Thrombopoietin (TPO) is a growth factor that is produced by liver and kidney tissues. TPO binds the TPO receptor (CD110) to promote megakaryocyte maturation, differentiation, and the production of platelets. Human TPO (CHO) contains a C-terminal 6x-polyhistidine (6xHis) tag.
Bioactivity Assay:MO7e cell proliferation; ED50 =15 ng/mL; Bioactivity =6.7 x 10^4 units/mg