MP Biomedicals Antibiotics, Antimycotics & Preservatives
MP Biomedicals
MP Biomedicals is a worldwide corporation manufacturing and distributing systems, kits and reagents for the life science research, medical device, biopharma manufacturing and diagnostics markets. Our extensive portfolio and custom services deliver the dependability that research and industrial communities rely on to worry less and discover more. From small scale research to large scale manufacturing, MP Biomedicals has been advancing life science projects for over 50 years.
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Bafilomycin A1 (high purity)
MP BiomedicalsMacrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Distinguishes among different types of ATPases. Inhibitor of endosomal, lysosomal and vacuolar acidification. Prevents lysosomal Ca2+ uptake. Inhibitor of autophagic degradation by rising pH and thus inactivating the lysosomal acid…
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Tobramycin
MP BiomedicalsTobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius and used to treat various types of bacteria infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas. It works by binding to a site on bacterial 30S and 50S ribosome,…
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Thiamphenicol
MP BiomedicalsThiamphenicol (also known as thiophenicol and dextrosulphenidol) is an antibiotic. It is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Like chloramphenicol, it is insoluble in water, but highly soluble in lipids. …
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Amphotericin B from Streptomyces sp.
MP BiomedicalsAmphotericin B is an antimicrobial/antifungal agent effective against yeast and other fungi. It is a mixture of polyenes. It interrupts cell membrane permeability by binding sterols resulting in the loss of low molecular weight compounds from the cell. Amphotericin B may be toxic to some insect…
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PMA
MP BiomedicalsProduct Description Most commonly-used phorbol ester. Binds to and activates protein kinase C (PKC) at nM concentrations. Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by…
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Aztreonam
MP BiomedicalsAztreonam is the first totally synthetic monocyclic β-lactam antibiotic that displays a high degree of resistance to β-lactamase degradation. It has high specificity for gram-negative aerobic rods. Aztreonam specifically targets the penicillin binding protein 3 (PBP-3) of Gram-negative…
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Erythromycin
MP BiomedicalsErythromycin is a macrolide antibiotic that bind to the 50S ribosomal subunit and inhibit protein synthesis. This is an antimicrobial substance produced by the growth of certain strains of Streptomyces erythreus. It is a mixture consisting largely of erythromycin A with lesser amounts of…
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Hygromycin B from Streptomyces hygroscopicus
MP BiomedicalsHygromycin B is an antibiotic substance isolated from Streptomyces hygroscopicus. Its mode of action is the inhibition of protein synthesis, by inducing the misreading of the m-RNA template in the prokaryote, (E. coli, at 100 mg/mL), lower eukaryotes (e.g., yeast, at 200 mg/mL) and higher…
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Ciprofloxacin Hydrochloride
MP BiomedicalsCiprofloxacin is a fluorinated quinolone antibacterial agent which is highly effective against a broad spectrum of bacteria and mycoplasma. Ciprofloxacin is most commonly used to treat infections of the skin, bone, sinus, lung, abdomen, and bladder. It can also be used to treat some sexually…
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Ivermectin
MP BiomedicalsIvermectin is a macrolide antiobiotic, & semisynthetic derivative of avermectin B1a and B1b. Ivermectin is a broad-spectrum antiparasitic agent. Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptor; also modulates glutamate-GABA-activated chloride channels.
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Tobramycin
MP BiomedicalsTobramycin is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius. It is effective against gram-negative bacteria, especially the Pseudomonas species. Tobramycin has been used: to study the effect of tobramycin on bacteriophage infected biofilms to study…
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Paromomycin Sulfate
MP BiomedicalsParomomycin Sulfate is an aminoglycoside antibiotic which inhibits protein initiation. Paromomycin sulfate salt has been used as a reference compound in antileishmanial activity RNA-binding ligand and interacts with aptamer. This interaction prevents the binding (and cutting) of dicer…
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Alamethicin from Trichoderma viride
MP BiomedicalsAlamethacin is a mixture of alamethicin homologs. It is a membrane permeabilizing antibiotic. Alamethicin applications includes increasing [32P] incorporation into phosphatidylinositol 4-phosphate and mermeabilization of sarcoplasmic reticulum vesicles.It causes fusion of lipid vesicles. It…
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Paclitaxel from Taxus brevifolia (Pacific Yew Bark)
MP BiomedicalsPaclitaxel has been used as a component of the dechorionation buffer for Gryllus bimaculatus eggs. Paclitaxel has also been used for studying its effect on the movement of all-trans retinoic acid (ATRA) differentiated NB4 cells. Antitumor and antileukemic agent which lowers the critical…
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Rapamycin
MP BiomedicalsAntibiotic. Antibacterial and antifungal properties. Forms a complex with FKBP12 and inhibits the mammalian target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an alternative to calcineurin…
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Compound 48/80
MP BiomedicalsCompound 48/80 is a oligomeric mixture of condensation products from N-methyl-p-methoxyphenethylamine and formaldehyde. It is a mixture of low-molecular weight polymers having a degree of polymerization between 3 to 6. Protein G activator similar to mastoparan. Calmodulin and platelet PLC…
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Dihydrostreptomycin Sulfate
MP BiomedicalsDihydrostreptomycin Sulfate is an aminoglycoside antibiotic. It inhibits protein synthesis by interfering with translation. Used in aminoglycoside uptake studies Inhibits bacterial protein synthesis at the level of the 30S ribosomal subunit and the 16S rRNA Preparation Method: Add the…
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Oligomycin from Streptomyces diastatochromogenes
MP BiomedicalsOligomycin is a natural antibiotic isolated from Streptomyces diastatochromogenes, which is a mixture of oligomycins A, B, and C. Oligomycin is used as antibiotic which inhibits respiration in mitochondria. It inhibits ATP synthase by blocking its proton channel (F0 subunit), which is necessary…