Macrophage inflammatory protein-3 beta (MIP-3 ß), also called CCL19, is a chemokine that is expressed in the thymus, lymph nodes, and activated bone marrow stromal cells. MIP-3 ß signals through the G protein-coupled receptor CCR7 to regulate normal lymphocyte recirculation. MIP-3 ß also functions during T cell trafficking to the thymus, and in T cell and B cell homing to the lymph nodes and secondary lymphoid organs. Human MIP-3 ß shows activity on mouse cells.
Bioactivity: No biological activity data is available at this time