oleic acid is a mono-unsaturated omega-9 fatty acid created by dehydrogenation of stearic acid. It is then further dehydrogenated and elongated to create members of the n-9 family of fatty acids. Oleic acid is used as emollient. Small amounts of oleic acid are used as an excipient in…

Palmitic acid, or hexadecanoic acid is one of the most common 16 carbon saturated fatty acids found in animals and plants. It occurs as the glyceryl ester in many oils and fats. Palmitic acid has been reported to target proteins to cell membranes. It has been found to promote triglyceride…

Tween 80 is a polyethylene sorbitol ester, non ionic surfactant and an emulsifier derived from polyethoxylated sorbitan and oleic acid. Tween 80 has been widely used in biochemical applications including: solubilizing proteins, isolating nuclei from cells in culture, growing of tubercule…

Dimethyl Sulfoxide is a dipolar, aprotic solvent. It has been shown to accelerate strand renaturation (1-10% concentration) and is believed to give the nucleic acid thermal stability against depurination. Dimethyl Sulfoxide is used to enhance dermal absorption of many chemicals, as a solvent for…

Chromium potassium sulfate is the potassium double sulfate of chromium. Chromium alum is used in the tanning of leather. It was also used in gelatine emulsions in photographic film as hardener.

Ferric chloride is a moderately strong Lewis acid. Ferric Chloride is used in photoengraving, photography, the manufacture of pigments and ink, the chlorination of silver and copper ores, and as a mordant in dyeing and printing textiles. It is also utilized in the synthesis of organic compounds.…

Propylene glycol is a clear, colorless and hygroscopic liquid. Propylene glycol contains an asymmetrical carbon atom, so it exists in two stereoisomers. The freezing point of water is depressed when mixed with propylene glycol due to increased opportunity for hydrogen bonding. Propylene glycol…

Folic acid, also known as folate, is a B vitamin that can be found in a variety of fruits and vegetables. Can be chemically synthesized Water soluble Exhibits metal binding properties Folic acid (Vitamin B9 and folate) is essential to numerous bodily functions. The human body needs…

Lidocaine is the first amino amide–type local anesthetic. Lidocaine is used topically to relieve itching, burning and pain from skin inflammations, injected as a dental anesthetic or as a local anesthetic for minor surgery. A common local anesthetic and antiarrhythmic drug. Na+ channel…

Mineral oil is used as an overlay covering microdrops of culture medium in petri dishes, during the culture of oocytes and embryos in IVF and related procedures. It also has its applications in food processing, cosmetics and pharmaceuticals. A mineral oil is any of various colorless, odorless,…

p-Aminobenzoic acid is an organic compound used in the treatment of fibrotic skin disorders like Peyronie's disease. It is employed as an intermediate in the synthesis of folate (Vitamin BX), azo dyes and cross linking agents. It is also useful in biomedical sector for the preparation of local…