Interferon-alpha 2b (IFN-a 2b) is a type I interferon made by leukocytes during viral infection. The JAK-STAT pathway mediates the antiviral and anti-cell proliferation activities of IFN-a 2b. IFN-a proteins are widely used as standard treatments during antiviral and antineoplastic therapies. The IFN-a 2b variant differs from IFN-a 2a by one amino acid.
Bioactivity Assay:Viral CPE assay using EMC virus on A549 cells; ED50 =0.005 ng/mL; Bioactivity =2.0 x 10^8 units/mg