Stromal cell-derived factor-1 alpha (SDF-1 a), also called CXCL12a, is one of two SDF-1 splice variants made by a wide variety of cells upon stimulation by inflammatory cytokines such as TNF, IL-1, and LPS. SDF-1a signals through the G protein-coupled receptor CXCR4 to recruit activated leukocytes. Human and mouse SDF-1 a share 99% sequence identity.
Bioactivity: No biological activity data is available at this time