IGEPAL™ CA-630 is a homologous series of octylphenoxypoly(ethyleneoxy)ethanols used for the solubilizing and isolation of membrane proteins. The Igepal CA surfactants are all derived from the same hydrophobic starting material, octylphenol. By increasing the amount of hydrophilic…

Synonyms: 1,2,3-Tricaprinoylglycerol, 1,2,3-Tridecanoylglycerol, Glycerol tricaprate, Glycerol tris(decanoate), Tridecanoin, Glyceryl tridecanoate, 1,2,3-Tridecanoyl-rac-glycerol, Glyceryl tridecanoate, Tri-N-Caprin Molecular Formula: C₃₃H₆₂O₆

Citric acid is a key metabolic intermediate. Citrate is the starting point of the tricarboxylic acid cycle. Its concentration also coordinates several other metabolic pathways. Citric acid can form complexes with various cations, particularly with iron and calcium. In animals, citric acid improves…

Retinoic acid (RA) is a vitamin A-derived, non-peptidic, small lipophilic molecule that mediates the functions of vitamin A required for growth and development. It affects gene transcription and modulates a wide variety of biological processes like Cell Proliferation, Differentiation, including…

2-Merceptoethanol is used to reduce disulfide bonds and can act as a biological antioxidant by scavenging hydroxyl radicals. 2-Merceptoethanol is used to reduce disulfide linkages in solubilizing proteins for gel electrophoresis. 2-mercaptoethanol is readily oxidized in air to a disulfide,…

Zeolite, a microporous, aluminosilicate mineral, is used as a molecular sieve and as an adsorbent of a wide variety of cations, such as Na+, K+, Ca2+, Mg2+ and others. Hydrated alkali-aluminum silicate. Zeolites occur naturally in sedimentary and volcanic rocks, altered basalts, ores, clay…

Tween 80 is a polyethylene sorbitol ester, non ionic surfactant and an emulsifier derived from polyethoxylated sorbitan and oleic acid. Tween 80 has been widely used in biochemical applications including: solubilizing proteins, isolating nuclei from cells in culture, growing of tubercule…

Urea is a prinicipal protein metabolite end product of nitrogen metabolism in most mammals, formed by the enzymatic reactions of the Kreb's cycle and the major product for the removal of free ammonia (NH4+) in vivo. Urea is a mild agent usually used in the solubilization and denaturation of…

β-Sitosterol is a common plant steroid that possesses anticholesteremic properties. β-Sitosterol has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways.

Bumetanide has been used to probe the role of prostaglandin E2 in the regulation of chloride secretion across porcine endometrial epithelial cells.

Thiobarbituric acid (TBA) reaction has been used to detect lipid oxidation. When lipids are oxidized, malonaldehyde is formed. TBA reacts with malonaldehyde in hot acid to form a red complex of malonaldehyde:TBA (1:2). Used to quantitate lipopolysaccharides, carrageenan, and sialic acids; used…

Protein purification reagent Triethanolamine acts as an organic additive in the grinding of cement clinker and as a complexing agent for aluminum ions in aqueous solutions. It is used as an emulsifier and a surfactant. It finds application in common products like dishwashing liquids, general…

Aldolase is used in an hydrazine assay based on Boyer's modification in which 3-phosphoglyceraldehyde reacts with hydrazine to form a hydrazone which absorbs at 240 nm.

Lidocaine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Lidocaine is also an anasthetic and class Ib antiarrhythmic agent. This compund is known to block voltage-gated sodium channels in the inactivated state. Lidocaine is a second-generation…

Polysorbate 20 is typically used as an emulsifying agent for the preparation of stable oil-in-water emulsions, particularly in pharmaceutical applications. It has been used in pre-extraction of membranes to remove peripheral proteins. It has been used as a blocking agent on nitrocellulose. …

Applications Bentonit is used as Aluminum Silicate (clay), Emulsifier and adsorbent for proteins and virus particles. Synonyms: Montmorillonite CAS Number: 1302-78-9 Molecular Formula: Principally montmorillonite - Al₂O₃ • 4SiO₂ •…

RNase Erase™ removes Rnase contamination from glass, plastic, pipettes and equipments that must be Rnase free. RNase Erase™ was formulated using three ingredients known to be active against RNase. It effectively removes high levels of RNase contamination that similar products…

Ammonium acetate is a chemical compound which is derived from the reaction of ammonia and acetic acid. Ammonium acetate is volatile at low pressures. Because of which it has been used to replace cell buffers with non-volatile salts, in preparing samples for mass spectrometry. It is used as a buffer…

Trichloroacetic acid is an acetic acid analogue commonly used to precipitate proteins, DNA and RNA. In the presence of SDS Trichloroacetic acid will precipitate proteins which can then be quantified by the Lowry method. The compound has also found uses as a decalcifier and fixative in microscopy,…

Dexamethasone is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S…

Beta-glucuronidases are members of the glycosidase family of enzymes that catalyze the breakdown of complex carbohydrates. Human β-glucuronidase is a type of glucuronidase that catalyzes hydrolysis of β-D-glucuronic acid residues from the non-reducing end of mucopolysaccharides, such as…

Ricinoleic Acid is used as a substrate for the synthesis of the conjugated linoleic acids.

Cetylpyridinium chloride is used is in some types of mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. It is an antiseptic that kills bacteria and other microorganisms. It has been shown to be effective in preventing dental plaque and reducing gingivitis.

Polyethyleneimine is a branched chain polymer having a ratio of 1:2:1 of primary:secondary:tertiary amines with a branching site every 3 to 3.5 nitrogen atoms and a base structure of (CH₂CH₂NH)x. The nitrogen atoms must be protonated to achieve cationic charge, so the cationic…

Ammonium persulfate is a strong oxidizing agent. It is a radical initiator. Ammonium persulfate is a polymerization catalyst used with TEMED for polyacrylamide gel formation. APS has also been utilized to study protein-protein interactions via photoinitiated crosslinking chemistry. Other…

4-Aminoantipyrine is a reagent for determination of chlorinated phenols, phenylglycosidase, and glucose in the presence of phenol and peroxidase.

UniverSol is a very efficient environmentally safe, non-toxic, biodegradable liquid scintillation cocktail of the "gelling" variety. Environmentally Safe Biodegradable Non-toxic Non-flammable Primary Applications: Aqueous samples from 0 to 15% count as…

Naloxone is specific and competitive opiate antagonist at mu, kappa, delta and sigma receptors; it blocks the action of sigma-agonists at opioid sites. It displaces morphine and other opiate agonists from the opiate receptor. It is more potent than Nalorphine and is also an effective antagonist for…

Vitamin K is a group of structurally similar, fat-soluble vitamins. Vitamin K1 is used as a cofactor in the formation of coagulation factors II (prothrombin), VII, IX and X; anticoagulant factors protein C and S and as a cell signaling factor.

Triton® X-100 is a alkylaryl polyether alcohol. It is a nonionic surfactant prepared by the reaction of octylphenol with ethylene oxide. The number ("-100") relates only indirectly to the number of ethylene oxide units in the structure. The principal uses of Triton® X-100 is…