Fibroblast growth factor 5 (FGF-5) is a secreted heparin-binding growth factor that binds to FGF receptors 1 and 2 (FGFR1 and FGFR2). FGF-5 is expressed in the mesenchyme, skeletal muscles, central nervous system, and hair follicles to promote cell differentiation and proliferation. FGF-5 functions as a regulatory factor during hair elongation and skeletal muscle development.
Bioactivity Assay:NR6R-3T3 Proliferation with 1 ug heparin; ED50 =10 ng/mL; Bioactivity =1.0 x 10^5 units/mg