Palmitic acid, or hexadecanoic acid is one of the most common 16 carbon saturated fatty acids found in animals and plants. It occurs as the glyceryl ester in many oils and fats.
Palmitic acid has been reported to target proteins to cell membranes. It has been found to promote triglyceride accumulation and also affect cell viability. Triglyceride accumulation in goose hepatocytes shows the ability to induce apoptosis. Mechanistic studies show that Palmitic Acid has also demonstrated the ability to induce opening of Ca2+-dependent pores in plasma membranes of red blood cells which will eventually lead to lysis of the cells. Additional studies suggest that saturated fatty acids can induce the expression of Cox-2 and NFκB (nuclear factor κB) activation. Palmitic acid is used in determination of water hardness.
Key Applications: Apoptosis Induction, Determination of Water Hardness
Product Type: Biochemicals
Biochemical Category: Lipids
Chemical Class: Lipids
Density: 0.853 at 62°C (water = 1)
Boiling Point: 352°C (665 °F)(Lit.)
Melting Point: 58 - 66°C
Vapor Pressure: 10 mm Hg at 210 °C)(Lit.)
Presentation: White Powder
Detection Method: FTIR
Solubility: Soluble in DMF (0.5% w/v - clear and colorless); cold alcohol (sparingly), petroleum ether (sparingly), hot alcohol (freely), ether (freely), propyl alcohol (freely), and chloroform (freely). Insoluble in water.
Storage & Handling: -20°C