Resistin-like molecule-gamma (RELM-?) is a member of the RELM family of secreted proteins containing C-terminal cysteines. The RELM family consists of Resistin (FIZZ3), RELM-a (FIZZ1), RELM-ß (FIZZ2), and RELM-? (FIZZ4). RELM-? is secreted by peripheral blood granulocytes, bone marrow, spleen, intestine, and lung. RELM-? functions to promote and regulate promyelocytic differentiation, in addition to regulating nutrient-associated insulin sensitivity in the intestinal tract. Rodents secrete all four RELM family members, whereas Resistin and RELM-ß are the only RELM family members found in humans.
Bioactivity: No biological activity data is available at this time