Basic fibroblast growth factor (FGF-basic), also known as FGF-2, is expressed by endothelial cells and is a mediator of angiogenesis. FGF-basic also has cardioprotective functions during heart injury. FGF-basic binds heparin in order to signal through fibroblast growth factor (FGF) receptor tyrosine kinases.
Bioactivity Assay:NR6R 3T3 proliferation; ED50 =1 ng/mL; Bioactivity =1.0 x 10^6 units/mg