MP Biomedicals, 100 mg
MP Biomedicals
MP Biomedicals is a worldwide corporation manufacturing and distributing systems, kits and reagents for the life science research, medical device, biopharma manufacturing and diagnostics markets. Our extensive portfolio and custom services deliver the dependability that research and industrial communities rely on to worry less and discover more. From small scale research to large scale manufacturing, MP Biomedicals has been advancing life science projects for over 50 years.
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(-)-Epigallocatechin gallate
MP BiomedicalsPotent anticancer compound. Anti-angiogenic. VEGF, VE-cadherin phosphorylation, matrix metalloproteinase and urokinase-plasminogen activator (uPA) inhibitor. Anti-inflammatory. NF-kappaB inhibitor. Modulates chronic inflammatory diseases, such as type 2 diabetes, rheumatoid arthritis, inflammatory…
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Vancomycin Hydrochloride from Streptomyces orientalis
MP BiomedicalsVancomycin inhibits bacterial mucopeptide biosynthesis. Vancomycin is a glycopeptide antibiotic that blocks bacterial cell wall biosynthesis at the level of peptidoglycan biosynthesis. It inhibits incorporation of terminal D-alanyl-D-alanine moieties of the NAM/NAG-peptides. It is effective against…
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Puromycin Dihydrochloride
MP BiomedicalsPuromycin is an antibiotic of unique structure and biological activity. It is produced by fermentation using Streptomyces albo-niger. There are four aspects of puromycin's biological activity that are 1) antitumor effect; 2) nephrotoxic action; 3) inhibition of purine and/or protein synthesis…
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ß-Nicotinamide Adenine Dinucleotide Reduced Disodium Salt
MP Biomedicalsβ-NADH, a pyridine nucleotide and biologically active form of nicotinic acid, is a coenzyme necessary for the catalytic reaction of certain enzymes. β-NAD+ is a carrier for hydride ion, forming β-NADH. The hydride ion is enzymatically removed from a substrate molecule by the action…
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ß-Nicotinamide Adenine Dinucleotide
MP Biomedicalsβ-NAD is one of the biologically active forms of nicotinic acid. Occurs in living cells, primarily in the oxidized state Coenzyme for dehydrogenases NAD usually acts as a hydrogen acceptor, forming NADH Major electron acceptor molecule in biological oxidations. Acts as a…
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Boc-Val-Leu-Gly-Arg-pNA acetate salt
MP BiomedicalsBoc-VLGR-pNA acetate salt (sequence Boc-Val-Leu-Gly-Arg-pNA), is a chromogenic substrate for horseshoe crab clotting enzyme. It has been widely used in detection assays for bacterial endotoxins. 25 mg, 100 mg
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Collagenase Type I from Clostridium histolyticum
MP BiomedicalsCollagenase is a protease which cleaves the triple-helical protein called collagen. There are three types of tissue collagenases, and these belong to the matrix metalloproteinases (MMP) family. Collagenase from Clostridium histolyticum has extensive use in biological studies, where it is used to…
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B-Nicotinamide Adenine Dinucleotide, Oxidized Form
MP BiomedicalsThis is an ultrapure NAD, chromatographically purified to remove trace inhibitors. β-NAD, a pyridine nucleotide and biologically active form of nicotinic acid, is a coenzyme necessary for the catalytic reaction of certain enzymes. It occurs in living cells primarily in the oxidized state.…
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N-Acetyl-D-Galactosamine
MP BiomedicalsN-Acetyl-D-galactosamine(GalNAc), an aminosugar, is a component of many O-linked and N-linked glycan structures. Intial O-linked sugar to many serine and threonine residues in protein glycosylations.
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Hyaluronidase from Ovine Testes
MP BiomedicalsHyaluronidase is a glycoprotein containing 5% mannose and 2.17% glucosamine, it catalyzes the random hydrolysis of 1,4-linkages between 2-acetamido- 2-deoxy- β-D-glucose and D-glucose residues in hyaluronate. Hyaluronidase from bovine testes is a tetramer consisting of 4 equal subunits with a…
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Papain from Papaya Latex
MP BiomedicalsPapain is a sulfhydryl protease from Carica papaya latex. Cleaves peptide bonds of basic amino acids, leucine, or glycine Hydrolyzes esters and amides One unit will hydrolyze 1.0 µmole of N-alpha-benzoyl-L-arginine ethyl ester (BAEE) per minute at 25°C and pH 6.2 Papain…
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Azoxymethane
MP BiomedicalsAzoxymethane (AOM) is a carcinogen that induces O6-methylguanine adducts in DNA leading to G to A transitions.
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Pepstatin A
MP BiomedicalsTight-binding, reversible, highly selective inhibitor of acid proteases (aspartyl peptidases), like pepsin, gastricsin, cathepsin E and D, renin, chymosin, bacterial aspartic proteinases and HIV proteases. Does not inhibit thiol proteases, neutral proteases or serine proteases. Widely used as a…
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Poly-D-Lysine Hydrobromide
MP BiomedicalsPoly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding. A compromise between the easier to use lower molecular weight products…
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Aprotinin from Bovine Lung
MP BiomedicalsAprotinin is a single chain polypeptide (58 amino-acids) crosslinked by three disulfide bridges, showing competitive and reversible inhibiton of proteolytic and esterolytic activity. Aprotinin forms stable complexes with, and blocks the active sites of serine protease enzymes. It is found in bovine…
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Collagenase Type IV from Clostridium histolyticum
MP BiomedicalsCollagenases degrade native helical collagen fibrils. It has an important role in connective tissue metabolism and is produced by specific cells involved in repairs and remodelling processes. Collagenase is used for tissue dissociation combined with other enzymes such as elastase, trypsin,…
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Cefsulodin Sodium Salt
MP BiomedicalsCefsulodin is a third generation cephalosporin antibiotic that has very specific activity against Pseudomonas aeruginosa. It has no significant activity against other Gram-negative bacteria and very limited activity against Gram-positive bacteria and anaerobic bacteria. Cefuslodin is most…
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Dexamethasone
MP BiomedicalsDexamethasone is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S…
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Elastase from Porcine Pancreas
MP BiomedicalsElastase is an enzyme from the class of proteases (peptidases) that break down proteins. It hydrolyzes peptide bonds, especially those adjacent to neutral amino acids. Hydrolyses elastin Digests hemoglobin, casein, and fibrin One unit will solublize 1 mg of elastin in 20 minutes at…
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Linoleic Acid, Sodium Salt
MP BiomedicalsLinoleic acid (LA) is an unsaturated n-6 fatty acid; it belongs to one of the two families of essential fatty acids. The body cannot synthesize linoleic acid from other food components. Linoleic acid can be used to show the antioxidant effect of natural phenols.
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Poly-L-Lysine, MW >=70,000
MP BiomedicalsPoly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein. It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When…
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Bilverdin Dihydrochloride
MP BiomedicalsBiliverdin Dihydrochloride is a bile pigment component. An oxidized metabolite of bilirubin caused when bilirubin reacts with reactive oxygen species. Biliverdin IX is composed of alpha, beta, gamma and delta isomers. Biliverdin dihydrochloride was found responsible for cytoprotection. It was…
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Lectin, Wheat Germ Agglutinin from Triticum vulgaris
MP BiomedicalsLectins are proteins or glycoproteins of non-immune origin that agglutinate cells and/or precipitate complex carbohydrates. Lectins are capable of binding glycoproteins even in presence of various detergents. The agglutination activity of these highly specific carbohydrate-binding molecules is…
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Poly-D-Lysine Hydrobromide from Synthetic
MP BiomedicalsPoly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein. Molecular weight has been determined by Viscosity as well as by HPLC. It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction…
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Hyaluronidase from Bovine Testes
MP BiomedicalsHyaluronidase is a glycoprotein containing 5% mannose and 2.17% glucosamine, it catalyzes the random hydrolysis of 1,4-linkages between 2-acetamido- 2-deoxy- b-D-glucose and D-glucose residues in hyaluronate. Hyaluronidase from bovine testes is a tetramer consisting of 4 equal subunits with a…
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Poly-L-Lysine Hydrobromide
MP BiomedicalsPoly-L-lysine is a positively charged amino acid polymer. Poly-lysine binds to DNA, red cell membrane and any negatively charged protein. It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell…
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Naloxone Hydrochloride
MP BiomedicalsNaloxone is specific and competitive opiate antagonist at mu, kappa, delta and sigma receptors; it blocks the action of sigma-agonists at opioid sites. It displaces morphine and other opiate agonists from the opiate receptor. It is more potent than Nalorphine and is also an effective antagonist for…
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Apoferritin from Horse Spleen
MP BiomedicalsApoferritin is the Protein shell of ferritin. Calibration of gel filtration columns and sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis Acts as an anti-oxidant When added to cultured endothelial cells apoferritin is taken up in a dose-responsive manner and appears to…
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4-(2-Aminoethyl)-Benzenesulfonyl Fluoride Hydrochloride
MP BiomedicalsAEBSF hydrochloride is a covalent binding serine protease inhibitor, belongs to the family of irreversible sulfonyl fluoride inhibitors that block trypsin and chymotrypsin-type enzymes. Similar in structure to the commonly used inhibitor PMSF, AEBSF offers better solubility in water, lower…
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Collagenase Type II from Clostridium histolyticum
MP BiomedicalsCollagenases degrade native helical collagen fibrils. Plays an important role in connective tissue metabolism Produced by specific cells involved in repairs and remodeling processes Type II enzyme that contains greater clostripain activity Collagenase is used for collagen…
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Collagen Type I from Calf Skin
MP BiomedicalsSuitable for cell adhesion in tissue culture, as well as gel formation, platelet aggregation, and as a substrate for collagenase. Collagen is a group of naturally occurring proteins found in animals, especially in the flesh and connective tissues of vertebrates. It is the main component of…