Macrophage inflammatory protein-1 alpha (MIP-1 a), also known as CCL3, is a cytokine produced by macrophages. MIP-1 a binds the chemokine receptors CCR1, CCR4 and CCR5 to induce inflammatory responses, including the recruitment of granulocytes and neutrophil superoxide production. The MIP-1 a and MIP-1 ß heterodimer exhibits antiviral activity against the human immunodeficiency virus 1 (HIV-1).
Bioactivity: No biological activity data is available at this time