Corning Gentest cryopreserved animal hepatocytes allow researchers to study toxicological and pharmacokinetic properties of new chemical entities (NCEs) in vitro prior to expensive in vivo animal testing. Understanding species differences in metabolism is critical to selecting appropriate preclinical species for toxicity and pharmacokinetic studies. Corning Gentest animal cryohepatocytes are suitable for use in metabolic stability, metabolite profiling, and cytotoxicity studies.
Convenience – animal cryopreserved hepatocytes for rat, mouse, dog, and monkey are available as cryopreserved vialed suspension cells; just thaw and perform studies when needed
Full characterization – tested for high viability and phase I and II metabolic enzymes