Cayman Chemical Protein
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Histone H2A (Xenopus recombinant)
Cayman ChemicalSource: Recombinant protein expressed in E. coli Mr: 13.9 kDa Histone 2A is one of the four histones that comprise a nucleosome protein core.
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SET7/9 (human recombinant)
Cayman ChemicalSource: Active recombinant N-terminal His-tagged SET7/9 purified from E. coli Mr: 43.3 kDa SET7/9 is exclusively a mono-methylase that methylates histone H3, tumor suppressor p53, and transcription factor TAF10. SET7/9 methylates p53 in response to DNA damage thereby activating p53 for…
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Dieosinediglutathione
Cayman ChemicalDieosinediglutathione is the product of glutathione disulfide and eosin isothiocyanate which has been purified and lyophilized. This glutathione disulfide derivative has low fluorescence due to self-quenching. The monomer eosinglutathione (EGSH) has high fluorescence. This product can be used for…
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JMJD2A-Strep tagged (human recombinant)
Cayman ChemicalSource: Active recombinant N-terminal Strep II-tagged protein expressed in E. coli Mr: 42.7 kDa JMJD2A catalyzes the demethylation of trimethylated forms of histone at lysine residues 9 and 36. JMJD2A is an α-ketoglutarate-dependent Fe (II) oxygenase. Purification of Fe-dependent JmjC…
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Serum Retinol Binding Protein 4 (human recombinant)
Cayman ChemicalSource: recombinant His-tagged protein purified from E. coli Mr: ~21 kDa
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BRD4 bromodomain 1 (human recombinant; His-tagged)
Cayman ChemicalSource: Recombinant N-terminal His-tagged protein expressed in E. coli Mr: 16.6 kDa The isolated individual or tandem bromodomains of BRD4 have been shown to bind acetylated histone tails, serving to couple histone acetylation marks to the transcriptional regulation of target promoters.
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Tetanus Toxoid
Cayman ChemicalAn inactive neurotoxin used as a vaccine to produce immunity to tetanus; functions as a carrier of conjugated polysaccharides in the development of vaccines against encapsulated bacterial pathogens.
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Human Fibrinogen (PAD4 Citrullinated)
Cayman ChemicalSource: Fibrinogen purified from human plasma citrullinated with human recombinant PAD4 plasma Uncitrullinated Fibrinogen Mr: α chain isoform 1 (95 kDa), α chain isoform 2 (69.8 kDa), β chain (55.9kDa) and isoform γ-B chain (51.5 kDa)
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HMG-CoA Reductase (human recombinant)
Cayman ChemicalSource: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 76.5 kDa
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Thrombin (human)
Cayman ChemicalSource: Human blood; all source material tested and found non-reactive to HTLV-III and HBsAg using FDA approved assay methods Mr: 38 kDa
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FABP5 (human recombinant)
Cayman ChemicalSource: recombinant N-terminal hexahistidine-tagged protein expressed in E. coli Mr: 18 kDa
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FEN1 (human recombinant)
Cayman ChemicalPeptide sequence: 2-380 Full-length Source: recombinant C-terminal His-tagged protein expressed in E. coli Mr: 43.8 kDa
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Spectral Characteristics: Visible absorption maximum = 483 nm, Emission maximum = 673 nm; Peridinin Chlorophyll (PerCP), crosslinked with SMCC for stability.
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NF-?B (p50) (human recombinant)
Cayman ChemicalSource: recombinant enzyme expressed in E. coli Mr: 74.5 kDa As part of a dimer, this transcription factors binds with p65 to form NF-κB, which is responsible for regulating the expression of inflammatory cytokines, chemokines, immunoreceptors, and cell adhesion molecules
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Histone H2B (Xenopus recombinant)
Cayman ChemicalSource: Recombinant protein expressed in E. coli Mr: 13.7 kDa. Histone 2H2B is one of the core nucleosomal histones. It undergoes many modifications which include acetylation, methylation, and phosphorylation that are important for regulation of gene transcription.
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COX-1 (human recombinant)
Cayman ChemicalPeptide sequence: 24-599 (full-length) Source: Recombinant N-terminal His-tagged protein expressed using the baculovirus system Mr: ~70 kDa
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COX-2 (ovine) Electrophoresis Standard
Cayman ChemicalCyclooxygenase catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins: the conversion of arachidonic acid to prostaglandin H2. Recent discoveries of the induction of cyclooxygenase by a variety of stimuli such as phorbol esters, lipopolysaccharides, and…
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Glucose-6-phosphate Isomerase (human recombinant)
Cayman ChemicalRecombinant C-terminal His-tagged protein expressed in E. coli One unit is defined as the amount of enzyme required to reduce 1 µmol of NADP+ to NADPH per minute at 25°C in 50 mM Triethanolamine, pH 7.6, containing 1 mM MgCl2.
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SIRT7 (human recombinant)
Cayman ChemicalSource: Recombinant N-terminal His-tagged enzyme expressed in E. coli Mr: 49.3 kDa SIRT7 activates transcription by RNA polymerase I and deacetylates p53. It prevents progressive deterioration of the heart, and is suggested to play an important role in regulation of stress responses and cell…
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CBX1 (human recombinant)
Cayman ChemicalSource: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 48.9 kDa
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JMJD2A (human recombinant)
Cayman ChemicalSource: Active recombinant N-terminal His-tag protein expressed in E. coli Mr: 43 kDa JMJD2A catalyzes the demethylation of trimethylated histone at lysine residues 9 and 36.
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FABP1 (human recombinant)
Cayman ChemicalSource: recombinant N-terminal hexahistidine-tagged protein expressed in E. coli Mr: 18.3 kDa
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pCAF Histone Acetyltransferase
Cayman ChemicalSource: Active recombinant GST-tagged protein expressed in E. coli Mr: ~40 kDa pCAF belongs to the GCN5/pCAF family of nuclear HATs. Cayman’s pCAF preparation contains 165 amino acids from the HAT activity domain of human pCAF fused to GST at the N-terminus. Enzyme activity was…
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Prostaglandin F Synthase (human recombinant)
Cayman ChemicalSource: Active recombinant C-terminal His-tagged protein expressed in E. coli Mr: ~37 kDa Protein concentration: 0.8 mg/ml Human PGFS catalyzes the isomerization of PGH2 to PGF2a (PGH2 9,11-endoperoxide reductase activity), as well as the formation of 11b-PGF2a from PGD2 (PGD2…
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IDH1 (human recombinant)
Cayman ChemicalSource: Recombinant C-terminal His-tagged protein expressed in E. coli MW: 47.9 kDa
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MeCP2 (human recombinant; methyl binding domain aa 77-166)
Cayman ChemicalSource: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 37 kDa MeCP2 specifically binds to methylated promoters on CpG islands and mediates gene silencing by recruiting corepressor complexes. In vitro work suggests high affinity binding of MeCP2 is facilitated by DNA…
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IDH1 R132H mutant (human recombinant)
Cayman ChemicalSource: Active recombinant C-terminal His-tagged protein expressed in E. coli MW: 47.9 kDa
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CBX3 (human recombinant)
Cayman ChemicalSource: Recombinant N-terminal GST-tagged protein expressed in E. coli Mr: 48.4 kDa
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Sphingosine Kinase 1 (human recombinant)
Cayman ChemicalSource: human recombinant N-terminal His-tagged protein from Sf9 cells SPHK1 catalyzes the production of sphingosine-1-phosphate, a lipid mediator with broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.