Interleukin 22 (IL-22), also called IL-TIF, is an IL-10 family member that is produced by activated dendritic cells and T lymphocytes. IL-22 signals via a heteroduplex receptor consisting of IL-22R and IL-10RB chains. IL-22 is a potent mediator of cellular inflammatory responses and wound healing.
Bioactivity Assay:Production of IL-10 from human COLO-205 cells; ED50 =1 ng/mL; Bioactivity =1.0 x 10^6 units/mg